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Fibrillin

Fibrillin is a glycoprotein, which is essential for the formation of elastic fibers found in connective tissue. Fibrillin is secreted into the extracellular matrix by fibroblasts and becomes incorporated into the insoluble microfibrils, which appear to provide a scaffold for deposition of elastin.

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Key facts & relationships

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Alt. symbols
FBN, MFS1, WMS
Domains
InterPro
HGNC
3603
Locus
Chr. 15 q21.1
NCBI gene
2200
OMIM
134797

Topics to explore

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Overview

Clinical aspects

Types

Advanced semantic analysis

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Map overview Semantic statistics

Fibrillin

Nodes18
Edges17
Triples32
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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Fibrillin

Top relations

related to Fibrillin-1 · 9
Fibrillin → At, Engvall, FBN1, Fibrillin-1, It, Marfan, The, This, To
related to Fibrillin-2 · 4
Fibrillin → Beals, Fibrillin-2, Mutations, Zhang
related to External links · 3
Fibrillin → Medicine Medical Subject Headings, MeSH, National Library
related to Fibrillin-3 · 2
Fibrillin → Along, More
Alt. symbols · 1
Fibrillin → FBN, MFS1, WMS
Domains · 1
Fibrillin → InterPro
HGNC · 1
Fibrillin → 3603
Locus · 1
Fibrillin → Chr. 15 q21.1
NCBI gene · 1
Fibrillin → 2200
OMIM · 1
Fibrillin → 134797

Important terminology Word statistics

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Important terminology

fibrillin-1 structure microfibrils fbn1 gene fibrillin-2 mutations 15 fibrillin-3 elastin syndrome described protein found connective tissue crystallographic chr q21 fibrillin-4

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FibrillinAlt. symbolsFBN, MFS1, WMS1.00infobox
FibrillinDomainsInterPro1.00infobox
FibrillinHGNC36031.00infobox
FibrillinLocusChr. 15 q21.11.00infobox
FibrillinNCBI gene22001.00infobox
FibrillinOMIM1347971.00infobox
FibrillinPDB2W861.00infobox
FibrillinRefSeqNM_0001381.00infobox
FibrillinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
FibrillinStructuresSwiss-model1.00infobox
FibrillinSymbolFBN11.00infobox
FibrillinUniProtP355551.00infobox
Fibrillinis aglycoprotein0.90text

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    Min side: 3
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