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HSPA4: Interactions & Overview

Heat shock 70 kDa protein 4 is a protein that in humans is encoded by the HSPA4 gene.

Language: English [EN]
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HSPA4 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around HSPA4.

Related topics
13
Source areas
2
Connected nodes
15
Extracted relationships
81
Concept neighborhoods
6
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 10 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
HSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 4
Band
5q31.1 · 11 B1.3|11 31.91 cM
Bgee
gonad · gingival epithelium · islet of Langerhans · right testis · left testis
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HSPA4 connects Entity context

The extracted context around HSPA4 shows recurring relationship patterns in the source. For example, HSPA4 → amniotic fluid, endothelial cell of lymphatic vessel, epiblast, genital tubercle, gingival epithelium, gonad, Ileal epithelium, islet of Langerhans, left testis, mucosa of pharynx, otic placode, otic vesicle, primitive streak, right testis, saccule, stromal cell of endometrium, tail of embryo, tendon of biceps brachii, tonsil, trigeminal ganglion Another extracted example is HSPA4 → ATP binding, chaperone-mediated protein complex assembly, cytoplasm, cytosol, extracellular exosome, nucleotide binding, nucleus, protein binding, protein insertion into mitochondrial outer membrane, response to unfolded protein. Use these groups to spot repeated connection types before inspecting the individual relationships.

HSPA4

Top relations

Bgee · 20
HSPA4 → amniotic fluid, endothelial cell of lymphatic vessel, epiblast, genital tubercle, gingival epithelium, gonad, Ileal epithelium, islet of Langerhans, left testis, mucosa of pharynx, otic placode, otic vesicle, primitive streak, right testis, saccule, stromal cell of endometrium, tail of embryo, tendon of biceps brachii, tonsil, trigeminal ganglion
RNA expression pattern · 20
HSPA4 → amniotic fluid, endothelial cell of lymphatic vessel, epiblast, genital tubercle, gingival epithelium, gonad, Ileal epithelium, islet of Langerhans, left testis, mucosa of pharynx, otic placode, otic vesicle, primitive streak, right testis, saccule, stromal cell of endometrium, tail of embryo, tendon of biceps brachii, tonsil, trigeminal ganglion
Gene ontology · 10
HSPA4 → ATP binding, chaperone-mediated protein complex assembly, cytoplasm, cytosol, extracellular exosome, nucleotide binding, nucleus, protein binding, protein insertion into mitochondrial outer membrane, response to unfolded protein
related to Interactions · 7
HSPA4 → APAF1DNAJB1, HDAC1, Histone, HSF1, HSPBP1, NAD, STUB1
related to External links · 3
HSPA4 → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
HSPA4 → 11 B1.3|11 31.91 cM, 5q31.1
Chr. · 2
HSPA4 → Chromosome 11 (mouse), Chromosome 5 (human)
End · 2
HSPA4 → 133,106,449 bp, 53,191,284 bp
Aliases · 1
HSPA4 → HSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 4
BioGPS · 1
HSPA4 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein human gene bp chr band chromosome mouse heat shock member family location 70 encoded apg-2 external 106 449 end

HSPA4 relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around HSPA4. Examples in this analysis include HSPA4 → Aliases → HSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 4 and HSPA4 → Band → 5q31.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HSPA4AliasesHSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY, heat shock protein family A (Hsp70) member 41.00infobox
HSPA4Band5q31.11.00infobox
HSPA4Band11 B1.3|11 31.91 cM1.00infobox
HSPA4Bgeegonad1.00infobox
HSPA4Bgeegingival epithelium1.00infobox
HSPA4Bgeeislet of Langerhans1.00infobox
HSPA4Bgeeright testis1.00infobox
HSPA4Bgeeleft testis1.00infobox
HSPA4Bgeemucosa of pharynx1.00infobox
HSPA4Bgeestromal cell of endometrium1.00infobox
HSPA4Bgeeamniotic fluid1.00infobox
HSPA4Bgeetendon of biceps brachii1.00infobox
HSPA4Bgeetonsil1.00infobox
HSPA4Bgeeotic placode1.00infobox
HSPA4Bgeesaccule1.00infobox
HSPA4Bgeetail of embryo1.00infobox
HSPA4Bgeegenital tubercle1.00infobox
HSPA4Bgeeotic vesicle1.00infobox
HSPA4Bgeeprimitive streak1.00infobox
HSPA4Bgeeepiblast1.00infobox
HSPA4BgeeIleal epithelium1.00infobox
HSPA4Bgeetrigeminal ganglion1.00infobox
HSPA4Bgeeendothelial cell of lymphatic vessel1.00infobox
HSPA4BioGPSMore reference expression data1.00infobox
HSPA4Chr.Chromosome 5 (human)1.00infobox
HSPA4Chr.Chromosome 11 (mouse)1.00infobox
HSPA4DatabasesNCBI: entry; OMA: entry1.00infobox
HSPA4End133,106,449 bp1.00infobox
HSPA4End53,191,284 bp1.00infobox
HSPA4EnsemblENSG000001706061.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around HSPA4 bring nearby vocabulary together. In this analysis, examples include Protein, Human and Apg-2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HSPA4
    • Protein
    • Human
    • Apg-2
    • Family
    • Location
    • Member
    • Mouse
    • Shock
    • Chromosome
    • Bp
    • Chr
    • Equivalent
  • hspa4
    • Protein
    • Human
    • Apg-2
    • Family
    • Location
    • Member
    • Mouse
    • Shock
    • Chromosome
    • Bp
    • Chr
    • Equivalent
  • protein
    • Hspa4
    • Family
    • Human
    • Member
    • Shock
    • Apg-2
    • Location
    • Mouse
    • Chromosome
    • Bp
    • Chr
    • Equivalent
  • gene
    • Heat
    • Location
    • Shock
    • Protein
    • Chromosome
    • Bp
    • Chr
    • Hspa4
    • B1
    • End
    • Human
    • Family
  • heat shock protein 70
    • Shock
    • Hspa4
    • Encoded
    • Gene
    • Family
    • Human
    • Member
    • Protein
    • Apg-2
    • External
    • Humans
    • Interactions
  • interactions
    • External
    • Reading
    • References
    • Location
    • Member
    • Shock
    • Chromosome
    • Bp
    • Chr
    • Protein

Connections between topic areas Semantic bridges

For HSPA4, one of the stronger structural bridges in this analysis connects HSPA4 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HSPA4Interactions · splits 5 ⟂ 11
HSPA4Overview · splits 12 ⟂ 4

Map overview Semantic statistics

HSPA4

Nodes16
Edges15
Triples81
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around HSPA4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HSPA4 · EN edition · Analysis: TopicsToTalkAbout

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