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Hydroxyzine

Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). It is used either by mouth or injection into a muscle.

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3D model (JSmol)
Interactive image
Addiction liability
None-Very Low
AHFS/Drugs.com
Monograph
ATC code
N05BB01 (WHO) N05BB51 (WHO)
Bioavailability
Not known
CAS Number
68-88-2 Y 10246-75-0 (pamoate) · as HCl: 2192-20-3

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Overview

Medical uses

Contraindications

Side effects

Pharmacology

Chemistry

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Hydroxyzine

Nodes122
Edges121
Triples103
Avg. degree1.98
Density0.016393
Components1

How this topic connects Entity context

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Hydroxyzine

Top relations

related to Pharmacokinetics · 18
Hydroxyzine → Although, Cetirizine, CNS, CYP3A4, CYP3A5, Higher, In, It, Its, Metabolites, N-dealkylated, O-dealkylated, One, Overall, The, The N-dealykylated, These, Tmax
related to Brand names · 13
Hydroxyzine → Alamon, Atarax, Aterax, Durrax, Equipose, Masmoran, Orgatrax, Paxistil, Quiess, The, Tran-Q, Tranquizine, Vistaril
related to Pharmacodynamics · 10
Hydroxyzine → D2, H1, HT2A, Hydroxyzine's, In, Other, PET, Similarly, This, Unlike
has effect · 7
Hydroxyzine → Central, CNS, Gastrointestinal, Several, Such, The, While
Legal status · 6
Hydroxyzine → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, SE: Rx-only, UK: POM (Prescription only), US: ℞-only
CAS Number · 2
Hydroxyzine → 68-88-2 Y 10246-75-0 (pamoate), as HCl: 2192-20-3
ChEBI · 2
Hydroxyzine → as HCl: CHEBI:5819, CHEBI:5818 Y
ChEMBL · 2
Hydroxyzine → as HCl: ChEMBL3186993, ChEMBL896 Y
ChemSpider · 2
Hydroxyzine → 3531 Y, as HCl: 82634
DrugBank · 2
Hydroxyzine → as HCl: DBSALT000343, DB00557 Y

Important terminology Word statistics

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Important terminology

effects antihistamine also administration use side elimination pamoate treatment include drug half-life adults hours due used mouth anxiety studies nervous

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Hydroxyzine3D model (JSmol)Interactive image1.00infobox
HydroxyzineAddiction liabilityNone-Very Low1.00infobox
HydroxyzineAHFS/Drugs.comMonograph1.00infobox
HydroxyzineATC codeN05BB01 (WHO) N05BB51 (WHO)1.00infobox
HydroxyzineBioavailabilityNot known1.00infobox
HydroxyzineCAS Number68-88-2 Y 10246-75-0 (pamoate)1.00infobox
HydroxyzineCAS Numberas HCl: 2192-20-31.00infobox
HydroxyzineChEBICHEBI:5818 Y1.00infobox
HydroxyzineChEBIas HCl: CHEBI:58191.00infobox
HydroxyzineChEMBLChEMBL896 Y1.00infobox
HydroxyzineChEMBLas HCl: ChEMBL31869931.00infobox
HydroxyzineChemSpider3531 Y1.00infobox
HydroxyzineChemSpideras HCl: 826341.00infobox
HydroxyzineCompTox Dashboard (EPA)DTXSID80231371.00infobox
HydroxyzineDependence liabilityVery Low1.00infobox
HydroxyzineDrug classFirst-generation antihistamine; Sedative; Anxiolytic1.00infobox
HydroxyzineDrugBankDB00557 Y1.00infobox
HydroxyzineDrugBankas HCl: DBSALT0003431.00infobox
HydroxyzineECHA InfoCard100.000.6301.00infobox
HydroxyzineElimination half-lifeAdults: 20.0 hours Elderly: 29.3 hours Children: 7.1 hours1.00infobox
HydroxyzineExcretionUrine, feces1.00infobox
HydroxyzineFormulaC21H27ClN2O21.00infobox
HydroxyzineIUPHAR/BPS71991.00infobox
HydroxyzineKEGGD08054 Y1.00infobox
HydroxyzineKEGGas HCl: D006721.00infobox
HydroxyzineLegal statusAU: S4 (Prescription only)1.00infobox
HydroxyzineLegal statusCA: ℞-only1.00infobox
HydroxyzineLegal statusUK: POM (Prescription only)1.00infobox
HydroxyzineLegal statusUS: ℞-only1.00infobox
HydroxyzineLegal statusEU: Rx-only1.00infobox

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