Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Defactinib (INN, codenamed VS-6063) is an inhibitor of PTK2, also known as focal adhesion kinase (FAK), Pyk2, and MELK which was developed by Pfizer and licensed to Verastem Oncology as a potential treatment for solid tumors.
Overview, Related Topics & Entities
Explore the main themes, entities and connections around Defactinib. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the full topic structure. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
See the strongest relationship patterns around the current topic before diving into the raw triples.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
also vs-6063 inn inhibitor pyk2 melk pfizer mesothelioma nf2 codenamed ptk2 known focal adhesion kinase fak developed licensed verastem oncology
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Defactinib | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Defactinib | CAS Number | 1073154-85-4 | 1.00 | infobox |
| Defactinib | ChEMBL | ChEMBL3137331 | 1.00 | infobox |
| Defactinib | ChemSpider | 32695161 | 1.00 | infobox |
| Defactinib | CompTox Dashboard (EPA) | DTXSID901025937 | 1.00 | infobox |
| Defactinib | DrugBank | DB12282 | 1.00 | infobox |
| Defactinib | Formula | C20H21F3N8O3S | 1.00 | infobox |
| Defactinib | KEGG | D10618 | 1.00 | infobox |
| Defactinib | Molar mass | 510.50 g·mol−1 | 1.00 | infobox |
| Defactinib | Other names | PF-04554878, VS-6063 | 1.00 | infobox |
| Defactinib | PDB ligand | 7KD (PDBe, RCSB PDB) | 1.00 | infobox |
| Defactinib | PubChem CID | 25117126 | 1.00 | infobox |
| Defactinib | UNII | 53O87HA2QU | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.