Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

EME1

Crossover junction endonuclease EME1 is an enzyme that is encoded by the EME1 gene in humans. It forms a complex with MUS81 which resolves Holliday junctions. In mammalian cells the EME1/MUS81 protein complex is redundant for DNA damage repair with GEN1 endonuclease. In mice, EME1/MUS81 and GEN1 redundantly contribute to Holliday junction processing.…

Overview, Related Topics & Entities

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around EME1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EME1, MMS4L, SLX2A, essential meiotic structure-specific endonuclease 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZIU, 2ZIV, 2ZIW, 2ZIX, 4P0P, 4P0Q, 4P0R, 4P0S
Band
17q21.33 · 11|11 D
Bgee
tail of epididymis · corpus epididymis · tendon of biceps brachii · mucosa of ileum · pancreatic ductal cell
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

EME1

Nodes14
Edges13
Triples86
Avg. degree1.86
Density0.142857
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

EME1

Top relations

Gene ontology · 22
EME1 → cellular response to DNA damage stimulus, crossover junction endodeoxyribonuclease activity, DNA binding, DNA recombination, DNA repair, double-strand break repair, endodeoxyribonuclease activity, endonuclease activity, Holliday junction resolvase complex, hydrolase activity, interstrand cross-link repair, metal ion binding, mitotic intra-S DNA damage checkpoint signaling, nuclease activity, nucleic acid phosphodiester bond hydrolysis, nucleolus, nucleoplasm, nucleus, protein binding, replication fork processing
Bgee · 20
EME1 → corpus epididymis, endothelial cell, epiblast, genital tubercle, lateral part of occipital bone, left testis, mandibular prominence, maxillary prominence, mucosa of ileum, oocyte, pancreatic ductal cell, right testis, secondary oocyte, somite, sphenoid bone, tail of embryo, tail of epididymis, tendon of biceps brachii, thyroid cartilage, yolk sac
RNA expression pattern · 20
EME1 → corpus epididymis, endothelial cell, epiblast, genital tubercle, lateral part of occipital bone, left testis, mandibular prominence, maxillary prominence, mucosa of ileum, oocyte, pancreatic ductal cell, right testis, secondary oocyte, somite, sphenoid bone, tail of embryo, tail of epididymis, tendon of biceps brachii, thyroid cartilage, yolk sac
Band · 2
EME1 → 11|11 D, 17q21.33
Chr. · 2
EME1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
EME1 → 50,381,483 bp, 94,544,790 bp
Aliases · 1
EME1 → EME1, MMS4L, SLX2A, essential meiotic structure-specific endonuclease 1
Available structures · 1
EME1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZIU, 2ZIV, 2ZIW, 2ZIX, 4P0P, 4P0Q, 4P0R, 4P0S
BioGPS · 1
EME1 → More reference expression data
Databases · 1
EME1 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gen1 dna bp mice chr repair human band endonuclease mus81 gene chromosome 17 redundant junction complex holliday meiotic homozygous mutations

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
EME1AliasesEME1, MMS4L, SLX2A, essential meiotic structure-specific endonuclease 11.00infobox
EME1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2ZIU, 2ZIV, 2ZIW, 2ZIX, 4P0P, 4P0Q, 4P0R, 4P0S1.00infobox
EME1Band17q21.331.00infobox
EME1Band11|11 D1.00infobox
EME1Bgeetail of epididymis1.00infobox
EME1Bgeecorpus epididymis1.00infobox
EME1Bgeetendon of biceps brachii1.00infobox
EME1Bgeemucosa of ileum1.00infobox
EME1Bgeepancreatic ductal cell1.00infobox
EME1Bgeeoocyte1.00infobox
EME1Bgeeendothelial cell1.00infobox
EME1Bgeeright testis1.00infobox
EME1Bgeeleft testis1.00infobox
EME1Bgeesecondary oocyte1.00infobox
EME1Bgeelateral part of occipital bone1.00infobox
EME1Bgeegenital tubercle1.00infobox
EME1Bgeetail of embryo1.00infobox
EME1Bgeeepiblast1.00infobox
EME1Bgeesomite1.00infobox
EME1Bgeeyolk sac1.00infobox
EME1Bgeethyroid cartilage1.00infobox
EME1Bgeemaxillary prominence1.00infobox
EME1Bgeemandibular prominence1.00infobox
EME1Bgeesphenoid bone1.00infobox
EME1BioGPSMore reference expression data1.00infobox
EME1Chr.Chromosome 17 (human)1.00infobox
EME1Chr.Chromosome 11 (mouse)1.00infobox
EME1DatabasesNCBI: entry; OMA: entry1.00infobox
EME1End50,381,483 bp1.00infobox
EME1End94,544,790 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.