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Gene polymorphism

A gene is said to be polymorphic if more than one allele occupies that gene's locus within a population. In addition to having more than one allele at a specific locus, each allele must also occur in the population at a rate of at least 1% to generally be considered polymorphic.

Differences between gene polymorphism and mutation, Clinical significance & Overview

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Differences between gene polymorphism and mutation

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Clinical significance

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Gene polymorphism

Nodes77
Edges76
Triples18
Avg. degree1.97
Density0.025974
Components1

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Important terminology

polymorphisms gene polymorphism polymorphic mutations sequence dna genes occur may protein alleles mutation allele example one variant expression also disease

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
single strand conformation polymorphism analysisinstance ofeither directly or after screening for variation with a method0.80text
HapMapinstance ofResources0.80text
DbSNPinstance ofResources0.80text
Ensemblinstance ofResources0.80text
DNA Data Bank of Japaninstance ofResources0.80text
DrugBankinstance ofResources0.80text
Kyoto Encyclopedia of Genesinstance ofResources0.80text
Genomesinstance ofResources0.80text
cigarette smokinginstance ofXPD works by cutting and removing segments of DNA that have been damaged due to things0.80text
inhalation of other environmental carcinogensinstance ofXPD works by cutting and removing segments of DNA that have been damaged due to things0.80text
mutations in various receptorsinstance ofsuch as needed to select specific molecular targets0.80text
but also understanding the polymorphisms they inherited which play important roles in diagnosisinstance ofsuch as needed to select specific molecular targets0.80text

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