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Expanded genetic code

An expanded genetic code is an artificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 common naturally-encoded proteinogenic amino acids.

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Overview

Introduction

Codon assignment

TRNA/synthetase pair

Orthogonal ribosomes

Applications

Future

Related methods

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Map overview Semantic statistics

Expanded genetic code

Nodes77
Edges76
Triples43
Avg. degree1.97
Density0.025974
Components1

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Expanded genetic code

Top relations

related to Amber codon suppression · 25
Expanded genetic code → Additionally, As, C321, CAGE, Consequently, Escherichia, George Church, Harvard, In, K-12, Later, MAGE, Methanococcus, Normanly, O-methyltyrosine, One, Prof, RF1, Schultz, STOP
has application · 14
Expanded genetic code → Also, By, Changing, DNA, Identifying, Improving, O-methyltyrosine, One, Probing, Producing, Selective, T7, The, With
is a · 1
Expanded genetic code → artificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 common naturally-encoded proteino…

Important terminology Word statistics

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Important terminology

amino acid trna genetic codons codon acids code unnatural protein natural coli orthogonal ribosomes proteins pair one base synthetase strain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Expanded genetic codeis aartificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 common naturally-encoded proteino…0.90text
Amber codon suppressioninstance ofThis should alleviate some of the loss of fitness which currently still arises from techniques0.80text
O-methyltyrosine or dansyl alanine instead of tyrosineinstance ofBy using amino acids with slightly different size0.80text
and by inserting genetically coded reporter moietiesinstance ofBy using amino acids with slightly different size0.80text
Expanded genetic codehas applicationWith0.60section
Expanded genetic codehas applicationThe0.60section
Expanded genetic codehas applicationAlso0.60section
Expanded genetic codehas applicationProbing0.60section
Expanded genetic codehas applicationBy0.60section
Expanded genetic codehas applicationO-methyltyrosine0.60section
Expanded genetic codehas applicationIdentifying0.60section
Expanded genetic codehas applicationChanging0.60section

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