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Cytotoxicity refers to the capacity of a substance or agent to damage or kill living cells, reflecting a critical parameter in pharmacology, toxicology, and biomedicine. It is distinct from cytostatic effects, which inhibit cell growth and proliferation without causing cell death. Cytotoxic agents can induce a range of cellular responses, including…
Measurement, Types & Clinical significance
Explore the main themes, entities and connections around Cytotoxicity. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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cell cells membrane cytotoxic integrity effects necrosis assays death methods apoptotic cellular compounds also activity assay distinct including growth proliferation
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| trypan blue or propidium iodide | instance of | Healthy cells exclude vital dyes | 0.80 | text |
| whereas damaged membranes allow these dyes to enter | instance of | Healthy cells exclude vital dyes | 0.80 | text |
| stain intracellular components | instance of | Healthy cells exclude vital dyes | 0.80 | text |
| Cytotoxicity | has method | Additional | 0.60 | section |
| Cytotoxicity | has method | SRB | 0.60 | section |
| Cytotoxicity | has method | WST | 0.60 | section |
| Cytotoxicity | has method | To | 0.60 | section |
| Cytotoxicity | has method | For | 0.60 | section |
| Cytotoxicity | has method | LDH-XTT-NR | 0.60 | section |
| Cytotoxicity | has method | Label-free | 0.60 | section |
| Cytotoxicity | has method | Electric | 0.60 | section |
| Cytotoxicity | has method | ECIS | 0.60 | section |
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