Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

ERCC5

DNA repair protein complementing XP-G cells is a protein that in humans is encoded by the ERCC5 gene.

Applications & Products

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around ERCC5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ERCC5, COFS3, ERCM2, UVDR, XPG, XPGC, ERCC5-201, excision repair cross-complementation group 5, ERCC excision repair 5, endonuclease
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EKF, 5EKG
Band
13q33.1 · 1 C1.1|1 23.55 cM
Bgee
granulocyte · Achilles tendon · body of pancreas · skin of leg · skin of abdomen
BioGPS
More reference expression data
Chr.
Chromosome 13 (human) · Chromosome 1 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Syndromes

Mouse model

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

ERCC5

Nodes22
Edges21
Triples115
Avg. degree1.91
Density0.090909
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

ERCC5

Top relations

Gene ontology · 35
ERCC5 → bubble DNA binding, catalytic activity, cellular response to DNA damage stimulus, DNA binding, DNA repair, DNA replication factor A complex, double-stranded DNA binding, endodeoxyribonuclease activity, endonuclease activity, hydrolase activity, hydrolase activity, acting on ester bonds, metal ion binding, negative regulation of apoptotic process, nuclease activity, nucleoplasm, nucleotide-excision repair, nucleotide-excision repair complex, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion
Bgee · 20
ERCC5 → Achilles tendon, anterior pituitary, body of pancreas, ciliary body, corneal stroma, ganglionic eminence, genital tubercle, granulocyte, mucosa of transverse colon, neural layer of retina, right lobe of liver, right lung, Rostral migratory stream, skin of abdomen, skin of leg, stroma of bone marrow, supraoptic nucleus, tail of embryo, tibial nerve, ventricular zone
RNA expression pattern · 20
ERCC5 → Achilles tendon, anterior pituitary, body of pancreas, ciliary body, corneal stroma, ganglionic eminence, genital tubercle, granulocyte, mucosa of transverse colon, neural layer of retina, right lobe of liver, right lung, Rostral migratory stream, skin of abdomen, skin of leg, stroma of bone marrow, supraoptic nucleus, tail of embryo, tibial nerve, ventricular zone
related to Function · 5
ERCC5 → Cockayne, Excision, Multiple, Mutations, UV-induced DNA
related to Mouse model · 5
ERCC5 → An Ercc5, Dietary, DNA, These, Xpg
related to Syndromes · 5
ERCC5 → Cockayne, CS, Mutational, XP, Xpg
Band · 2
ERCC5 → 1 C1.1|1 23.55 cM, 13q33.1
Chr. · 2
ERCC5 → Chromosome 1 (mouse), Chromosome 13 (human)
End · 2
ERCC5 → 102,875,995 bp, 44,220,420 bp
Aliases · 1
ERCC5 → ERCC5, COFS3, ERCM2, UVDR, XPG, XPGC, ERCC5-201, excision repair cross-complementation group 5, ERCC excision repair 5, endonuclease

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna bp gene chr human band repair mouse chromosome 13 xpg damage aging location endonuclease mutant protein excision function external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ERCC5AliasesERCC5, COFS3, ERCM2, UVDR, XPG, XPGC, ERCC5-201, excision repair cross-complementation group 5, ERCC excision repair 5, endonuclease1.00infobox
ERCC5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5EKF, 5EKG1.00infobox
ERCC5Band13q33.11.00infobox
ERCC5Band1 C1.1|1 23.55 cM1.00infobox
ERCC5Bgeegranulocyte1.00infobox
ERCC5BgeeAchilles tendon1.00infobox
ERCC5Bgeebody of pancreas1.00infobox
ERCC5Bgeeskin of leg1.00infobox
ERCC5Bgeeskin of abdomen1.00infobox
ERCC5Bgeeright lobe of liver1.00infobox
ERCC5Bgeeanterior pituitary1.00infobox
ERCC5Bgeeright lung1.00infobox
ERCC5Bgeemucosa of transverse colon1.00infobox
ERCC5Bgeetibial nerve1.00infobox
ERCC5BgeeRostral migratory stream1.00infobox
ERCC5Bgeegenital tubercle1.00infobox
ERCC5Bgeetail of embryo1.00infobox
ERCC5Bgeestroma of bone marrow1.00infobox
ERCC5Bgeeganglionic eminence1.00infobox
ERCC5Bgeeventricular zone1.00infobox
ERCC5Bgeeneural layer of retina1.00infobox
ERCC5Bgeecorneal stroma1.00infobox
ERCC5Bgeeciliary body1.00infobox
ERCC5Bgeesupraoptic nucleus1.00infobox
ERCC5BioGPSMore reference expression data1.00infobox
ERCC5Chr.Chromosome 13 (human)1.00infobox
ERCC5Chr.Chromosome 1 (mouse)1.00infobox
ERCC5DatabasesNCBI: entry; OMA: entry1.00infobox
ERCC5End102,875,995 bp1.00infobox
ERCC5End44,220,420 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.