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The exome is composed of all of the exons within the genome, the sequences which, when transcribed, remain within the mature RNA after introns are removed by RNA splicing. This includes untranslated regions of messenger RNA (mRNA), and coding regions. Exome sequencing has proven to be an efficient method of determining the genetic basis of more than two…
Regions, Next-generation sequencing & Diseases and diagnoses
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sequencing genome exons rna whole-exome mutations genetic disorders mendelian dna disease rare within patients coding also transcriptome transcribed regions efficient
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Exome | is a | part of the genome composed of exons | 0.90 | text |
| Sanger sequencing | instance of | and replacing older methods | 0.80 | text |
| karyotyping | instance of | It has also been found to be more effective than other methods | 0.80 | text |
| microarrays | instance of | It has also been found to be more effective than other methods | 0.80 | text |
| Exome | related to Definition | The | 0.60 | section |
| Exome | related to Definition | RNA | 0.60 | section |
| Exome | related to Definition | While | 0.60 | section |
| Exome | related to Definition | As | 0.60 | section |
| Exome | related to Definition | Different | 0.60 | section |
| Exome | related to Diseases and diagnoses | Rare | 0.60 | section |
| Exome | related to Diseases and diagnoses | Mendelian | 0.60 | section |
| Exome | related to Diseases and diagnoses | In | 0.60 | section |
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