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ETS2

ETS2 is a gene that in humans is encoding the C-ETS2 protein. The protein encoded by this gene belongs to the ETS family of transcription factors. It has been found to play a key role in the development of inflammatory bowel disease.

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Aliases
ETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4BQA, 4MHV
Band
21q22.2 · 16 C4|16 56.64 cM
Bgee
skin of abdomen · mucosa of urinary bladder · skin of leg · gastric mucosa · rectum
BioGPS
More reference expression data
Chr.
Chromosome 21 (human) · Chromosome 16 (mouse)

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Map overview Semantic statistics

ETS2

Nodes19
Edges18
Triples91
Avg. degree1.89
Density0.105263
Components1

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ETS2

Top relations

Gene ontology · 25
ETS2 → cell differentiation, cytosol, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, ectodermal cell fate commitment, glucocorticoid receptor binding, mesoderm development, negative regulation of transcription by RNA polymerase II, nucleoplasm, nucleus, plasma membrane, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, primitive streak formation, protein binding, protein domain specific binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated
Bgee · 19
ETS2 → conjunctival fornix, ectocervix, gastric mucosa, granulocyte, left lung lobe, mucosa of urinary bladder, olfactory zone of nasal mucosa, Paneth cell, rectum, right lung, right lung lobe, skin of abdomen, skin of back, skin of external ear, skin of leg, spleen, tail of embryo, thymus, upper lobe of left lung
RNA expression pattern · 19
ETS2 → conjunctival fornix, ectocervix, gastric mucosa, granulocyte, left lung lobe, mucosa of urinary bladder, olfactory zone of nasal mucosa, Paneth cell, rectum, right lung, right lung lobe, skin of abdomen, skin of back, skin of external ear, skin of leg, spleen, tail of embryo, thymus, upper lobe of left lung
related to Interactions · 3
ETS2 → C-jun, Cyclin-dependent, ERG
Band · 2
ETS2 → 16 C4|16 56.64 cM, 21q22.2
Chr. · 2
ETS2 → Chromosome 16 (mouse), Chromosome 21 (human)
End · 2
ETS2 → 38,824,955 bp, 95,522,095 bp
Aliases · 1
ETS2 → ETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor
Available structures · 1
ETS2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4BQA, 4MHV
BioGPS · 1
ETS2 → More reference expression data

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Important terminology

gene bp chr human band chromosome 21 protein transcription external location mouse ets development inflammatory bowel disease factor search 824

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ETS2AliasesETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor1.00infobox
ETS2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4BQA, 4MHV1.00infobox
ETS2Band21q22.21.00infobox
ETS2Band16 C4|16 56.64 cM1.00infobox
ETS2Bgeeskin of abdomen1.00infobox
ETS2Bgeemucosa of urinary bladder1.00infobox
ETS2Bgeeskin of leg1.00infobox
ETS2Bgeegastric mucosa1.00infobox
ETS2Bgeerectum1.00infobox
ETS2Bgeespleen1.00infobox
ETS2Bgeeupper lobe of left lung1.00infobox
ETS2Bgeeectocervix1.00infobox
ETS2Bgeeolfactory zone of nasal mucosa1.00infobox
ETS2Bgeeright lung1.00infobox
ETS2Bgeeleft lung lobe1.00infobox
ETS2Bgeetail of embryo1.00infobox
ETS2Bgeethymus1.00infobox
ETS2BgeePaneth cell1.00infobox
ETS2Bgeegranulocyte1.00infobox
ETS2Bgeeskin of external ear1.00infobox
ETS2Bgeeskin of back1.00infobox
ETS2Bgeeconjunctival fornix1.00infobox
ETS2Bgeeright lung lobe1.00infobox
ETS2BioGPSMore reference expression data1.00infobox
ETS2Chr.Chromosome 21 (human)1.00infobox
ETS2Chr.Chromosome 16 (mouse)1.00infobox
ETS2DatabasesNCBI: entry; OMA: entry1.00infobox
ETS2End38,824,955 bp1.00infobox
ETS2End95,522,095 bp1.00infobox
ETS2EnsemblENSG000001575571.00infobox

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