Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

NDUFA4

NDUFA4, mitochondrial complex associated is a protein that in humans is encoded by the NDUFA4 gene. The NDUFA4 protein was first described to be a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. However, recent research has described…

Measurement, Structure & Interactions

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around NDUFA4. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NDUFA4, CI-9k, CI-MLRQ, MLRQ, mitochondrial complex associated, COXFA4, NDUFA4 mitochondrial complex associated, MC4DN21, MRCAF1, MISTR1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LEG, 1LEK, 1MWA, 2CKB
Band
7p21.3
Bgee
right ventricle · myocardium · cerebellar vermis · myocardium of left ventricle · pons
BioGPS
n/a
Chr.
Chromosome 7 (human)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

NDUFA4

Nodes19
Edges18
Triples70
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

NDUFA4

Top relations

Gene ontology · 13
NDUFA4 → cytochrome-c oxidase activity, membrane, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex IV, mitochondrion, NADH dehydrogenase (ubiquinone) activity, protein binding, protein-containing complex binding, proton transmembrane transport, respirasome
Bgee · 10
NDUFA4 → biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral nuclear group of thalamus, myocardium, myocardium of left ventricle, pons, prefrontal cortex, right ventricle, Skeletal muscle tissue of biceps brachii
RNA expression pattern · 10
NDUFA4 → biceps brachii, cardiac muscle tissue of right atrium, cerebellar vermis, lateral nuclear group of thalamus, myocardium, myocardium of left ventricle, pons, prefrontal cortex, right ventricle, Skeletal muscle tissue of biceps brachii
related to Clinical significance · 8
NDUFA4 → Complex, Complex IV, COX, Disruption, Given, Leigh, Leigh's, Mutations
related to Interactions · 3
NDUFA4 → CUL3, PARK7, UBL4A
related to Structure · 3
NDUFA4 → Complex, NADH, The NDUFA4
Aliases · 1
NDUFA4 → NDUFA4, CI-9k, CI-MLRQ, MLRQ, mitochondrial complex associated, COXFA4, NDUFA4 mitochondrial complex associated, MC4DN21, MRCAF1, MISTR1
Available structures · 1
NDUFA4 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LEG, 1LEK, 1MWA, 2CKB
Band · 1
NDUFA4 → 7p21.3
BioGPS · 1
NDUFA4 → n/a

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene complex protein mitochondrial subunit chromosome associated human bp iv nadh dehydrogenase ubiquinone cytochrome oxidase chr mutations syndrome described membrane

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
NDUFA4AliasesNDUFA4, CI-9k, CI-MLRQ, MLRQ, mitochondrial complex associated, COXFA4, NDUFA4 mitochondrial complex associated, MC4DN21, MRCAF1, MISTR11.00infobox
NDUFA4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LEG, 1LEK, 1MWA, 2CKB1.00infobox
NDUFA4Band7p21.31.00infobox
NDUFA4Bgeeright ventricle1.00infobox
NDUFA4Bgeemyocardium1.00infobox
NDUFA4Bgeecerebellar vermis1.00infobox
NDUFA4Bgeemyocardium of left ventricle1.00infobox
NDUFA4Bgeepons1.00infobox
NDUFA4Bgeecardiac muscle tissue of right atrium1.00infobox
NDUFA4Bgeeprefrontal cortex1.00infobox
NDUFA4Bgeebiceps brachii1.00infobox
NDUFA4BgeeSkeletal muscle tissue of biceps brachii1.00infobox
NDUFA4Bgeelateral nuclear group of thalamus1.00infobox
NDUFA4BioGPSn/a1.00infobox
NDUFA4Chr.Chromosome 7 (human)1.00infobox
NDUFA4DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFA4End10,940,153 bp1.00infobox
NDUFA4EnsemblENSG000001890431.00infobox
NDUFA4Entrez46971.00infobox
NDUFA4External IDsOMIM: 603833; MGI: 107686; GeneCards: NDUFA41.00infobox
NDUFA4Gene location (Human)Gene location (Human)Chr.Chromosome 7 (human)Band7p21.3Start10,931,943 bpEnd10,940,153 bp1.00infobox
NDUFA4Gene ontologyNADH dehydrogenase (ubiquinone) activity1.00infobox
NDUFA4Gene ontologycytochrome-c oxidase activity1.00infobox
NDUFA4Gene ontologyprotein binding1.00infobox
NDUFA4Gene ontologyprotein-containing complex binding1.00infobox
NDUFA4Gene ontologymitochondrial inner membrane1.00infobox
NDUFA4Gene ontologymitochondrial respiratory chain complex I1.00infobox
NDUFA4Gene ontologyrespirasome1.00infobox
NDUFA4Gene ontologymembrane1.00infobox
NDUFA4Gene ontologymitochondrion1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.