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Michael Oldstone

Michael Beaureguard Alan Oldstone (February 9, 1932 – July 13, 2023) was an American virologist and immunologist known for his work on viral pathogenesis, a field of which he is considered one of the founders. He and his group originated several important concepts, including molecular mimicry, disease associated with immune complexes, and the idea that…

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Michael Oldstone

Nodes92
Edges91
Triples9
Avg. degree1.98
Density0.021739
Components1

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oldstone virus viruses viral immune research pathogenesis disease persistent infection lcmv mice science measles also mouse history influenza university associated

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SubjectPredicateObjectConfidenceSrc
oseltamivir in this modelinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
and also suggests that drugs targeting the sphingosine-1-phosphate pathway could be effective against hantavirusinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
severe acute respiratory syndrome coronavirus 1instance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
where cytokine storms are known to contribute to the pathology.MeaslesMeasles virusinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
another negative-stranded RNA virusinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
was another research focusinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text
measles to evade the immune responseinstance ofcould enable viruses0.80text
thus tipping the balance towards viral persistenceinstance ofcould enable viruses0.80text
where cytokine storms are known to contribute to the pathologyinstance ofTheir research gave proof of concept that immune modulators could reduce influenza mortality at least as well as neuraminidase inhibitors0.80text

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