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F-box protein

F-box proteins, sometimes abbreviated as FBX, are proteins containing at least one F-box domain. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the 26S proteasome.

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Key facts & relationships

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AlphaFold
IPR001810 · PF00646
Available protein structures:
IPR001810 · PF00646
InterPro
IPR001810
Membranome
630
PDB
IPR001810 PF00646 (ECOD; PDBsum)
Pfam
PF00646

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Overview

Core components

Function

Advanced semantic analysis

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Map overview Semantic statistics

F-box protein

Nodes24
Edges23
Triples32
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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F-box protein

Top relations

related to Function · 11
F-box protein → ABA, ACRE189/ACIF1, F-box, F-Box FBXL5, FOA1, For, In, IRP2, RNA, Tobacco, Tomato
related to Regulation · 5
F-box protein → F-box, For, Met30, SCF, The
AlphaFold · 2
F-box protein → IPR001810, PF00646
Available protein structures: · 2
F-box protein → IPR001810, PF00646
InterPro · 1
F-box protein → IPR001810
Membranome · 1
F-box protein → 630
PDB · 1
F-box protein → IPR001810 PF00646 (ECOD; PDBsum)
Pfam · 1
F-box protein → PF00646
Pfam clan · 1
F-box protein → CL0271
PROSITE · 1
F-box protein → PS50181

Important terminology Word statistics

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Important terminology

f-box protein proteins complex scf domain mediates one regulation components ubiquitination first identified three degradation skp2 proteasome motif interactions motifs

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
F-box proteinAlphaFoldIPR0018101.00infobox
F-box proteinAlphaFoldPF006461.00infobox
F-box proteinAvailable protein structures:IPR0018101.00infobox
F-box proteinAvailable protein structures:PF006461.00infobox
F-box proteinInterProIPR0018101.00infobox
F-box proteinMembranome6301.00infobox
F-box proteinPDBIPR001810 PF00646 (ECOD; PDBsum)1.00infobox
F-box proteinPfamPF006461.00infobox
F-box proteinPfam clanCL02711.00infobox
F-box proteinPROSITEPS501811.00infobox
F-box proteinSCOP21fs2 / SCOPe / SUPFAM1.00infobox
F-box proteinSMARTSM002561.00infobox
F-box proteinSymbolF-box1.00infobox

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