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G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
The analysis highlights Ligands, Clinical significance and Overview as prominent areas in the source structure around GPR35.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around GPR35 shows recurring relationship patterns in the source. For example, GPR35 → body of stomach, colon, duodenum, esophagus, granulocyte, jejunal mucosa, lumbar spinal ganglion, monocyte, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, neural layer of retina, primary oocyte, rectum, right uterine tube, secondary oocyte, urethra, yolk sac, zygote Another extracted example is GPR35 → C-X-C chemokine receptor activity, chemokine-mediated signaling pathway, cytoskeleton organization, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, membrane, negative regulation of neuronal action potential, negative regulation of voltage-gated calcium channel activity, plasma membrane, positive regulation of cytosolic calcium ion concentration, positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway, positive regulation of Rho protein signal transduction, signal transducer activity, signal transduction. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp human gene chr band receptor chromosome protein-coupled location agonists mouse 35 expression known 633 159 end 240 914 113
TTTA extracted 83 structured relationships around GPR35. Examples in this analysis include GPR35 → Aliases → GPR35, G protein-coupled receptor 35 and GPR35 → Band → 2q37.3. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| GPR35 | Aliases | GPR35, G protein-coupled receptor 35 | 1.00 | infobox |
| GPR35 | Band | 2q37.3 | 1.00 | infobox |
| GPR35 | Band | 1|1 D | 1.00 | infobox |
| GPR35 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| GPR35 | Bgee | mucosa of ileum | 1.00 | infobox |
| GPR35 | Bgee | duodenum | 1.00 | infobox |
| GPR35 | Bgee | jejunal mucosa | 1.00 | infobox |
| GPR35 | Bgee | granulocyte | 1.00 | infobox |
| GPR35 | Bgee | right uterine tube | 1.00 | infobox |
| GPR35 | Bgee | monocyte | 1.00 | infobox |
| GPR35 | Bgee | rectum | 1.00 | infobox |
| GPR35 | Bgee | body of stomach | 1.00 | infobox |
| GPR35 | Bgee | mucosa of sigmoid colon | 1.00 | infobox |
| GPR35 | Bgee | zygote | 1.00 | infobox |
| GPR35 | Bgee | lumbar spinal ganglion | 1.00 | infobox |
| GPR35 | Bgee | primary oocyte | 1.00 | infobox |
| GPR35 | Bgee | secondary oocyte | 1.00 | infobox |
| GPR35 | Bgee | neural layer of retina | 1.00 | infobox |
| GPR35 | Bgee | urethra | 1.00 | infobox |
| GPR35 | Bgee | esophagus | 1.00 | infobox |
| GPR35 | Bgee | yolk sac | 1.00 | infobox |
| GPR35 | Bgee | colon | 1.00 | infobox |
| GPR35 | BioGPS | More reference expression data | 1.00 | infobox |
| GPR35 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| GPR35 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| GPR35 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| GPR35 | End | 240,633,159 bp | 1.00 | infobox |
| GPR35 | End | 92,914,113 bp | 1.00 | infobox |
| GPR35 | Ensembl | ENSG00000178623 | 1.00 | infobox |
| GPR35 | Entrez | 2859 | 1.00 | infobox |
The concept neighborhoods around GPR35 bring nearby vocabulary together. In this analysis, examples include Gene, Agonists and Protein-coupled. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For GPR35, one of the stronger structural bridges in this analysis connects GPR35 with Ligands. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around GPR35 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Ligands, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — GPR35 · EN edition · Analysis: TopicsToTalkAbout
