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Humanin is a micropeptide encoded in the mitochondrial genome by the 16S ribosomal RNA gene, MT-RNR2. Its structure contains a three-turn α-helix, and no symmetry.
The analysis highlights Research, Other species and Function as prominent areas in the source structure around Humanin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Humanin shows recurring relationship patterns in the source. For example, Humanin → apoptotic process, cellular iron ion homeostasis, cytoplasm, extracellular negative regulation of signal transduction, extracellular region, G protein-coupled receptor signaling pathway, leukocyte chemotaxis, mitochondrion, negative regulation of apoptotic process, negative regulation of execution phase of apoptosis, negative regulation of signaling receptor activity, perinuclear region of cytoplasm, protein binding, receptor antagonist activity, signaling receptor binding Another extracted example is Humanin → Alzheimer's, Bax, Bcl-2-associated, IGFBP3, Nishimoto, The, The Pinchas Cohen, The Reed. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
effects found peptide amino mitochondrial gene also neuroprotective peptides alzheimer's disease activity 16s protein sequence genome models cytoprotective mt-rnr2 encoded
TTTA extracted 76 structured relationships around Humanin. Examples in this analysis include Humanin → Aliases → RNR2, mitochondrially encoded 16S RNA, MTRNR2 and Humanin → Available structures → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1Y32, 2GD3, 5GIW. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Humanin | Aliases | RNR2, mitochondrially encoded 16S RNA, MTRNR2 | 1.00 | infobox |
| Humanin | Available structures | Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1Y32, 2GD3, 5GIW | 1.00 | infobox |
| Humanin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Humanin | Ensembl | ENSG00000210082 | 1.00 | infobox |
| Humanin | Entrez | 4550 | 1.00 | infobox |
| Humanin | External IDs | OMIM: 561010; MGI: 102492; GeneCards: RNR2 | 1.00 | infobox |
| Humanin | Gene ontology | signaling receptor binding | 1.00 | infobox |
| Humanin | Gene ontology | protein binding | 1.00 | infobox |
| Humanin | Gene ontology | receptor antagonist activity | 1.00 | infobox |
| Humanin | Gene ontology | cytoplasm | 1.00 | infobox |
| Humanin | Gene ontology | perinuclear region of cytoplasm | 1.00 | infobox |
| Humanin | Gene ontology | extracellular region | 1.00 | infobox |
| Humanin | Gene ontology | mitochondrion | 1.00 | infobox |
| Humanin | Gene ontology | negative regulation of apoptotic process | 1.00 | infobox |
| Humanin | Gene ontology | leukocyte chemotaxis | 1.00 | infobox |
| Humanin | Gene ontology | cellular iron ion homeostasis | 1.00 | infobox |
| Humanin | Gene ontology | apoptotic process | 1.00 | infobox |
| Humanin | Gene ontology | extracellular negative regulation of signal transduction | 1.00 | infobox |
| Humanin | Gene ontology | G protein-coupled receptor signaling pathway | 1.00 | infobox |
| Humanin | Gene ontology | negative regulation of execution phase of apoptosis | 1.00 | infobox |
| Humanin | Gene ontology | negative regulation of signaling receptor activity | 1.00 | infobox |
| Humanin | List of PDB id codes | List of PDB id codes1Y32, 2GD3, 5GIW | 1.00 | infobox |
| Humanin | Location (UCSC) | n/a | 1.00 | infobox |
| Humanin | Orthologs | OrthologsDatabasesNCBI: entry; OMA: entrySpeciesHumanMouseEntrez455017725EnsemblENSG00000210082ENSMUSG00000064339UniProtQ8IVG9n/aRefSeq (mRNA)n/an/aRefSeq (protein)n/an/aLocatio… | 1.00 | infobox |
| Humanin | PDB | Human UniProt search: PDBe RCSB | 1.00 | infobox |
| Humanin | RefSeq (mRNA) | n/a | 1.00 | infobox |
| Humanin | RefSeq (protein) | n/a | 1.00 | infobox |
| Humanin | Species | Human | 1.00 | infobox |
| Humanin | UniProt | Q8IVG9 | 1.00 | infobox |
| Humanin | is a | micropeptide encoded in the mitochondrial genome by the 16S ribosomal RNA gene | 0.90 | text |
The concept neighborhoods around Humanin bring nearby vocabulary together. In this analysis, examples include Effects, Alzheimer's and Disease. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Humanin, one of the stronger structural bridges in this analysis connects Humanin with Other species. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Humanin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research, Other species & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Humanin · EN edition · Analysis: TopicsToTalkAbout