Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
DNA ligase 1 also DNA ligase I, is an enzyme that in humans is encoded by the LIG1 gene. DNA ligase 1 is the only known eukaryotic DNA ligase involved in both DNA replication and repair, making it the most studied of the ligases.
The analysis highlights Recruitment and regulation, Function and mechanism and Role in damaged base repair as prominent areas in the source structure around DNA ligase 1.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around DNA ligase 1 shows recurring relationship patterns in the source. For example, DNA ligase 1 → Activation, Although, Both, C-terminal, C-terminus, CDK, CKII, Cy, DBD, DNA, II, LIG1, Moreover, N-terminal, N-terminal DNA, N-terminus, NLS, NTase, OB, PCNA Another extracted example is DNA ligase 1 → anatomical structure morphogenesis, ATP binding, base-excision repair, cell cycle, cell division, cellular response to DNA damage stimulus, cytoplasm, DNA binding, DNA biosynthetic process, DNA ligase (ATP) activity, DNA ligase activity, DNA ligation, DNA ligation involved in DNA repair, DNA mismatch repair, DNA recombination, DNA repair, DNA replication, intracellular membrane-bounded organelle, lagging strand elongation, ligase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
dna ligase repair replication bp lig1 human cell chr band known enzyme gene n-terminal nick chromosome 19 strand immunodeficiency catalytic
TTTA extracted 176 structured relationships around DNA ligase 1. Examples in this analysis include DNA ligase 1 → 6.5.1.1 → ↗ and DNA ligase 1 → Aliases → LIG1, DNA ligase 1, LIGI, hLig1, IMD96. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DNA ligase 1 | 6.5.1.1 | ↗ | 1.00 | infobox |
| DNA ligase 1 | Aliases | LIG1, DNA ligase 1, LIGI, hLig1, IMD96 | 1.00 | infobox |
| DNA ligase 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1X9N | 1.00 | infobox |
| DNA ligase 1 | Band | 19q13.33 | 1.00 | infobox |
| DNA ligase 1 | Band | 7 A1|7 7.82 cM | 1.00 | infobox |
| DNA ligase 1 | Bgee | right uterine tube | 1.00 | infobox |
| DNA ligase 1 | Bgee | ventricular zone | 1.00 | infobox |
| DNA ligase 1 | Bgee | ganglionic eminence | 1.00 | infobox |
| DNA ligase 1 | Bgee | sural nerve | 1.00 | infobox |
| DNA ligase 1 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| DNA ligase 1 | Bgee | left testis | 1.00 | infobox |
| DNA ligase 1 | Bgee | granulocyte | 1.00 | infobox |
| DNA ligase 1 | Bgee | gonad | 1.00 | infobox |
| DNA ligase 1 | Bgee | right testis | 1.00 | infobox |
| DNA ligase 1 | Bgee | testicle | 1.00 | infobox |
| DNA ligase 1 | Bgee | tail of embryo | 1.00 | infobox |
| DNA ligase 1 | Bgee | genital tubercle | 1.00 | infobox |
| DNA ligase 1 | Bgee | outer renal medulla | 1.00 | infobox |
| DNA ligase 1 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| DNA ligase 1 | Bgee | inner renal medulla | 1.00 | infobox |
| DNA ligase 1 | Bgee | primitive streak | 1.00 | infobox |
| DNA ligase 1 | Bgee | epiblast | 1.00 | infobox |
| DNA ligase 1 | Bgee | somite | 1.00 | infobox |
| DNA ligase 1 | Bgee | yolk sac | 1.00 | infobox |
| DNA ligase 1 | Bgee | maxillary prominence | 1.00 | infobox |
| DNA ligase 1 | BioGPS | More reference expression data | 1.00 | infobox |
| DNA ligase 1 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| DNA ligase 1 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| DNA ligase 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| DNA ligase 1 | End | 48,170,603 bp | 1.00 | infobox |
The concept neighborhoods around DNA ligase 1 bring nearby vocabulary together. In this analysis, examples include Ligase, Repair and Replication. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For DNA ligase 1, one of the stronger structural bridges in this analysis connects DNA ligase 1 with Recruitment and regulation. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around DNA ligase 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Recruitment and regulation, Function and mechanism & Role in damaged base repair, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — DNA ligase 1 · EN edition · Analysis: TopicsToTalkAbout