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GPR35

G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.

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Aliases
GPR35, G protein-coupled receptor 35
Band
2q37.3 · 1|1 D
Bgee
mucosa of transverse colon · mucosa of ileum · duodenum · jejunal mucosa · granulocyte
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 1 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Ligands

Clinical significance

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Map overview Semantic statistics

GPR35

Nodes37
Edges36
Triples87
Avg. degree1.95
Density0.054054
Components1

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GPR35

Top relations

Bgee · 19
GPR35 → body of stomach, colon, duodenum, esophagus, granulocyte, jejunal mucosa, lumbar spinal ganglion, monocyte, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, neural layer of retina, primary oocyte, rectum, right uterine tube, secondary oocyte, urethra, yolk sac, zygote
RNA expression pattern · 19
GPR35 → body of stomach, colon, duodenum, esophagus, granulocyte, jejunal mucosa, lumbar spinal ganglion, monocyte, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, neural layer of retina, primary oocyte, rectum, right uterine tube, secondary oocyte, urethra, yolk sac, zygote
Gene ontology · 16
GPR35 → C-X-C chemokine receptor activity, chemokine-mediated signaling pathway, cytoskeleton organization, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of neuronal action potential, negative regulation of voltage-gated calcium channel activity, plasma membrane, positive regulation of cytosolic calcium ion concentration, positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway, positive regulation of Rho protein signal transduction, signal transducer activity, signal transduction
related to Antagonists · 5
GPR35 → Antagonists, CID-1542103, CID-2286812, ML144, ML145
related to Endogenous ligands · 4
GPR35 → All, Although GPR35, T3, The
Band · 2
GPR35 → 1|1 D, 2q37.3
Chr. · 2
GPR35 → Chromosome 1 (mouse), Chromosome 2 (human)
End · 2
GPR35 → 240,633,159 bp, 92,914,113 bp
related to Clinical significance · 2
GPR35 → Deletion, In
Aliases · 1
GPR35 → GPR35, G protein-coupled receptor 35

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Important terminology

bp human gene chr band receptor chromosome protein-coupled location agonists mouse 35 expression known 633 159 end 240 914 113

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GPR35AliasesGPR35, G protein-coupled receptor 351.00infobox
GPR35Band2q37.31.00infobox
GPR35Band1|1 D1.00infobox
GPR35Bgeemucosa of transverse colon1.00infobox
GPR35Bgeemucosa of ileum1.00infobox
GPR35Bgeeduodenum1.00infobox
GPR35Bgeejejunal mucosa1.00infobox
GPR35Bgeegranulocyte1.00infobox
GPR35Bgeeright uterine tube1.00infobox
GPR35Bgeemonocyte1.00infobox
GPR35Bgeerectum1.00infobox
GPR35Bgeebody of stomach1.00infobox
GPR35Bgeemucosa of sigmoid colon1.00infobox
GPR35Bgeezygote1.00infobox
GPR35Bgeelumbar spinal ganglion1.00infobox
GPR35Bgeeprimary oocyte1.00infobox
GPR35Bgeesecondary oocyte1.00infobox
GPR35Bgeeneural layer of retina1.00infobox
GPR35Bgeeurethra1.00infobox
GPR35Bgeeesophagus1.00infobox
GPR35Bgeeyolk sac1.00infobox
GPR35Bgeecolon1.00infobox
GPR35BioGPSMore reference expression data1.00infobox
GPR35Chr.Chromosome 2 (human)1.00infobox
GPR35Chr.Chromosome 1 (mouse)1.00infobox
GPR35DatabasesNCBI: entry; OMA: entry1.00infobox
GPR35End240,633,159 bp1.00infobox
GPR35End92,914,113 bp1.00infobox
GPR35EnsemblENSG000001786231.00infobox
GPR35Entrez28591.00infobox

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