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MYF6: Function, Clinical significance & Overview
Myogenic factor 6 (also known as Mrf4 or herculin) is a protein that in humans is encoded by the MYF6 gene. This gene is also known in the biomedical literature as MRF4 and herculin. MYF6 is a myogenic regulatory factor (MRF) involved in the process known as myogenesis.
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MYF6 topic overview
The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around MYF6.
Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
102
Concept neighborhoods
8
Bridge connections
13
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Function · 4 topics
Overview · 4 topics
Clinical significance · 2 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
How MYF6 connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around MYF6 shows recurring relationship patterns in the source. For example, MYF6 → cell differentiation, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, multicellular organism development, muscle cell fate commitment, muscle organ development, muscle tissue morphogenesis, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, positive regulation of myoblast fusion, positive regulation of skeletal muscle fiber development, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein dimerization activity Another extracted example is MYF6 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, glutes, intercostal muscle, medial head of gastrocnemius muscle, muscle of thigh, quadriceps femoris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
MYF6
Top relations
Gene ontology· 31
MYF6 → cell differentiation, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding, multicellular organism development, muscle cell fate commitment, muscle organ development, muscle tissue morphogenesis, negative regulation of transcription, DNA-templated, nucleoplasm, nucleus, positive regulation of muscle cell differentiation, positive regulation of myoblast differentiation, positive regulation of myoblast fusion, positive regulation of skeletal muscle fiber development, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein dimerization activity
Bgee· 17
MYF6 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, glutes, intercostal muscle, medial head of gastrocnemius muscle, muscle of thigh, quadriceps femoris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle
RNA expression pattern· 17
MYF6 → biceps brachii, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, glutes, intercostal muscle, medial head of gastrocnemius muscle, muscle of thigh, quadriceps femoris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle
related to Function· 12
MYF6 → However, In, Initially, MRF, MRFs, Myf-5, Myf5, MYF6/Mrf4, MyoD, Myogenic, The, This
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 102 structured relationships around MYF6. Examples in this analysis include MYF6 → Aliases → MYF6, CNM3, MRF4, bHLHc4, myf-6, Myf6, myogenic factor 6 and MYF6 → Band → 12q21.31. The table shows each extracted connection, where it came from and its confidence.
Gene location (Human)Chr.Chromosome 12 (human)Band12q21.31Start80,707,634 bpEnd80,709,474 bp
1.00
infobox
No triples extracted yet.
Related concept clusters Concept neighborhoods
Concept neighborhoods group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around MYF6 bring nearby vocabulary together. In this analysis, examples include Gene, Myogenesis and Expressed. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
MYF6
Gene
Myogenesis
Expressed
Mrf
Muscle
Myogenic
Expression
Myf5
Mouse
Protein
Skeletal
Chromosome
myf6
Gene
Myogenesis
Expressed
Mrf
Muscle
Myogenic
Expression
Myf5
Mouse
Protein
Skeletal
Chromosome
gene
Myf6
Chromosome
Location
Mrf4
Human
Mouse
Protein
Bp
Chr
Myogenic
D1
End
myogenic regulatory factor
Myogenic
Function
Process
Known
Location
Transcription
Mrf4
Human
Protein
Gene
Bp
Chr
transcription factors
Myogenic
D1
End
Function
Process
Expression
Family
Location
Regulation
Band
Factor
Human
function
Location
Human
Bp
Chr
Chromosome
Myogenic
D1
End
Process
Transcription
Mrf4
Expression
myogenesis
Regulation
Protein
Process
Family
Expressed
Myogenic
D1
End
Function
Transcription
Expression
Genes
protein
Regulation
Process
Transcription
Genes
Skeletal
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For MYF6, one of the stronger structural bridges in this analysis connects MYF6 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
MYF6
Nodes14
Edges13
Triples102
Avg. degree1.86
Density0.142857
Components1
Source & methodology
TTTA analyzes the structure around MYF6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MYF6 · EN edition · Analysis: TopicsToTalkAbout
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