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MreB

MreB is a protein found in bacteria that is a homolog of actin, a major component of the cytoskeleton in eukaryotes. MreB is one of the most widespread bacterial actin homologs, and together with the tubulin-like protein FtsZ and the intermediate-filament-like protein crescentin it is among the best-studied components of the prokaryotic cytoskeleton. The…

Structure and relationship to actin, Overview & Spatial regulation by cell geometry

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Structure and relationship to actin

Sequence identityFoldATPNucleotide-binding cleftPolymerize
11 related topics

Overview

ProteinBacteriaHomologActinCytoskeleton
19 related topics

Spatial regulation by cell geometry

Gaussian curvatureMembrane curvatureDiameterL-form bacteriaMechanical strain
5 related topics

Distribution across bacteria

ActinobacteriaMycobacteriumCorynebacteriumChlamydiaCell division
5 related topics

Key facts & relationships

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AlphaFold
IPR004753 · PF06723
Available protein structures:
IPR004753 · PF06723
CDD
cd10225
InterPro
IPR004753
PDB
1jce IPR004753 PF06723 (ECOD; PDBsum)
Pfam
PF06723

Topics to explore

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Overview

Discovery and nomenclature

Structure and relationship to actin

Function in cell-wall synthesis and shape

Filament organization and dynamics

Spatial regulation by cell geometry

Distribution across bacteria

Advanced semantic analysis

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Map overview Semantic statistics

MreB

Nodes56
Edges55
Triples60
Avg. degree1.96
Density0.035714
Components1

How this topic connects Entity context

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MreB

Top relations

related to Distribution across bacteria · 15
MreB → Chlamydia, Corynebacterium, DivIVA-family, Genes, LytE, Mbl, MreB's, MreB-based, MreB-family, MreB-like, MreBH, Mycobacterium, PBP2, Some, Wag31
related to Function in cell-wall synthesis and shape · 11
MreB → An, How MreB, In, PBP2, Rather, Rod, Rod-complex, RodA, RodZ, SEDS, These
related to Structure and relationship to actin · 7
MreB → Although MreB, ATP, Caulobacter MreB, GTP, High-resolution, Thermotoga, This
related to Filament organization and dynamics · 6
MreB → Current, Early, Electron, N-terminal, Rod, This
related to Spatial regulation by cell geometry · 6
MreB → Gaussian, In, L-form, MreB-dependent, The, This
related to Discovery and nomenclature · 3
MreB → MreC, MreD, The
AlphaFold · 2
MreB → IPR004753, PF06723
Available protein structures: · 2
MreB → IPR004753, PF06723
CDD · 1
MreB → cd10225
InterPro · 1
MreB → IPR004753

Important terminology Word statistics

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Important terminology

cell filaments protein bacteria actin peptidoglycan coli rod shape cell-wall synthesis cytoskeleton wall helical membrane around width control among subtilis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MreBAlphaFoldIPR0047531.00infobox
MreBAlphaFoldPF067231.00infobox
MreBAvailable protein structures:IPR0047531.00infobox
MreBAvailable protein structures:PF067231.00infobox
MreBCDDcd102251.00infobox
MreBInterProIPR0047531.00infobox
MreBPDB1jce IPR004753 PF06723 (ECOD; PDBsum)1.00infobox
MreBPfamPF067231.00infobox
MreBSymbolMreB1.00infobox
MreBis aprotein found in bacteria that is a homolog of actin0.90text
Corynebacteriuminstance ofnotably Mycobacterium and related genera0.80text
grow mainly from their poles rather than through a canonical MreB-based lateral-wall systeminstance ofnotably Mycobacterium and related genera0.80text

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