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Mitochondrial threshold effect is a phenomenon where the number of mutated mtDNA has surpassed a certain threshold which causes the electron transport chain and ATP synthesis of a mitochondrion to fail. There isn't a set number that needs to be surpassed, however, it is associated with an increase of the number of mutated mtDNA. When there is 60-80% of…
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mtdna threshold number mutated level effect mutant mutation atp phenotypic however present mitochondrial phenomenon surpassed 60-80 specific organ citation needed
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Threshold expression | is a | phenomenon in which phenotypic expression of a mitochondrial disease within an organ system occurs when the severity of the mutation | 0.90 | text |
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