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Dactinomycin

Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. It is given by injection into a vein.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L01DA01 (WHO)
CAS Number
50-76-0 Y
ChEBI
CHEBI:27666 Y
ChEMBL
ChEMBL1554 Y

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Overview

Medical use

Side effects

Mechanism

History

Research use

Biosynthesis

Advanced semantic analysis

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Map overview Semantic statistics

Dactinomycin

Nodes73
Edges72
Triples50
Avg. degree1.97
Density0.027397
Components1

How this topic connects Entity context

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Dactinomycin

Top relations

related to External links · 5
Dactinomycin → Archived, Drug Information Portal, July, Medicine, National Library
Legal status · 4
Dactinomycin → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
Other names · 4
Dactinomycin → Actinomycin C1, Actinomycin D, Actinomycin IV, Meractinomycin
3D model (JSmol) · 1
Dactinomycin → Interactive image
AHFS/Drugs.com · 1
Dactinomycin → Monograph
ATC code · 1
Dactinomycin → L01DA01 (WHO)
CAS Number · 1
Dactinomycin → 50-76-0 Y
ChEBI · 1
Dactinomycin → CHEBI:27666 Y
ChEMBL · 1
Dactinomycin → ChEMBL1554 Y
ChemSpider · 1
Dactinomycin → 10482167 Y

Important terminology Word statistics

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Important terminology

actinomycin side effects use dna used cancer two 4-mha also tumor occurs types include tryptophan pregnancy medical rhabdomyosarcoma extravasation antibiotic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dactinomycin3D model (JSmol)Interactive image1.00infobox
DactinomycinAHFS/Drugs.comMonograph1.00infobox
DactinomycinATC codeL01DA01 (WHO)1.00infobox
DactinomycinCAS Number50-76-0 Y1.00infobox
DactinomycinChEBICHEBI:27666 Y1.00infobox
DactinomycinChEMBLChEMBL1554 Y1.00infobox
DactinomycinChemSpider10482167 Y1.00infobox
DactinomycinCompTox Dashboard (EPA)DTXSID90200311.00infobox
DactinomycinDrugBankDB00970 N1.00infobox
DactinomycinECHA InfoCard100.000.0581.00infobox
DactinomycinElimination half-life36 hours1.00infobox
DactinomycinExcretionBile1.00infobox
DactinomycinFormulaC62H86N12O161.00infobox
DactinomycinKEGGC06770 N1.00infobox
DactinomycinLegal statusAU: S4 (Prescription only)1.00infobox
DactinomycinLegal statusCA: ℞-only1.00infobox
DactinomycinLegal statusUK: POM (Prescription only)1.00infobox
DactinomycinLegal statusUS: ℞-only1.00infobox
DactinomycinMedlinePlusa6822241.00infobox
DactinomycinMetabolismhepatic1.00infobox
DactinomycinMolar mass1255.438 g·mol−11.00infobox
DactinomycinNIAID ChemDB0098851.00infobox
DactinomycinOther namesActinomycin C11.00infobox
DactinomycinOther namesActinomycin D1.00infobox
DactinomycinOther namesActinomycin IV1.00infobox
DactinomycinOther namesMeractinomycin1.00infobox
DactinomycinPregnancy categoryAU: D1.00infobox
DactinomycinProtein binding5%1.00infobox
DactinomycinPubChem CID4571931.00infobox
DactinomycinRoutes of administrationIV1.00infobox

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