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Signal peptide

A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16–30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins that…

Geography, Co-translational versus post-translational translocation & Signal peptide as a therapeutic target

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Co-translational versus post-translational translocation

RibosomeSignal-recognition particleSRP receptorSecBChaperone protein
8 related topics

Signal peptide as a therapeutic target

AntiviralMammarenavirusNMT inhibitorsMyristoylationProteasomal degradation
6 related topics

Function (translocation)

TranslocateProkaryotesPlasma membraneEukaryotesTranslocon
5 related topics

Nucleotide level features

MRNAAdenineMotifsExon
4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

OPM protein
1skh
OPM superfamily
256
Symbol
N/A

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Overview

Function (translocation)

Structure

Co-translational versus post-translational translocation

Nucleotide level features

Alternate secretion mechanisms

Signal peptide as a therapeutic target

Advanced semantic analysis

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Map overview Semantic statistics

Signal peptide

Nodes46
Edges45
Triples61
Avg. degree1.96
Density0.043478
Components1

How this topic connects Entity context

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Signal peptide

Top relations

related to Structure · 11
Signal peptide → At, Because, C-terminus, For, In, Moreover, N-terminus, Nucleus-targeting, Signal, The, This
related to External links · 9
Signal peptide → Archived, Medicine Medical Subject Headings, MeSH, National Library, Peptide, Signal, Signal Peptide DataBase, SPdb, Wayback MachineSignalP
related to Co-translational versus post-translational translocation · 7
Signal peptide → ER, Eukaryotes, In, Once, Ribosomes, SRP, The
related to Alternate secretion mechanisms · 6
Signal peptide → Galectin, In, Interleukin, Proteins, The, UPS
related to Function (translocation) · 6
Signal peptide → Both, In, Sec61, SecYEG, Signal, While
related to Nonclassical sequences · 6
Signal peptide → C-terminal, N-terminal, N-terminus, Signal, Some, The
related to Signal peptide as a therapeutic target · 5
Signal peptide → N-terminus, NMT, Signal, SSPs, The
related to Nucleotide level features · 4
Signal peptide → In, RNA, SSCR, SSCRs
related to Nomenclature · 3
Signal peptide → Signal, These, This
OPM protein · 1
Signal peptide → 1skh

Important terminology Word statistics

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Important terminology

signal peptides peptide proteins protein sequence target translocon n-terminus referred translocation amino present pathway post-translational prokaryotes eukaryotes may acids secreted

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Signal peptideOPM protein1skh1.00infobox
Signal peptideOPM superfamily2561.00infobox
Signal peptideSymbolN/A1.00infobox
Signal peptiderelated to Alternate secretion mechanismsProteins0.60section
Signal peptiderelated to Alternate secretion mechanismsInterleukin0.60section
Signal peptiderelated to Alternate secretion mechanismsGalectin0.60section
Signal peptiderelated to Alternate secretion mechanismsThe0.60section
Signal peptiderelated to Alternate secretion mechanismsUPS0.60section
Signal peptiderelated to Alternate secretion mechanismsIn0.60section
Signal peptiderelated to Co-translational versus post-translational translocationIn0.60section
Signal peptiderelated to Co-translational versus post-translational translocationThe0.60section
Signal peptiderelated to Co-translational versus post-translational translocationSRP0.60section

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