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Macrocycle

Macrocycles are often described as molecules and ions containing a ring of twelve or more atoms. Classical examples include the crown ethers, calixarenes, porphyrins, and cyclodextrins. Macrocycles describe a large, mature area of chemistry.

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Overview

Synthesis

Stereocontrol

Occurrence and applications

Macrocycles in Drug Discovery

Subdivisions

Advanced semantic analysis

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Map overview Semantic statistics

Macrocycle

Nodes63
Edges62
Triples58
Avg. degree1.97
Density0.031746
Components1

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Macrocycle

Top relations

related to Further reading · 27
Macrocycle → A-K, Angewandte Chemie International Edition, Applications, Chambron, Chem, Concepts, Conjugated Macrocycles, Dietrich-Buchecker, Hemmert, Interlacing, ISSN, Iyoda, J-C, J-P, Jalilur, Jun, Khemiss, Masahiko, Mitchell, PDF
related to Synthesis · 12
Macrocycle → An, Dieckmann, Early, High, Instead, Reactions, Ružička, So, Some, Templates, The, This
has application · 5
Macrocycle → Macrocycles, Many, One, The, These
related to Reactivity and conformational preferences · 5
Macrocycle → Conformation, Curtin-Hammett, In, The, TS
related to Stereocontrol · 5
Macrocycle → Early, Investigations, Macrocyclic, NMR, Stereocontrol
related to Conformational preferences · 3
Macrocycle → Conformational, Macrocycles, Medium

Important terminology Word statistics

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Important terminology

macrocyclic conformation ring rings state stereocontrol macrocycles conformational energy ground conformations reactions reaction peripheral attack interactions methyl molecules synthesis preferences

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
in the synthesis of miyakolide.Reaction classes used in synthesis of natural products under the macrocyclic stereocontrol model for obtaining a desired stereochemistry includeinstance ofproviding stereocontrol0.80text
Macrocyclehas applicationOne0.60section
Macrocyclehas applicationMany0.60section
Macrocyclehas applicationThese0.60section
Macrocyclehas applicationMacrocycles0.60section
Macrocyclehas applicationThe0.60section
Macrocyclerelated to Conformational preferencesMacrocycles0.60section
Macrocyclerelated to Conformational preferencesMedium0.60section
Macrocyclerelated to Conformational preferencesConformational0.60section
Macrocyclerelated to Further readingChambron0.60section
Macrocyclerelated to Further readingJ-C0.60section
Macrocyclerelated to Further readingDietrich-Buchecker0.60section

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