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Mecillinam

Mecillinam (INN) or amdinocillin (USAN) is an extended-spectrum penicillin antibiotic of the amidinopenicillin class that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. It is used primarily in the treatment of urinary tract infections, and has also been used to treat typhoid…

History & Applications

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
J01CA11 (WHO)
Bioavailability
Negligible
CAS Number
32887-01-7 Y
ChEMBL
ChEMBL530 Y

Topics to explore

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Overview

Medical uses

Adverse effects

History

Advanced semantic analysis

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Map overview Semantic statistics

Mecillinam

Nodes30
Edges29
Triples46
Avg. degree1.93
Density0.066667
Components1

How this topic connects Entity context

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Mecillinam

Top relations

related to Medical uses · 13
Mecillinam → Another, Brazil, Canada, Escherichia, Europe, European, Gram-negative, Gram-positive, Proteus, Pseudomonas, Several, Staphylococcus, Worldwide
related to history · 6
Mecillinam → Danish, FL, It, LEO Pharma, Leo Pharmaceutical Products, With
Legal status · 3
Mecillinam → AU: S4 (Prescription only), In general: ℞ (Prescription only), UK: POM (Prescription only)
has effect · 2
Mecillinam → Its, The
3D model (JSmol) · 1
Mecillinam → Interactive image
AHFS/Drugs.com · 1
Mecillinam → International Drug Names
ATC code · 1
Mecillinam → J01CA11 (WHO)
Bioavailability · 1
Mecillinam → Negligible
CAS Number · 1
Mecillinam → 32887-01-7 Y
ChEMBL · 1
Mecillinam → ChEMBL530 Y

Important terminology Word statistics

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Important terminology

bacteria active gram-negative urinary tract bioavailability binding protein coli used treatment infections also low developed adverse effects proteus leo inn

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mecillinam3D model (JSmol)Interactive image1.00infobox
MecillinamAHFS/Drugs.comInternational Drug Names1.00infobox
MecillinamATC codeJ01CA11 (WHO)1.00infobox
MecillinamBioavailabilityNegligible1.00infobox
MecillinamCAS Number32887-01-7 Y1.00infobox
MecillinamChEMBLChEMBL530 Y1.00infobox
MecillinamChemSpider33357 N1.00infobox
MecillinamCompTox Dashboard (EPA)DTXSID30225841.00infobox
MecillinamDrugBankDB01163 Y1.00infobox
MecillinamECHA InfoCard100.046.6011.00infobox
MecillinamElimination half-life1 to 3 hours1.00infobox
MecillinamExcretionRenal and biliary, mostly unchanged1.00infobox
MecillinamFormulaC15H23N3O3S1.00infobox
MecillinamKEGGD02888 N1.00infobox
MecillinamLegal statusAU: S4 (Prescription only)1.00infobox
MecillinamLegal statusUK: POM (Prescription only)1.00infobox
MecillinamLegal statusIn general: ℞ (Prescription only)1.00infobox
MecillinamMetabolismSome hepatic metabolism1.00infobox
MecillinamMolar mass325.43 g·mol−11.00infobox
MecillinamPregnancy categoryAppears safe in pregnancy1.00infobox
MecillinamProtein binding5 to 10%1.00infobox
MecillinamPubChem CID362731.00infobox
MecillinamRoutes of administrationIntravenous, intramuscular1.00infobox
MecillinamTrade namesCoactin, Leo, Selexid, Selexidin1.00infobox
MecillinamUNIIV10579P3QZ1.00infobox

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