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The heteronuclear single quantum coherence or heteronuclear single quantum correlation experiment, normally abbreviated as HSQC, is used frequently in NMR spectroscopy of organic molecules and is of particular significance in the field of protein NMR. The experiment was first described by Geoffrey Bodenhausen and D. J. Ruben in 1980. The resulting…
The analysis highlights Art, HSQC in protein NMR and General scheme as prominent areas in the source structure around Heteronuclear single quantum coherence spectroscopy.
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hsqc protein nmr experiment 15n spectrum 1h peaks normally proton 13c also peak attached experiments used usually 31p residue structure
TTTA extracted 7 structured relationships around Heteronuclear single quantum coherence spectroscopy. Examples in this analysis include 1H → instance of → but is also applicable to other nuclei and structure determination → instance of → The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| 1H | instance of | but is also applicable to other nuclei | 0.80 | text |
| structure determination | instance of | The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments | 0.80 | text |
| relaxation analysis.Chemicals labelled with 15N isotope are relatively inexpensive | instance of | The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments | 0.80 | text |
| and the 15N HSQC is a sensitive experiment whereby a spectrum can be acquired in a relatively short time | instance of | The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments | 0.80 | text |
| the 15N HSQC is therefore often used to screen candidates for their suitability for structure determination by NMR | instance of | The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments | 0.80 | text |
| as well as optimization of the sample conditions | instance of | The assignment of the spectrum is essential for a meaningful interpretation of more advanced NMR experiments | 0.80 | text |
| drugs | instance of | as well the interactions with ligands | 0.80 | text |
The concept neighborhoods around Heteronuclear single quantum coherence spectroscopy bring nearby vocabulary together. In this analysis, examples include Protein, Structure and 15n. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Heteronuclear single quantum coherence spectroscopy, one of the stronger structural bridges in this analysis connects Heteronuclear single quantum coherence spectroscopy with HSQC in protein NMR. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Heteronuclear single quantum coherence spectroscopy to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, HSQC in protein NMR & General scheme, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Heteronuclear single quantum coherence spectroscopy · EN edition · Analysis: TopicsToTalkAbout