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Histatin

Histatins are a family of histidine-rich (cationic) antimicrobial proteins found in saliva. Histatin's involvement in antimicrobial activities makes histatin part of the innate immune system. Histatin was first discovered (isolated) in 1988, with functions that are responsible in keeping homeostasis inside the oral cavity, helping in the formation of…

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Overview

Structure

Function

Histatin 5

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Map overview Semantic statistics

Histatin

Nodes44
Edges43
Triples38
Avg. degree1.95
Density0.045455
Components1

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Histatin

Top relations

related to Structure · 9
Histatin → An, Histatins, HTN1, HTN3, Nonetheless, P15515, Studies, The, UniProt ID
related to Function · 7
Histatin → Ebner's, Here, Histatins, HTN1, HTN3, The, Therefore
related to Antifungal activity · 6
Histatin → As, Candida, Enamel, Moreover, ROS, This
related to Cell migration · 4
Histatin → By, Histatins, Rac1 GTPase, RIN2/Rab5
related to Histatin 5 · 3
Histatin → An, ATP, The
related to Wound healing · 3
Histatin → ERK1/2, Histatins, They
part of · 1
Histatin → the innate immune system

Important terminology Word statistics

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Important terminology

histatins cell antifungal antimicrobial oral activity migration found amino species cationic protein htn3 structure function wound saliva acids enamel cells

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Histatinpart ofthe innate immune system0.85text
Candida glabratainstance ofby binding to the potassium transporter and facilitating in the loss of azole-resistant species.The antifungal properties of histatins have been seen with fungi0.80text
Candida kruseiinstance ofby binding to the potassium transporter and facilitating in the loss of azole-resistant species.The antifungal properties of histatins have been seen with fungi0.80text
Saccharomyces cerevisiaeinstance ofby binding to the potassium transporter and facilitating in the loss of azole-resistant species.The antifungal properties of histatins have been seen with fungi0.80text
and Cryptococcus neoformans.Histatins also precipitate tannins from solutioninstance ofby binding to the potassium transporter and facilitating in the loss of azole-resistant species.The antifungal properties of histatins have been seen with fungi0.80text
thus preventing alimentary adsorptioninstance ofby binding to the potassium transporter and facilitating in the loss of azole-resistant species.The antifungal properties of histatins have been seen with fungi0.80text
Histatinrelated to Antifungal activityCandida0.60section
Histatinrelated to Antifungal activityROS0.60section
Histatinrelated to Antifungal activityThis0.60section
Histatinrelated to Antifungal activityAs0.60section
Histatinrelated to Antifungal activityMoreover0.60section
Histatinrelated to Antifungal activityEnamel0.60section

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