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HMOX2: Function & Overview

Heme oxygenase 2 is an enzyme that in humans is encoded by the HMOX2 gene.

Language: English [EN]
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HMOX2 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around HMOX2.

Related topics
9
Source areas
2
Connected nodes
11
Extracted relationships
85
Concept neighborhoods
7
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 7 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.14.18
Aliases
HMOX2, HO-2, heme oxygenase 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2Q32, 2QPP, 2RGZ, 4WMH
Band
16p13.3 · 16 A1|16 2.46 cM
Bgee
right testis · left testis · prefrontal cortex · left ventricle · apex of heart
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HMOX2 connects Entity context

The extracted context around HMOX2 shows recurring relationship patterns in the source. For example, HMOX2 → anterior horn of spinal cord, apex of heart, body of stomach, Brodmann area 9, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, external carotid artery, facial motor nucleus, internal carotid artery, left testis, left ventricle, nucleus accumbens, prefrontal cortex, right auricle of heart, right testis, seminiferous tubule, spermatid, stroma of bone marrow, superior frontal gyrus, supraoptic nucleus Another extracted example is HMOX2 → cellular iron ion homeostasis, endoplasmic reticulum, endoplasmic reticulum membrane, heme binding, heme catabolic process, heme oxidation, heme oxygenase (decyclizing) activity, intracellular membrane-bounded organelle, iron ion homeostasis, membrane, metal ion binding, neutrophil degranulation, oxidoreductase activity, plasma membrane, protein binding, response to hypoxia, response to oxidative stress, specific granule membrane. Use these groups to spot repeated connection types before inspecting the individual relationships.

HMOX2

Top relations

Bgee · 20
HMOX2 → anterior horn of spinal cord, apex of heart, body of stomach, Brodmann area 9, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, external carotid artery, facial motor nucleus, internal carotid artery, left testis, left ventricle, nucleus accumbens, prefrontal cortex, right auricle of heart, right testis, seminiferous tubule, spermatid, stroma of bone marrow, superior frontal gyrus, supraoptic nucleus
RNA expression pattern · 20
HMOX2 → anterior horn of spinal cord, apex of heart, body of stomach, Brodmann area 9, dentate gyrus of hippocampal formation granule cell, endothelial cell of lymphatic vessel, external carotid artery, facial motor nucleus, internal carotid artery, left testis, left ventricle, nucleus accumbens, prefrontal cortex, right auricle of heart, right testis, seminiferous tubule, spermatid, stroma of bone marrow, superior frontal gyrus, supraoptic nucleus
Gene ontology · 18
HMOX2 → cellular iron ion homeostasis, endoplasmic reticulum, endoplasmic reticulum membrane, heme binding, heme catabolic process, heme oxidation, heme oxygenase (decyclizing) activity, intracellular membrane-bounded organelle, iron ion homeostasis, membrane, metal ion binding, neutrophil degranulation, oxidoreductase activity, plasma membrane, protein binding, response to hypoxia, response to oxidative stress, specific granule membrane
Band · 2
HMOX2 → 16 A1|16 2.46 cM, 16p13.3
Chr. · 2
HMOX2 → Chromosome 16 (human), Chromosome 16 (mouse)
End · 2
HMOX2 → 4,510,347 bp, 4,584,606 bp
related to Function · 2
HMOX2 → Heme, HMOX1
1.14.14.18 · 1
HMOX2 → ↗
Aliases · 1
HMOX2 → HMOX2, HO-2, heme oxygenase 2
Available structures · 1
HMOX2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2Q32, 2QPP, 2RGZ, 4WMH

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

heme oxygenase bp chr human band gene chromosome 16 enzyme location activity mouse function external search bpend4 510 347 end

HMOX2 relationships Subject–Predicate–Object triples

TTTA extracted 85 structured relationships around HMOX2. Examples in this analysis include HMOX2 → 1.14.14.18 → ↗ and HMOX2 → Aliases → HMOX2, HO-2, heme oxygenase 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HMOX21.14.14.181.00infobox
HMOX2AliasesHMOX2, HO-2, heme oxygenase 21.00infobox
HMOX2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2Q32, 2QPP, 2RGZ, 4WMH1.00infobox
HMOX2Band16p13.31.00infobox
HMOX2Band16 A1|16 2.46 cM1.00infobox
HMOX2Bgeeright testis1.00infobox
HMOX2Bgeeleft testis1.00infobox
HMOX2Bgeeprefrontal cortex1.00infobox
HMOX2Bgeeleft ventricle1.00infobox
HMOX2Bgeeapex of heart1.00infobox
HMOX2Bgeesuperior frontal gyrus1.00infobox
HMOX2BgeeBrodmann area 91.00infobox
HMOX2Bgeeright auricle of heart1.00infobox
HMOX2Bgeenucleus accumbens1.00infobox
HMOX2Bgeebody of stomach1.00infobox
HMOX2Bgeespermatid1.00infobox
HMOX2Bgeeseminiferous tubule1.00infobox
HMOX2Bgeefacial motor nucleus1.00infobox
HMOX2Bgeeanterior horn of spinal cord1.00infobox
HMOX2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
HMOX2Bgeesupraoptic nucleus1.00infobox
HMOX2Bgeestroma of bone marrow1.00infobox
HMOX2Bgeeendothelial cell of lymphatic vessel1.00infobox
HMOX2Bgeeexternal carotid artery1.00infobox
HMOX2Bgeeinternal carotid artery1.00infobox
HMOX2BioGPSMore reference expression data1.00infobox
HMOX2Chr.Chromosome 16 (human)1.00infobox
HMOX2Chr.Chromosome 16 (mouse)1.00infobox
HMOX2DatabasesNCBI: entry; OMA: entry1.00infobox
HMOX2End4,510,347 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around HMOX2 bring nearby vocabulary together. In this analysis, examples include Oxygenase, External and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • enzyme
    • Hmox2
    • Heme
    • Oxygenase
    • Gene
    • External
    • Function
    • Search
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
  • heme oxygenase
    • Oxygenase
    • Enzyme
    • Hmox2
    • Activity
    • Gene
    • External
    • Function
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
  • heme
    • Oxygenase
    • Enzyme
    • Hmox2
    • Activity
    • Gene
    • External
    • Function
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
  • gene
    • Location
    • Chromosome
    • Hmox2
    • Human
    • A1
    • Bp
    • Bpend4
    • Chr
    • End
    • External
    • Function
    • Mouse
  • function
    • External
    • Search
    • Activity
    • Location
    • Chromosome
    • Gene
    • Hmox2
    • Human
    • Reading
    • References
    • Bp
    • Chr
  • HMOX2
    • Oxygenase
    • External
    • Function
    • Search
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Reading
  • hmox2
    • Oxygenase
    • External
    • Function
    • Search
    • Activity
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Reading

Connections between topic areas Semantic bridges

For HMOX2, one of the stronger structural bridges in this analysis connects HMOX2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HMOX2Function · splits 4 ⟂ 8
HMOX2Overview · splits 9 ⟂ 3

Map overview Semantic statistics

HMOX2

Nodes12
Edges11
Triples85
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around HMOX2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HMOX2 · EN edition · Analysis: TopicsToTalkAbout

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