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Direct coupling analysis

Direct coupling analysis or DCA is an umbrella term comprising several methods for analyzing sequence data in computational biology. The common idea of these methods is to use statistical modeling to quantify the strength of the direct relationship between two positions of a biological sequence, excluding effects from other positions. This contrasts…

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Direct coupling analysis

Nodes52
Edges51
Triples0
Avg. degree1.96
Density0.038462
Components1

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positions displaystyle model protein sequence direct dca residue interaction used two example parameters symbols large contacts structure couplings sequences msa

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