Mitochondrial disease

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Explore the main themes, entities and connections around Mitochondrial disease. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Causes

Mutations Mitochondrial DNA Nuclear genes Drugs Infections

24 related topics

Treatments

Vitamins Pyruvate N-acetyl cysteine Acetyl-L-carnitine S-adenosylmethionine

19 related topics

Types

Diabetes mellitus and deafness Diabetes mellitus Deafness Kearns–Sayre syndrome Pearson syndrome

17 related topics

Presentation

ALS Alzheimer's disease Bipolar disorder Schizophrenia Cancer

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Key facts & relationships

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Other names: Mitochondrial cytopathy; mitochondriopathy (MCP)
Specialty: Medical genetics

Topics to explore

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Overview

Genetic disorders Genetic disorder
Mitochondria
Organelles Organelle
Cell Cell (biology)
Red blood cells Red blood cell
ATP Adenosine triphosphate
Neuromuscular symptoms Neuromuscular disease
Mitochondrial myopathies Mitochondrial myopathy

Types

Diabetes mellitus and deafness
Diabetes mellitus
Deafness
Kearns–Sayre syndrome
Pearson syndrome
Leber's hereditary optic neuropathy
Leigh syndrome
Neuropathy, ataxia, retinitis pigmentosa, and ptosis Neuropathy, ataxia, and retinitis pigmentosa
Dementia
Myoneurogenic gastrointestinal encephalopathy
Neuropathy
MERRF syndrome
Subsarcolemmal Sarcolemma
Gömöri trichrome stain
MELAS syndrome
Mitochondrial DNA depletion syndrome
Friedreich's ataxia

Presentation

Mechanisms

Diagnosis

Treatments

Vitamins Vitamin
Pyruvate
N-acetyl cysteine
Acetyl-L-carnitine
S-adenosylmethionine S-Adenosyl methionine
Coenzyme Q10
Alpha-lipoic acid
Creatine monohydrate
Melatonin Melatonin as a medication and supplement
Mitochondrial replacement therapy
IVF
Pronuclear transfer Pronuclear transfer?action=edit&redlink=1
Newcastle University
Douglass Turnbull
Ethical issues Three-parent baby
United Kingdom
Embryonic Embryo
Protofection
Allotopic expression

Epidemiology

United States

Notable cases

Advanced semantic analysis

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Map overview Semantic statistics

Nodes109

Edges108

Triples70

Avg. degree1.98

Density0.018349

Components1

How this topic connects Entity context

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Mitochondrial disease

Top relations

related to Gene therapy prior to conception · 18

Mitochondrial disease → DNA, Douglass Turnbull, Embryonic, Human, In, In June, In September, IVF, Leigh, Mexico, Mitochondrial, MRT, Newcastle University, October, The, UK, United Kingdom, Using

related to Types · 17

Mitochondrial disease → DNA, ECAR, Examples, Gömöri, Kearns, Key, LHON, MIDD, Mitochondrial, MNGIE, NARP, Pearson, Ragged Red Fibers, Sayre, Tumor, Warburg, While

has cause · 9

Mitochondrial disease → As, DNA, During, If, Mitochondrial, Mitochondrial DNA, Nuclear DNA, They, Those

related to Notable cases · 9

Mitochondrial disease → British, Charles Darwin, Charlie Gard, DNA, Major League Baseball, Mattie Stepanek, MELAS, Notable, Rocco Baldelli

related to Epidemiology · 7

Mitochondrial disease → About, Because, The, United Kingdom, United States, Up, US

related to Diagnosis · 3

Mitochondrial disease → Mitochondrial, Southern, The

Other names · 1

Mitochondrial disease → Mitochondrial cytopathy; mitochondriopathy (MCP)

Specialty · 1

Mitochondrial disease → Medical genetics

is a · 1

Mitochondrial disease → group of genetic disorders caused by mitochondrial dysfunction

Important terminology Word statistics

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Important terminology

mitochondrial mitochondria disease cells dna diseases cell energy may disorders human inherited mutations mtdna body research nuclear treatment cancer many

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Mitochondrial disease	Other names	Mitochondrial cytopathy; mitochondriopathy (MCP)	1.00	infobox
Mitochondrial disease	Specialty	Medical genetics	1.00	infobox
Mitochondrial disease	is a	group of genetic disorders caused by mitochondrial dysfunction	0.90	text
oxygen flux	instance of	Key bioenergetic parameters	0.80	text
proton leakage	instance of	Key bioenergetic parameters	0.80	text
membrane potential	instance of	Key bioenergetic parameters	0.80	text
extracellular acidification rate	instance of	Key bioenergetic parameters	0.80	text
Mitochondrial disease	has cause	Mitochondrial	0.60	section
Mitochondrial disease	has cause	DNA	0.60	section
Mitochondrial disease	has cause	They	0.60	section
Mitochondrial disease	has cause	Nuclear DNA	0.60	section
Mitochondrial disease	has cause	Mitochondrial DNA	0.60	section

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