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DNA gyrase

DNA gyrase, or simply gyrase, is an enzyme within the class of topoisomerase and is a subclass of Type II topoisomerases that reduces topological strain in an ATP dependent manner while double-stranded DNA is being unwound by elongating RNA-polymerase or by helicase in front of the progressing replication fork. It is the only known enzyme to actively…

Standards, Overview & Inhibition by antibiotics

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Key facts & relationships

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BRENDA
enzyme data
EC no.
5.6.2.2
ExPASy
NiceZyme view
KEGG
enzyme entry
MetaCyc
metabolic pathway
NCBI
proteins

Topics to explore

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Overview

Mechanochemical model of gyrase activity

Gyrase specificity

Inhibition by antibiotics

Phage T4

Advanced semantic analysis

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Map overview Semantic statistics

DNA gyrase

Nodes45
Edges44
Triples64
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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DNA gyrase

Top relations

related to Gyrase specificity · 15
DNA gyrase → AT-rich, C-terminal, DNA, Escherichia, GC-rich, GyrA, Gyrase, It, Mu, Recently, SGS, SGSs, Strong, The, Topo-Seq
related to Gyrase structure · 11
DNA gyrase → ATP, ATPase, Binding, C-gates, DNA, DNA-gates, GyrA, GyrB, Hydrolysis, N-gates, Structurally
related to Inhibition by antibiotics · 11
DNA gyrase → ATPase, By, Coumermycin A1, DNA, G-segment, Gyrase, GyrB, Quinolone-resistant, The, This, Two
related to External links · 6
DNA gyrase → APDBe-KB P0A2I3, DNA, Escherichia, PDB, PDBe-KB P0AES4, Salmonella
related to Phage T4 · 5
DNA gyrase → DNA, Mutants, Phage T4, Since, The
BRENDA · 1
DNA gyrase → enzyme data
EC no. · 1
DNA gyrase → 5.6.2.2
ExPASy · 1
DNA gyrase → NiceZyme view
KEGG · 1
DNA gyrase → enzyme entry
MetaCyc · 1
DNA gyrase → metabolic pathway

Important terminology Word statistics

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Important terminology

dna gyrase atp supercoils enzyme replication antibiotics binding two positive phage also bacterial subunits molecules subunit negative ability topoisomerase gyra

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DNA gyraseBRENDAenzyme data1.00infobox
DNA gyraseEC no.5.6.2.21.00infobox
DNA gyraseExPASyNiceZyme view1.00infobox
DNA gyraseKEGGenzyme entry1.00infobox
DNA gyraseMetaCycmetabolic pathway1.00infobox
DNA gyraseNCBIproteins1.00infobox
DNA gyrasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
DNA gyrasePMCarticles1.00infobox
DNA gyrasePubMedarticles1.00infobox
DNA gyraseRheareactions1.00infobox
DNA gyraseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox
DNA gyraseis atarget of many antibiotics0.90text

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    Min side: 3
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