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Irbesartan: History, Community, Culture & Applications

Irbesartan, sold under the brand name Aprovel among others, is a medication used to treat hypertension (high blood pressure), heart failure, and diabetic kidney disease. It is a reasonable initial treatment for high blood pressure. It is taken by mouth. Versions are available as the combination irbesartan/hydrochlorothiazide.

Language: English [EN]
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Irbesartan topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Irbesartan.

Related topics
24
Source areas
6
Connected nodes
30
Extracted relationships
52
Concept neighborhoods
20
Bridge connections
30

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Side effects · 6 topics
Overview · 5 topics
Society and culture · 5 topics
History · 4 topics
Mechanism of action · 2 topics
Medical uses · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C09CA04 (WHO) C09DA04 (WHO)
Bioavailability
60% to 80%
CAS Number
138402-11-6 Y
ChEBI
CHEBI:5959 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Side effects

Mechanism of action

History

Society and culture

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Irbesartan connects Entity context

The extracted context around Irbesartan shows recurring relationship patterns in the source. For example, Irbesartan → Aprovel, Avapro, Bristol-Myers Squibb, In, It, Karvea, Sanofi Research, Sanofi-Aventis, United States Another extracted example is Irbesartan → Drug Administration, FDA, Health Canada, II, In, September, The FDA, US Food. Use these groups to spot repeated connection types before inspecting the individual relationships.

Irbesartan

Top relations

related to history · 9
Irbesartan → Aprovel, Avapro, Bristol-Myers Squibb, In, It, Karvea, Sanofi Research, Sanofi-Aventis, United States
related to Recalls · 8
Irbesartan → Drug Administration, FDA, Health Canada, II, In, September, The FDA, US Food
Legal status · 5
Irbesartan → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
3D model (JSmol) · 1
Irbesartan → Interactive image
AHFS/Drugs.com · 1
Irbesartan → Monograph
ATC code · 1
Irbesartan → C09CA04 (WHO) C09DA04 (WHO)
Bioavailability · 1
Irbesartan → 60% to 80%
CAS Number · 1
Irbesartan → 138402-11-6 Y
ChEBI · 1
Irbesartan → CHEBI:5959 Y
ChEMBL · 1
Irbesartan → ChEMBL1513 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

blood pressure kidney effects combination aprovel hypertension medication available high nitrosamine side hydrochlorothiazide name others mouth may also impurities brand

Irbesartan relationships Subject–Predicate–Object triples

TTTA extracted 52 structured relationships around Irbesartan. Examples in this analysis include Irbesartan → 3D model (JSmol) → Interactive image and Irbesartan → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Irbesartan3D model (JSmol)Interactive image1.00infobox
IrbesartanAHFS/Drugs.comMonograph1.00infobox
IrbesartanATC codeC09CA04 (WHO) C09DA04 (WHO)1.00infobox
IrbesartanBioavailability60% to 80%1.00infobox
IrbesartanCAS Number138402-11-6 Y1.00infobox
IrbesartanChEBICHEBI:5959 Y1.00infobox
IrbesartanChEMBLChEMBL1513 Y1.00infobox
IrbesartanChemSpider3618 Y1.00infobox
IrbesartanCompTox Dashboard (EPA)DTXSID00231691.00infobox
IrbesartanDrug classCardiovascular agent1.00infobox
IrbesartanDrugBankDB01029 Y1.00infobox
IrbesartanECHA InfoCard100.119.9661.00infobox
IrbesartanElimination half-life11 h to 15 h1.00infobox
IrbesartanExcretionKidney 20%, feces 65%1.00infobox
IrbesartanFormulaC25H28N6O1.00infobox
IrbesartanIUPHAR/BPS5891.00infobox
IrbesartanKEGGD00523 Y1.00infobox
IrbesartanLegal statusAU: S4 (Prescription only)1.00infobox
IrbesartanLegal statusUK: POM (Prescription only)1.00infobox
IrbesartanLegal statusUS: ℞-only1.00infobox
IrbesartanLegal statusEU: Rx-only1.00infobox
IrbesartanLegal statusIn general: ℞ (Prescription only)1.00infobox
IrbesartanLicense dataUS DailyMed: Irbesartan1.00infobox
IrbesartanMedlinePlusa6980091.00infobox
IrbesartanMetabolismLiver (CYP2C9)1.00infobox
IrbesartanMolar mass428.540 g·mol−11.00infobox
IrbesartanPregnancy categoryAU: D1.00infobox
IrbesartanPronunciation/ɜːrbəˈsɑːrtən/1.00infobox
IrbesartanProtein binding~90%1.00infobox
IrbesartanPubChem CID37491.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Irbesartan bring nearby vocabulary together. In this analysis, examples include Combination, Administration and Angiotensin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Irbesartan
    • Combination
    • Administration
    • Angiotensin
    • Diuretic
    • Drug
    • Drugs
    • Hydrochlorothiazide
    • Name
    • Others
    • Us
    • Used
    • Versions
  • irbesartan
    • Combination
    • Administration
    • Angiotensin
    • Diuretic
    • Drug
    • Drugs
    • Hydrochlorothiazide
    • Name
    • Others
    • Us
    • Used
    • Versions
  • hypertension
    • Diabetic
    • Disease
    • Name
    • Others
    • Used
    • Kidney
    • Administration
    • Diuretic
    • Drug
    • Drugs
    • High
    • Irbesartan
  • diabetic kidney disease
    • Disease
    • Hypertension
    • Name
    • Others
    • Used
    • Pressure
    • Side
    • Effects
    • High
    • Administration
    • Also
    • Diuretic
  • food and drug administration
    • Drug
    • Drugs
    • Us
    • Angiotensin
    • Diuretic
    • Medical
    • Mouth
    • Name
    • Names
    • Others
    • Pregnancy
    • Treatment
  • fixed-dose combination
    • Diuretic
    • Hydrochlorothiazide
    • Irbesartan
    • Administration
    • Drug
    • Drugs
    • Medical
    • Mouth
    • Name
    • Names
    • Others
    • Pregnancy
  • kidney problems
    • Name
    • Others
    • Used
    • Pressure
    • Side
    • Effects
    • Administration
    • Diuretic
    • Drug
    • Drugs
    • Include
    • Medical
  • brand names
    • Aprovel
    • Diabetic
    • Disease
    • High
    • Mouth
    • Name
    • Names
    • Others
    • Pregnancy
    • Sanofi-aventis
    • Treatment
    • Us

Connections between topic areas Semantic bridges

For Irbesartan, one of the stronger structural bridges in this analysis connects Irbesartan with Side effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Irbesartan — Side effects · splits 24 ⟂ 7
Irbesartan — Overview · splits 25 ⟂ 6
Irbesartan — Society and culture · splits 25 ⟂ 6
Irbesartan — History · splits 26 ⟂ 5
Irbesartan — Medical uses · splits 28 ⟂ 3
Irbesartan — Mechanism of action · splits 28 ⟂ 3

Map overview Semantic statistics

Irbesartan

Nodes31
Edges30
Triples52
Avg. degree1.94
Density0.064516
Components1

Source & methodology

TTTA analyzes the structure around Irbesartan to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Irbesartan · EN edition · Analysis: TopicsToTalkAbout

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