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Inositol monophosphatase 1: Clinical significance, Function & Structure

Inositol monophosphatase 1 is an enzyme that in humans is encoded by the IMPA1 gene.

Language: English [EN]
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Inositol monophosphatase 1 topic overview

The analysis highlights Clinical significance, Function and Structure as prominent areas in the source structure around Inositol monophosphatase 1.

Related topics
34
Source areas
5
Connected nodes
39
Extracted relationships
108
Related term clusters
13
Bridge connections
39

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 15 topics
Function · 13 topics
Interacting partners · 2 topics
Overview · 2 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.3.25
↗
3.1.3.94
↗
Aliases
IMPA1, IMP, IMPA, inositol monophosphatase 1, MRT59
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AWB, 1IMA, 1IMB, 1IMC, 1IMD, 1IME, 1IMF, 2HHM, 4AS4
Band
8q21.13 · 3|3 A1
Bgee
secondary oocyte · jejunal mucosa · endothelial cell · mucosa of colon · tibia

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Interacting partners

Clinical significance

For the semantics nerds

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Advanced semantic analysis

How Inositol monophosphatase 1 connects Entity context

The extracted context around Inositol monophosphatase 1 shows recurring relationship patterns in the source. For example, Inositol monophosphatase 1 → cytoplasm, cytosol, hydrolase activity, identical protein binding, inositol biosynthetic process, inositol metabolic process, inositol monophosphate 1-phosphatase activity, inositol monophosphate 3-phosphatase activity, inositol monophosphate 4-phosphatase activity, inositol monophosphate phosphatase activity, inositol phosphate dephosphorylation, inositol phosphate metabolic process, lithium ion binding, magnesium ion binding, manganese ion binding, metal ion binding, phosphate-containing compound metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphate biosynthetic process, protein binding Another extracted example is Inositol monophosphatase 1 → Brodmann area 23, bronchial epithelial cell, ciliary body, conjunctival fornix, endothelial cell, Epithelium of choroid plexus, external carotid artery, facial motor nucleus, iris, jejunal mucosa, motor neuron, mucosa of colon, mucosa of sigmoid colon, Paneth cell, primitive streak, retinal pigment epithelium, right ventricle, secondary oocyte, tibia. Use these groups to spot repeated connection types before inspecting the individual relationships.

Inositol monophosphatase 1

Top relations

Gene ontology · 22
Inositol monophosphatase 1 → cytoplasm, cytosol, hydrolase activity, identical protein binding, inositol biosynthetic process, inositol metabolic process, inositol monophosphate 1-phosphatase activity, inositol monophosphate 3-phosphatase activity, inositol monophosphate 4-phosphatase activity, inositol monophosphate phosphatase activity, inositol phosphate dephosphorylation, inositol phosphate metabolic process, lithium ion binding, magnesium ion binding, manganese ion binding, metal ion binding, phosphate-containing compound metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol phosphate biosynthetic process, protein binding
Bgee · 19
Inositol monophosphatase 1 → Brodmann area 23, bronchial epithelial cell, ciliary body, conjunctival fornix, endothelial cell, Epithelium of choroid plexus, external carotid artery, facial motor nucleus, iris, jejunal mucosa, motor neuron, mucosa of colon, mucosa of sigmoid colon, Paneth cell, primitive streak, retinal pigment epithelium, right ventricle, secondary oocyte, tibia
RNA expression pattern · 19
Inositol monophosphatase 1 → Brodmann area 23, bronchial epithelial cell, ciliary body, conjunctival fornix, endothelial cell, Epithelium of choroid plexus, external carotid artery, facial motor nucleus, iris, jejunal mucosa, motor neuron, mucosa of colon, mucosa of sigmoid colon, Paneth cell, primitive streak, retinal pigment epithelium, right ventricle, secondary oocyte, tibia
related to Structure · 12
Inositol monophosphatase 1 → Asp220, Asp90, Asp93, Glu70, IMPA1, IMPA1's, Inositol, PDB, PF00459, Pfam, Structural, X-ray
related to Function · 3
Inositol monophosphatase 1 → Beyond, IMPA1, Inositol
Band · 2
Inositol monophosphatase 1 → 3|3 A1, 8q21.13
Chr. · 2
Inositol monophosphatase 1 → Chromosome 3 (mouse), Chromosome 8 (human)
End · 2
Inositol monophosphatase 1 → 10,396,499 bp, 81,686,331 bp
3.1.3.25 · 1
Inositol monophosphatase 1 → ↗
3.1.3.94 · 1
Inositol monophosphatase 1 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

inositol impa1 bp human lithium gene chr band enzyme monophosphatase activity chromosome disorder function bipolar external cell location phosphatidylinositol also

Inositol monophosphatase 1 relationships Subject–Predicate–Object triples

TTTA extracted 108 structured relationships around Inositol monophosphatase 1. Examples in this analysis include Inositol monophosphatase 1 → 3.1.3.25 → ↗ and Inositol monophosphatase 1 → Aliases → IMPA1, IMP, IMPA, inositol monophosphatase 1, MRT59. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Inositol monophosphatase 13.1.3.25↗1.00infobox
Inositol monophosphatase 13.1.3.94↗1.00infobox
Inositol monophosphatase 1AliasesIMPA1, IMP, IMPA, inositol monophosphatase 1, MRT591.00infobox
Inositol monophosphatase 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AWB, 1IMA, 1IMB, 1IMC, 1IMD, 1IME, 1IMF, 2HHM, 4AS41.00infobox
Inositol monophosphatase 1Band8q21.131.00infobox
Inositol monophosphatase 1Band3|3 A11.00infobox
Inositol monophosphatase 1Bgeesecondary oocyte1.00infobox
Inositol monophosphatase 1Bgeejejunal mucosa1.00infobox
Inositol monophosphatase 1Bgeeendothelial cell1.00infobox
Inositol monophosphatase 1Bgeemucosa of colon1.00infobox
Inositol monophosphatase 1Bgeetibia1.00infobox
Inositol monophosphatase 1Bgeemucosa of sigmoid colon1.00infobox
Inositol monophosphatase 1Bgeeright ventricle1.00infobox
Inositol monophosphatase 1BgeeBrodmann area 231.00infobox
Inositol monophosphatase 1BgeeEpithelium of choroid plexus1.00infobox
Inositol monophosphatase 1Bgeebronchial epithelial cell1.00infobox
Inositol monophosphatase 1Bgeemotor neuron1.00infobox
Inositol monophosphatase 1Bgeeciliary body1.00infobox
Inositol monophosphatase 1Bgeeretinal pigment epithelium1.00infobox
Inositol monophosphatase 1Bgeeiris1.00infobox
Inositol monophosphatase 1BgeePaneth cell1.00infobox
Inositol monophosphatase 1Bgeefacial motor nucleus1.00infobox
Inositol monophosphatase 1Bgeeconjunctival fornix1.00infobox
Inositol monophosphatase 1Bgeeexternal carotid artery1.00infobox
Inositol monophosphatase 1Bgeeprimitive streak1.00infobox
Inositol monophosphatase 1BioGPSMore reference expression data1.00infobox
Inositol monophosphatase 1Chr.Chromosome 8 (human)1.00infobox
Inositol monophosphatase 1Chr.Chromosome 3 (mouse)1.00infobox
Inositol monophosphatase 1DatabasesNCBI: entry; OMA: entry1.00infobox
Inositol monophosphatase 1End81,686,331 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Inositol monophosphatase 1 bring nearby vocabulary together. In this analysis, examples include Enzyme, Monophosphatase and Impa1. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Inositol monophosphatase 1
    • Enzyme
    • Monophosphatase
    • Impa1
    • Activity
    • Bp
    • Monophosphate
    • Phosphatase
    • Bipolar
    • Disorder
    • Gene
    • Human
    • Lithium
  • inositol monophosphatase 1
    • Human
    • Enzyme
    • Monophosphatase
    • Search
    • Impa1
    • Location
    • Monophosphate
    • Pdb
    • Phosphatase
    • Phosphatidylinositol
    • Structure
    • Activity
  • enzyme
    • Activity
    • Gene
    • Monophosphatase
    • Inositol
    • External
    • Search
    • Impa1
    • Location
    • Monophosphate
    • Phosphatase
    • Bipolar
    • Chromosome
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Monophosphatase
    • End
    • External
    • Mouse
    • Search
    • Impa1
    • Band
  • inositol 1,4,5-trisphosphate
    • Enzyme
    • Monophosphatase
    • Impa1
    • Activity
    • Monophosphate
    • Phosphatase
    • Bipolar
    • Disorder
    • Gene
    • Human
    • Lithium
    • External
  • bipolar disorder
    • Disorder
    • Enzyme
    • Gene
    • Impa1
    • Lithium
    • Inositol
    • 1ima
    • 1imb
    • External
    • Search
    • Enzymes
    • Location
  • inositol
    • Enzyme
    • Monophosphatase
    • Impa1
    • Activity
    • Monophosphate
    • Phosphatase
    • Bipolar
    • Disorder
    • Gene
    • Human
    • Lithium
    • External
  • function
    • External
    • Search
    • Cellular
    • Location
    • Cell
    • Chromosome
    • Activity
    • Bp
    • Chr
    • Gene
    • Human
    • Monophosphatase

Connections between topic areas Semantic bridges

For Inositol monophosphatase 1, one of the stronger structural bridges in this analysis connects Inositol monophosphatase 1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Inositol monophosphatase 1 — Clinical significance · splits 24 ⟂ 16
Inositol monophosphatase 1 — Function · splits 26 ⟂ 14
Inositol monophosphatase 1 — Overview · splits 37 ⟂ 3
Inositol monophosphatase 1 — Structure · splits 37 ⟂ 3
Inositol monophosphatase 1 — Interacting partners · splits 37 ⟂ 3

Map overview Semantic statistics

Inositol monophosphatase 1

Nodes40
Edges39
Triples108
Avg. degree1.95
Density0.05
Components1

Source & methodology

TTTA analyzes the structure around Inositol monophosphatase 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Inositol monophosphatase 1 · EN edition · Analysis: TopicsToTalkAbout

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