DNA gyrase

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DNA gyrase topic overview

The analysis highlights Standards, Overview and Inhibition by antibiotics as prominent areas in the source structure around DNA gyrase.

Related topics: 39
Source areas: 5
Connected nodes: 44
Extracted relationships: 64
Concept neighborhoods: 20
Bridge connections: 44

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 21 topics

Inhibition by antibiotics · 6 topics

Phage T4 · 6 topics

Gyrase specificity · 4 topics

Mechanochemical model of gyrase activity · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA: enzyme data
EC no.: 5.6.2.2
ExPASy: NiceZyme view
KEGG: enzyme entry
MetaCyc: metabolic pathway
NCBI: proteins

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Enzyme
Topoisomerase
Type II topoisomerases Type II topoisomerase
DNA
RNA-polymerase RNA polymerase
Helicase
DNA replication
Supercoiling DNA supercoil
Linking number
Bacterial Bacteria
Plastids Plastid
Apicoplast
Plasmodium falciparum
Antibiotics Antibiotic
Nalidixic acid
Novobiocin
Albicidin
Ciprofloxacin
Transcription Transcription (genetics)
DNA polymerase
Topoisomerase IV

Mechanochemical model of gyrase activity

ATP Adenosine triphosphate
Double-strand break DNA repair

Gyrase specificity

Inhibition by antibiotics

Antibiotics
Aminocoumarins Aminocoumarin
Coumermycin A1
Competitive inhibition
Quinolones Quinolone antibiotic
Double-strand breaks Double-strand break

Phage T4

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DNA gyrase connects Entity context

The extracted context around DNA gyrase shows recurring relationship patterns in the source. For example, DNA gyrase → AT-rich, C-terminal, DNA, Escherichia, GC-rich, GyrA, Gyrase, It, Mu, Recently, SGS, SGSs, Strong, The, Topo-Seq Another extracted example is DNA gyrase → ATP, ATPase, Binding, C-gates, DNA, DNA-gates, GyrA, GyrB, Hydrolysis, N-gates, Structurally. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Gyrase specificity · 15

DNA gyrase → AT-rich, C-terminal, DNA, Escherichia, GC-rich, GyrA, Gyrase, It, Mu, Recently, SGS, SGSs, Strong, The, Topo-Seq

related to Gyrase structure · 11

DNA gyrase → ATP, ATPase, Binding, C-gates, DNA, DNA-gates, GyrA, GyrB, Hydrolysis, N-gates, Structurally

related to Inhibition by antibiotics · 11

DNA gyrase → ATPase, By, Coumermycin A1, DNA, G-segment, Gyrase, GyrB, Quinolone-resistant, The, This, Two

related to External links · 6

DNA gyrase → APDBe-KB P0A2I3, DNA, Escherichia, PDB, PDBe-KB P0AES4, Salmonella

related to Phage T4 · 5

DNA gyrase → DNA, Mutants, Phage T4, Since, The

BRENDA · 1

DNA gyrase → enzyme data

EC no. · 1

DNA gyrase → 5.6.2.2

ExPASy · 1

DNA gyrase → NiceZyme view

KEGG · 1

DNA gyrase → enzyme entry

MetaCyc · 1

DNA gyrase → metabolic pathway

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna gyrase atp supercoils enzyme replication antibiotics binding two positive phage also bacterial subunits molecules subunit negative ability topoisomerase gyra

DNA gyrase relationships Subject–Predicate–Object triples

TTTA extracted 64 structured relationships around DNA gyrase. Examples in this analysis include DNA gyrase → BRENDA → enzyme data and DNA gyrase → EC no. → 5.6.2.2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
DNA gyrase	BRENDA	enzyme data	1.00	infobox
DNA gyrase	EC no.	5.6.2.2	1.00	infobox
DNA gyrase	ExPASy	NiceZyme view	1.00	infobox
DNA gyrase	KEGG	enzyme entry	1.00	infobox
DNA gyrase	MetaCyc	metabolic pathway	1.00	infobox
DNA gyrase	NCBI	proteins	1.00	infobox
DNA gyrase	PDB structures	RCSB PDB PDBe PDBsum	1.00	infobox
DNA gyrase	PMC	articles	1.00	infobox
DNA gyrase	PubMed	articles	1.00	infobox
DNA gyrase	Rhea	reactions	1.00	infobox
DNA gyrase	Search	SearchPMCarticlesPubMedarticlesNCBIproteins	1.00	infobox
DNA gyrase	is a	target of many antibiotics	0.90	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around DNA gyrase bring nearby vocabulary together. In this analysis, examples include Gyrase, Supercoils and Enzyme. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

DNA gyrase
- Gyrase
- Supercoils
- Enzyme
- Replication
- Atp
- Two
- Binding
- Antibiotics
- Coli
- Motif
- Negative
- Phage
dna gyrase
- Gyrase
- Supercoils
- Enzyme
- Replication
- Atp
- Two
- Bacterial
- Coli
- Binding
- Antibiotics
- Phage
- Motif
dna
- Gyrase
- Supercoils
- Enzyme
- Replication
- Atp
- Two
- Binding
- Coli
- Motif
- Negative
- Phage
- Subunits
dna replication
- Gyrase
- Positive
- Phage
- Ahead
- Polymerase
- Relax
- Supercoils
- Ability
- Genes
- Topoisomerase
- Enzyme
- Replication
dna polymerase
- Positive
- Gyrase
- Relax
- Replication
- Supercoils
- Tension
- Topoisomerase
- Enzyme
- Atp
- Two
- Binding
- Coli
mechanochemical model of gyrase activity
- Replication
- Bacterial
- Coli
- Antibiotics
- Phage
- Supercoils
- Ability
- Motif
- Gyra
- Gyrb
- Molecules
- Subunit
gyrase specificity
- Replication
- Bacterial
- Coli
- Antibiotics
- Phage
- Supercoils
- Ability
- Motif
- Gyra
- Gyrb
- Molecules
- Subunit
atp
- Molecules
- Cycle
- Hydrolysis
- Dna
- Gyrase
- Catalytic
- Negative
- Two
- Supercoils
- Binding
- Allows
- Ability

Connections between topic areas Semantic bridges

For DNA gyrase, one of the stronger structural bridges in this analysis connects DNA gyrase with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

DNA gyrase — Overview · splits 23 ⟂ 22

DNA gyrase — Inhibition by antibiotics · splits 38 ⟂ 7

DNA gyrase — Phage T4 · splits 38 ⟂ 7

DNA gyrase — Gyrase specificity · splits 40 ⟂ 5

DNA gyrase — Mechanochemical model of gyrase activity · splits 42 ⟂ 3

Map overview Semantic statistics

DNA gyrase

Nodes45

Edges44

Triples64

Avg. degree1.96

Density0.044444

Components1

Source & methodology

TTTA analyzes the structure around DNA gyrase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Overview & Inhibition by antibiotics, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DNA gyrase · EN edition · Analysis: TopicsToTalkAbout