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Dual specificity mitogen-activated protein kinase kinase 5 is an enzyme that in humans is encoded by the MAP2K5 gene.
The analysis highlights Interactions and Overview as prominent areas in the source structure around MAP2K5.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around MAP2K5 shows recurring relationship patterns in the source. For example, MAP2K5 → activation of protein kinase activity, ATP binding, cellular response to growth factor stimulus, cellular response to laminar fluid shear stress, cytoplasm, cytosol, development of the heart, ERK5 cascade, intracellular anatomical structure, kinase activity, MAP kinase kinase activity, MAPK cascade, metal ion binding, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of heterotypic cell-cell adhesion, negative regulation of NF-kappaB transcription factor activity, negative regulation of response to cytokine stimulus Another extracted example is MAP2K5 → Achilles tendon, Brodmann area 9, CA3 field, external carotid artery, gastrocnemius muscle, gonad, internal carotid artery, left lobe of liver, left testis, motor neuron, parotid gland, prefrontal cortex, primitive streak, right frontal lobe, right kidney, right testis, Rostral migratory stream, seminiferous tubule, spermatocyte, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
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kinase protein bp gene chr human band chromosome 15 location mapk7 map3k3 enzyme mouse erk5 mitogen-activated function isoforms dual specificity
TTTA extracted 109 structured relationships around MAP2K5. Examples in this analysis include MAP2K5 → 2.7.12.2 → ↗ and MAP2K5 → Aliases → MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAP2K5 | 2.7.12.2 | ↗ | 1.00 | infobox |
| MAP2K5 | Aliases | MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5 | 1.00 | infobox |
| MAP2K5 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2NPT, 2O2V, 4IC7 | 1.00 | infobox |
| MAP2K5 | Band | 15q23 | 1.00 | infobox |
| MAP2K5 | Band | 9|9 B- C | 1.00 | infobox |
| MAP2K5 | Bgee | right testis | 1.00 | infobox |
| MAP2K5 | Bgee | left testis | 1.00 | infobox |
| MAP2K5 | Bgee | parotid gland | 1.00 | infobox |
| MAP2K5 | Bgee | gonad | 1.00 | infobox |
| MAP2K5 | Bgee | right frontal lobe | 1.00 | infobox |
| MAP2K5 | Bgee | Achilles tendon | 1.00 | infobox |
| MAP2K5 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| MAP2K5 | Bgee | ventricular zone | 1.00 | infobox |
| MAP2K5 | Bgee | Brodmann area 9 | 1.00 | infobox |
| MAP2K5 | Bgee | prefrontal cortex | 1.00 | infobox |
| MAP2K5 | Bgee | internal carotid artery | 1.00 | infobox |
| MAP2K5 | Bgee | external carotid artery | 1.00 | infobox |
| MAP2K5 | Bgee | motor neuron | 1.00 | infobox |
| MAP2K5 | Bgee | Rostral migratory stream | 1.00 | infobox |
| MAP2K5 | Bgee | spermatocyte | 1.00 | infobox |
| MAP2K5 | Bgee | CA3 field | 1.00 | infobox |
| MAP2K5 | Bgee | right kidney | 1.00 | infobox |
| MAP2K5 | Bgee | seminiferous tubule | 1.00 | infobox |
| MAP2K5 | Bgee | primitive streak | 1.00 | infobox |
| MAP2K5 | Bgee | left lobe of liver | 1.00 | infobox |
| MAP2K5 | BioGPS | More reference expression data | 1.00 | infobox |
| MAP2K5 | Chr. | Chromosome 15 (human) | 1.00 | infobox |
| MAP2K5 | Chr. | Chromosome 9 (mouse) | 1.00 | infobox |
| MAP2K5 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAP2K5 | End | 67,807,117 bp | 1.00 | infobox |
The concept neighborhoods around MAP2K5 bring nearby vocabulary together. In this analysis, examples include Protein, Activity and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAP2K5, one of the stronger structural bridges in this analysis connects MAP2K5 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAP2K5 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAP2K5 · EN edition · Analysis: TopicsToTalkAbout
