MAP2K5

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Explore the main themes, entities and connections around MAP2K5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact MAPK7 MAP3K2 Protein kinase Mζ MAP3K3

5 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

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2.7.12.2: ↗
Aliases: MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2NPT, 2O2V, 4IC7
Band: 15q23 · 9|9 B- C
Bgee: right testis · left testis · parotid gland · gonad · right frontal lobe
BioGPS: More reference expression data

Topics to explore

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Overview

Interactions

Interact Protein-protein interaction
MAPK7
MAP3K2
Protein kinase Mζ
MAP3K3

Advanced semantic analysis

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Map overview Semantic statistics

Nodes10

Edges9

Triples109

Avg. degree1.8

Density0.2

Components1

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MAP2K5

Top relations

Gene ontology · 39

MAP2K5 → activation of protein kinase activity, ATP binding, cellular response to growth factor stimulus, cellular response to laminar fluid shear stress, cytoplasm, cytosol, development of the heart, ERK5 cascade, intracellular anatomical structure, kinase activity, MAP kinase kinase activity, MAPK cascade, metal ion binding, negative regulation of cell migration involved in sprouting angiogenesis, negative regulation of chemokine (C-X-C motif) ligand 2 production, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of extrinsic apoptotic signaling pathway in absence of ligand, negative regulation of heterotypic cell-cell adhesion, negative regulation of NF-kappaB transcription factor activity, negative regulation of response to cytokine stimulus

Bgee · 20

MAP2K5 → Achilles tendon, Brodmann area 9, CA3 field, external carotid artery, gastrocnemius muscle, gonad, internal carotid artery, left lobe of liver, left testis, motor neuron, parotid gland, prefrontal cortex, primitive streak, right frontal lobe, right kidney, right testis, Rostral migratory stream, seminiferous tubule, spermatocyte, ventricular zone

RNA expression pattern · 20

related to Interactions · 5

MAP2K5 → MAP3K2, MAP3K3, MAPK7, Mζ, Protein

Band · 2

MAP2K5 → 15q23, 9|9 B- C

Chr. · 2

MAP2K5 → Chromosome 15 (human), Chromosome 9 (mouse)

End · 2

MAP2K5 → 63,285,184 bp, 67,807,117 bp

2.7.12.2 · 1

MAP2K5 → ↗

Aliases · 1

MAP2K5 → MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5

Available structures · 1

MAP2K5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2NPT, 2O2V, 4IC7

Important terminology Word statistics

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Important terminology

kinase protein bp gene chr human band chromosome 15 location mapk7 map3k3 enzyme mouse erk5 mitogen-activated function isoforms dual specificity

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
MAP2K5	2.7.12.2	↗	1.00	infobox
MAP2K5	Aliases	MAP2K5, HsT17454, MAPKK5, MEK5, PRKMK5, mitogen-activated protein kinase kinase 5	1.00	infobox
MAP2K5	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2NPT, 2O2V, 4IC7	1.00	infobox
MAP2K5	Band	15q23	1.00	infobox
MAP2K5	Band	9\|9 B- C	1.00	infobox
MAP2K5	Bgee	right testis	1.00	infobox
MAP2K5	Bgee	left testis	1.00	infobox
MAP2K5	Bgee	parotid gland	1.00	infobox
MAP2K5	Bgee	gonad	1.00	infobox
MAP2K5	Bgee	right frontal lobe	1.00	infobox
MAP2K5	Bgee	Achilles tendon	1.00	infobox
MAP2K5	Bgee	gastrocnemius muscle	1.00	infobox
MAP2K5	Bgee	ventricular zone	1.00	infobox
MAP2K5	Bgee	Brodmann area 9	1.00	infobox
MAP2K5	Bgee	prefrontal cortex	1.00	infobox
MAP2K5	Bgee	internal carotid artery	1.00	infobox
MAP2K5	Bgee	external carotid artery	1.00	infobox
MAP2K5	Bgee	motor neuron	1.00	infobox
MAP2K5	Bgee	Rostral migratory stream	1.00	infobox
MAP2K5	Bgee	spermatocyte	1.00	infobox
MAP2K5	Bgee	CA3 field	1.00	infobox
MAP2K5	Bgee	right kidney	1.00	infobox
MAP2K5	Bgee	seminiferous tubule	1.00	infobox
MAP2K5	Bgee	primitive streak	1.00	infobox
MAP2K5	Bgee	left lobe of liver	1.00	infobox
MAP2K5	BioGPS	More reference expression data	1.00	infobox
MAP2K5	Chr.	Chromosome 15 (human)	1.00	infobox
MAP2K5	Chr.	Chromosome 9 (mouse)	1.00	infobox
MAP2K5	Databases	NCBI: entry; OMA: entry	1.00	infobox
MAP2K5	End	67,807,117 bp	1.00	infobox

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