Gitelman syndrome

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around Gitelman syndrome. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Signs and symptoms

Diuretics Low levels of chloride Gordon's syndrome Cramps Waking up at night to urinate

15 related topics

Diagnosis

Genetic testing Introns Proton-pump inhibitors Aminoglycosides Primary aldosteronism

13 related topics

Treatment

Potassium Magnesium Diarrhea Aldosterone Spironolactone

8 related topics

History

Nephrologist University of North Carolina School of Medicine

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Causes: Mutations in SLC12A3, CLCNKB, MT-TI, MT-TF
Other names: Primary renal tubular hypokalemic hypomagnesemia with hypocalciuria
Specialty: Nephrology

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Autosomal recessive Dominance (genetics)
Low blood levels of potassium Hypokalemia
Magnesium Hypomagnesemia
Decreased excretion of calcium in the urine Hypocalciuria
Elevated blood pH Metabolic alkalosis
Variants Variant (biology)
Alleles Allele
Gene
Thiazide
Sodium-chloride cotransporter Sodium-chloride symporter
Distal convoluted tubule
Kidney
Sodium
Chloride
Bartter syndrome

Signs and symptoms

Diuretics
Low levels of chloride Hypochloremia
Gordon's syndrome Pseudohypoaldosteronism
Cramps Cramp
Waking up at night to urinate Nocturia
Abnormal sensations Paresthesias
Chondrocalcinosis
Seizures Seizure
Tetany Tetany (medical sign)
Paralysis
Abnormal heart rhythms Heart arrhythmia
QT interval
Electrocardiogram
Sudden cardiac death
Amino acid

Cause

Diagnosis

Genetic testing
Introns Intron
Proton-pump inhibitors Proton-pump inhibitor
Aminoglycosides Aminoglycoside
Primary aldosteronism
EAST syndrome
Renal cysts and diabetes syndrome
CLCNKB
Transfer RNAs Transfer RNA
MT-TI
MT-TF
Mitochondrial DNA
Homoplasmic Homoplasmy

Treatment

Epidemiology

Prevalence

History

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes68

Edges67

Triples99

Avg. degree1.97

Density0.029412

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Gitelman syndrome

Top relations

related to Differential diagnosis · 26

Gitelman syndrome → Bartter, CLCNKB, Disease-causing, Diuretic, DNA, EAST, Gitelman, Gitelman-like, In Gitelman, Lastly, Laxative, Many, Medication, MT-TF, MT-TI, Primary, Proton-pump, Renal, RNAs, Secondly

related to Diagnosis · 13

Gitelman syndrome → BMP, CMP, Diagnosis, Electrolyte, Genetic, Gitelman, Other, SLC12A3, Symptom, The, This, Urinary, When

related to Signs and symptoms · 12

Gitelman syndrome → Abnormal, Affected, Clinical, Gitelman, Gordon's, In, Individuals, More, QT, Quality, Symptomatic, Though

related to External links · 11

Gitelman syndrome → Clinician Resource, Gitelman, Gitelman Syndrome Online Resource, Gitelman Syndrome UK, Medical Professionals, Medicine, MedlinePlus, National Gitelman Association, National Library, Online Resource, Patient

has treatment · 9

Gitelman syndrome → Aldosterone, Diarrhea, Dietary, Gitelman, However, Large, Most, Severe, To

related to Cause · 8

Gitelman syndrome → Gitelman, In, It, NCC, SLC12A3, The, This, Thus

related to Epidemiology · 7

Gitelman syndrome → Estimates, Gitelman, Heterozygous, However, SLC12A3, The, This

Causes · 1

Gitelman syndrome → Mutations in SLC12A3, CLCNKB, MT-TI, MT-TF

Other names · 1

Gitelman syndrome → Primary renal tubular hypokalemic hypomagnesemia with hypocalciuria

Specialty · 1

Gitelman syndrome → Nephrology

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gitelman syndrome slc12a3 potassium magnesium gene tubule levels distal convoluted ncc low sodium chloride symptoms variants patients blood electrolyte genetic

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Gitelman syndrome	Causes	Mutations in SLC12A3, CLCNKB, MT-TI, MT-TF	1.00	infobox
Gitelman syndrome	Other names	Primary renal tubular hypokalemic hypomagnesemia with hypocalciuria	1.00	infobox
Gitelman syndrome	Specialty	Nephrology	1.00	infobox
seizures	instance of	More severe symptoms	0.80	text
tetany	instance of	More severe symptoms	0.80	text
and paralysis have been reported	instance of	More severe symptoms	0.80	text
gentamicin can cause a transient metabolic alkalosis with hypokalaemia	instance of	and aminoglycosides	0.80	text
hypomagnesaemia that resolves 2	instance of	and aminoglycosides	0.80	text
amiloride have also been suggested as possible treatments	instance of	or epithelial sodium channel blockers	0.80	text
because they decrease urinary wasting of potassium	instance of	or epithelial sodium channel blockers	0.80	text
infants	instance of	Most asymptomatic individuals with Gitelman syndrome can be monitored without medical treatment.In patients with early onset of the disease	0.80	text
children	instance of	Most asymptomatic individuals with Gitelman syndrome can be monitored without medical treatment.In patients with early onset of the disease	0.80	text

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3