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Magnetofection

Magnetofection is a transfection method that uses magnetic fields to concentrate particles containing vectors to target cells in the body. Magnetofection has been adapted to a variety of vectors, including nucleic acids, non-viral transfection systems, and viruses. This method offers advantages such as high transfection efficiency and biocompatibility…

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Mechanism

TrademarkedMagnetic nanoparticlesCellsMagnetic fieldIron oxide
27 related topics

Applications

Cell linesNeural stem cells
2 related topics

Advantages

LipidsVacuolesCapillariesThrombosis
4 related topics

Disadvantages

Iron overload
1 related topics

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Overview

Mechanism

Applications

Advantages

Disadvantages

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Map overview Semantic statistics

Magnetofection

Nodes45
Edges44
Triples20
Avg. degree1.96
Density0.044444
Components1

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Magnetofection

Top relations

has application · 3
Magnetofection → DNA, Several, This
related to Localization in vivo · 3
Magnetofection → In, The, While
related to Principle · 3
Magnetofection → OZ Biosciences, The, These
is a · 1
Magnetofection → transfection method that uses magnetic fields to concentrate particles containing vectors to target cells in the body
related to Advantages · 1
Magnetofection → It

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Important terminology

cells magnetic transfection nanoparticles particles vectors gene efficiency dna cell high method field iron delivery body nucleic acids biocompatibility synthesis

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Magnetofectionis atransfection method that uses magnetic fields to concentrate particles containing vectors to target cells in the body0.90text
high transfection efficiencyinstance ofThis method offers advantages0.80text
biocompatibility which are balanced with limitationsinstance ofThis method offers advantages0.80text
coprecipitation or microemulsion.The nanoparticles are then combined with gene vectorsinstance ofusing methods0.80text
electroporation or gene guns that damage the cell membrane.The nucleic acids are then released into the cytoplasm by different mechanisms depending upon the formulation usedinstance ofin contrast to other physical transfection methods0.80text
DNAinstance ofSeveral optimized and efficient magnetic nanoparticle formulations have been specifically developed for several types of applications0.80text
siRNAinstance ofSeveral optimized and efficient magnetic nanoparticle formulations have been specifically developed for several types of applications0.80text
and primary neuron transfection as well as viral applications.Magnetofection research is currently in the preclinical stageinstance ofSeveral optimized and efficient magnetic nanoparticle formulations have been specifically developed for several types of applications0.80text
on a culture plate or at the surface of the bodyinstance ofThe nanoparticles can be concentrated in 2D space0.80text
but it can be more difficult to localize them in the 3D space of the bodyinstance ofThe nanoparticles can be concentrated in 2D space0.80text
Magnetofectionhas applicationSeveral0.60section
Magnetofectionhas applicationDNA0.60section

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