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Etomidate

Etomidate, sold under the brand name Amidate, is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, cardioversion and electroconvulsive therapy. It was developed at Janssen Pharmaceutica in 1964 and was introduced as an…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N01AX07 (WHO)
Boiling point
392 °C (738 °F)
CAS Number
33125-97-2 Y
ChEMBL
ChEMBL23731 Y

Topics to explore

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Overview

Medical uses

Use in executions

Adverse effects

Pharmacology

Metabolism

Formulation

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Etomidate

Nodes86
Edges85
Triples116
Avg. degree1.98
Density0.023256
Components1

How this topic connects Entity context

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Etomidate

Top relations

related to Recreational use · 14
Etomidate → Australia, By, CF2-Etomidate, CF3-Etomidate, CF3-Propoxate, China, Chinese, Dichloro-3-fluoroetomidate, Hong Kong, New Zealand, Singapore, Taiwan, Thailand, Vape
has effect · 13
Etomidate → Because, Continuous, Cortisol, For, Hohl, However, In, Jabre, Other, Rapid Sequence Induction, The, Thus, Using
Legal status · 6
Etomidate → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, Scheduled in Taiwan and Hong Kong; ℞-only in China, UK: POM (Prescription only), US: ℞-only
related to Pharmacokinetics · 6
Etomidate → At, Hepatic, L/kgProtein, Metabolism, Onset, Vd
related to Use in executions · 6
Etomidate → August, Florida, He, Mark James Asay, The US, US
related to External links · 5
Etomidate → Archived, Drug Information Portal, Medicine, National Library, October
related to Pharmacodynamics · 4
Etomidate → At, GABA, GABAA, Its
related to Speech and memory test · 4
Etomidate → Another, However, Montreal Neurological Institute, This
related to Sedation and anesthesia · 3
Etomidate → In, It, Thus
is a · 2
Etomidate → good induction agent for people who are hemodynamically unstable, modulator at GABAA receptors containing β2 and β3 subunits

Important terminology Word statistics

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Important terminology

used use drug intravenous adrenal sedation also patients induction agent drugs people mortality effects ketamine metabolism taiwan suppression dose however

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Etomidate3D model (JSmol)Interactive image1.00infobox
EtomidateAHFS/Drugs.comMonograph1.00infobox
EtomidateATC codeN01AX07 (WHO)1.00infobox
EtomidateBoiling point392 °C (738 °F)1.00infobox
EtomidateCAS Number33125-97-2 Y1.00infobox
EtomidateChEMBLChEMBL23731 Y1.00infobox
EtomidateChemSpider33418 Y1.00infobox
EtomidateCompTox Dashboard (EPA)DTXSID50230331.00infobox
EtomidateDrugBankDB00292 Y1.00infobox
EtomidateECHA InfoCard100.046.7001.00infobox
EtomidateElimination half-life75 minutes1.00infobox
EtomidateExcretionUrine (85%) and Bile duct (15%)1.00infobox
EtomidateFormulaC14H16N2O21.00infobox
EtomidateKEGGD00548 Y1.00infobox
EtomidateLegal statusAU: S4 (Prescription only)1.00infobox
EtomidateLegal statusBR: Class C1 (Other controlled substances)1.00infobox
EtomidateLegal statusCA: ℞-only1.00infobox
EtomidateLegal statusUK: POM (Prescription only)1.00infobox
EtomidateLegal statusUS: ℞-only1.00infobox
EtomidateLegal statusScheduled in Taiwan and Hong Kong; ℞-only in China1.00infobox
EtomidateLicense dataUS DailyMed: Etomidate1.00infobox
EtomidateMelting point67 °C (153 °F)1.00infobox
EtomidateMetabolismEster hydrolysis in plasma and liver1.00infobox
EtomidateMolar mass244.294 g·mol−11.00infobox
EtomidateProtein binding76%1.00infobox
EtomidatePubChem CID363391.00infobox
EtomidateRoutes of administrationIntravenous1.00infobox
EtomidateTrade namesAmidate, Hypnomidate, Tomvi1.00infobox
EtomidateUNIIZ22628B5981.00infobox
Etomidateis agood induction agent for people who are hemodynamically unstable0.90text

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