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Malonyl-CoA decarboxylase

Malonyl-CoA decarboxylase (EC 4.1.1.9), (which can also be called MCD and malonyl-CoA carboxyl-lyase) is found in bacteria and humans and has important roles in regulating fatty acid metabolism and food intake, and it is an attractive target for drug discovery. It is an enzyme associated with Malonyl-CoA decarboxylase deficiency. In humans, it is encoded…

Applications, Processing and post-translational modifications & Functions

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Processing and post-translational modifications

Pro-proteinProenzymeTransit peptideMethionineAlanine
13 related topics

Functions

EnzymePeroxisomesFatty acidsPropionyl-CoASuccinyl-CoA
13 related topics

Structure

IsoformsTetramerOligomerN-terminusC-terminus
9 related topics

Medical applications

IschaemiaReperfusion injury
2 related topics

Key facts & relationships

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BRENDA
enzyme data
CAS no.
9024-99-1
EC no.
4.1.1.9
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

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Overview

Structure

Processing and post-translational modifications

Functions

Localization

Enzyme regulation

Medical applications

Advanced semantic analysis

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Map overview Semantic statistics

Malonyl-CoA decarboxylase

Nodes60
Edges59
Triples46
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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Malonyl-CoA decarboxylase

Top relations

related to Functions · 10
Malonyl-CoA decarboxylase → After, As, CoA, In, Malonyl-CoA, MCD, Most, The, This, To
related to Processing and post-translational modifications · 9
Malonyl-CoA decarboxylase → Another, CoA, In, Malonyl-CoA, MCD, PTM, Similarly, SIRT4, The
related to Gene: MLYCD · 6
Malonyl-CoA decarboxylase → CoA, It, MCD, MLYCD, The, This
related to Localization · 3
Malonyl-CoA decarboxylase → In, Malonyl-CoA, MCD
BRENDA · 1
Malonyl-CoA decarboxylase → enzyme data
CAS no. · 1
Malonyl-CoA decarboxylase → 9024-99-1
EC no. · 1
Malonyl-CoA decarboxylase → 4.1.1.9
ExPASy · 1
Malonyl-CoA decarboxylase → NiceZyme view
Gene Ontology · 1
Malonyl-CoA decarboxylase → AmiGO / QuickGO
KEGG · 1
Malonyl-CoA decarboxylase → enzyme entry

Important terminology Word statistics

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Important terminology

malonyl-coa mcd fatty enzyme acid decarboxylase acetyl-coa also peroxisomes gene acids mitochondrial mlycd mitochondria one amino oxidation malonic peroxisomal sites

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Malonyl-CoA decarboxylaseBRENDAenzyme data1.00infobox
Malonyl-CoA decarboxylaseCAS no.9024-99-11.00infobox
Malonyl-CoA decarboxylaseEC no.4.1.1.91.00infobox
Malonyl-CoA decarboxylaseExPASyNiceZyme view1.00infobox
Malonyl-CoA decarboxylaseGene OntologyAmiGO / QuickGO1.00infobox
Malonyl-CoA decarboxylaseKEGGenzyme entry1.00infobox
Malonyl-CoA decarboxylaseMetaCycmetabolic pathway1.00infobox
Malonyl-CoA decarboxylaseNCBIproteins1.00infobox
Malonyl-CoA decarboxylasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Malonyl-CoA decarboxylasePMCarticles1.00infobox
Malonyl-CoA decarboxylasePubMedarticles1.00infobox
Malonyl-CoA decarboxylaseRheareactions1.00infobox
Malonyl-CoA decarboxylaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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