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Midkine

Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene.

Overview, Role in cancer & Trivia

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Overview

18 related topics

Role in cancer

6 related topics

Trivia

3 related topics

HIV infection

1 related topics

Key facts & relationships

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Aliases
MDK, ARAP, MK, NEGF2, midkine (neurite growth-promoting factor 2), midkine
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MKC, 1MKN
Band
11p11.2 · 2 E1|2 50.63 cM
Bgee
ventricular zone · stromal cell of endometrium · pituitary gland · left ovary · canal of the cervix
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Role in cancer

HIV infection

Trivia

Advanced semantic analysis

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Map overview Semantic statistics

Midkine

Nodes33
Edges32
Triples102
Avg. degree1.94
Density0.060606
Components1

How this topic connects Entity context

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Midkine

Top relations

Gene ontology · 29
Midkine → adrenal gland development, behavioral fear response, cell differentiation, cell migration, cell projection, cerebellar granular layer development, cerebral cortex development, collagen-containing extracellular matrix, cytoplasm, defecation, dentate gyrus development, extracellular region, growth factor activity, heparin binding, hippocampus development, multicellular organism development, negative regulation of neuron apoptotic process, negative regulation of neuron death, nervous system development, Notch signaling pathway
Bgee · 17
Midkine → anterior pituitary, canal of the cervix, duodenum, embryo, epiblast, ganglionic eminence, genital tubercle, left ovary, neural tube, pituitary gland, right ovary, right uterine tube, stromal cell of endometrium, tail of embryo, uterus, ventricular zone, yolk sac
RNA expression pattern · 17
Midkine → anterior pituitary, canal of the cervix, duodenum, embryo, epiblast, ganglionic eminence, genital tubercle, left ovary, neural tube, pituitary gland, right ovary, right uterine tube, stromal cell of endometrium, tail of embryo, uterus, ventricular zone, yolk sac
related to External links · 5
Midkine → Overview, P21741, PDB, PDBe-KB, UniProt
related to Trivia · 4
Midkine → Change, In, Japanese, World
Band · 2
Midkine → 11p11.2, 2 E1|2 50.63 cM
Chr. · 2
Midkine → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
Midkine → 46,383,837 bp, 91,762,642 bp
related to HIV infection · 2
Midkine → HIV, This
Aliases · 1
Midkine → MDK, ARAP, MK, NEGF2, midkine (neurite growth-promoting factor 2), midkine

Important terminology Word statistics

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Important terminology

mk cells protein cell gene cancer bp factor neuroblastoma mdk chr human band resistant wt chromosome 11 molecular chemotherapeutic also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MidkineAliasesMDK, ARAP, MK, NEGF2, midkine (neurite growth-promoting factor 2), midkine1.00infobox
MidkineAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1MKC, 1MKN1.00infobox
MidkineBand11p11.21.00infobox
MidkineBand2 E1|2 50.63 cM1.00infobox
MidkineBgeeventricular zone1.00infobox
MidkineBgeestromal cell of endometrium1.00infobox
MidkineBgeepituitary gland1.00infobox
MidkineBgeeleft ovary1.00infobox
MidkineBgeecanal of the cervix1.00infobox
MidkineBgeeanterior pituitary1.00infobox
MidkineBgeeright uterine tube1.00infobox
MidkineBgeeganglionic eminence1.00infobox
MidkineBgeeduodenum1.00infobox
MidkineBgeeright ovary1.00infobox
MidkineBgeegenital tubercle1.00infobox
MidkineBgeetail of embryo1.00infobox
MidkineBgeeyolk sac1.00infobox
MidkineBgeeepiblast1.00infobox
MidkineBgeeuterus1.00infobox
MidkineBgeeneural tube1.00infobox
MidkineBgeeembryo1.00infobox
MidkineBioGPSMore reference expression data1.00infobox
MidkineChr.Chromosome 11 (human)1.00infobox
MidkineChr.Chromosome 2 (mouse)1.00infobox
MidkineDatabasesNCBI: entry; OMA: entry1.00infobox
MidkineEnd46,383,837 bp1.00infobox
MidkineEnd91,762,642 bp1.00infobox
MidkineEnsemblENSG000001104921.00infobox
MidkineEntrez41921.00infobox
MidkineExternal IDsOMIM: 162096; MGI: 96949; GeneCards: MDK1.00infobox

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