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Cycloserine: History, Applications & Research

Cycloserine, sold under the brand name Seromycin, is a broad-spectrum antibiotic used as a second-line treatment for advanced tuberculosis and, rarely, urinary tract infections (UTIs). Specifically, it is used in conjunction with other antituberculosis medications for the treatment of active drug resistant tuberculosis. Cycloserine's use for the…

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Cycloserine topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Cycloserine.

Related topics
82
Source areas
6
Connected nodes
88
Extracted relationships
75
Concept neighborhoods
22
Bridge connections
88

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 35 topics
Research · 16 topics
Medical uses · 14 topics
Pharmacology · 12 topics
Chemistry · 3 topics
History · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J04AB01 (WHO)
Bioavailability
~70% to 90%
CAS Number
68-41-7 Y
ChEBI
CHEBI:40009 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Pharmacology

Chemistry

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cycloserine connects Entity context

The extracted context around Cycloserine shows recurring relationship patterns in the source. For example, Cycloserine → August, Chao Center, Contract Manufacturing, Due, Eli Lilly, In, Industrial Pharmacy, NGO, Purdue University, Purdue University Research Foundation, Rodelis, Rodelis Therapeutics, The, US Another extracted example is Cycloserine → Alr, As, ATP-dependent D-alanine-D-alanine, D-alanine, Ddl, If, L-alanine, NMDA, Psychiatric, The, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cycloserine

Top relations

related to Economics · 14
Cycloserine → August, Chao Center, Contract Manufacturing, Due, Eli Lilly, In, Industrial Pharmacy, NGO, Purdue University, Purdue University Research Foundation, Rodelis, Rodelis Therapeutics, The, US
related to Mechanism of action · 11
Cycloserine → Alr, As, ATP-dependent D-alanine-D-alanine, D-alanine, Ddl, If, L-alanine, NMDA, Psychiatric, The, This
related to Urinary tract infections · 8
Cycloserine → Acinetobacter, Additionally, Consequently, Cycloserine's, Enterobacter, Klebsiella, Pseudomonas, UTIs
related to Psychiatric disorders · 6
Cycloserine → Adding D-cycloserine, Another, Cochrane, Evidence, OCD, Reviews
has effect · 3
Cycloserine → Amanita, GABAA, It
related to Tuberculosis · 3
Cycloserine → Because, MDR-TB, XDR-TB
related to Chemical properties · 2
Cycloserine → D-serine, Under
3D model (JSmol) · 1
Cycloserine → Interactive image
AHFS/Drugs.com · 1
Cycloserine → Monograph
ATC code · 1
Cycloserine → J04AB01 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

treatment effects tuberculosis used synthesis drug use d-alanine compound utis side depression may research antibiotic found urinary streptomyces psychiatric form

Cycloserine relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around Cycloserine. Examples in this analysis include Cycloserine → 3D model (JSmol) → Interactive image and Cycloserine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cycloserine3D model (JSmol)Interactive image1.00infobox
CycloserineAHFS/Drugs.comMonograph1.00infobox
CycloserineATC codeJ04AB01 (WHO)1.00infobox
CycloserineBioavailability~70% to 90%1.00infobox
CycloserineCAS Number68-41-7 Y1.00infobox
CycloserineChEBICHEBI:40009 Y1.00infobox
CycloserineChEMBLChEMBL771 Y1.00infobox
CycloserineChemSpider5998 Y1.00infobox
CycloserineCompTox Dashboard (EPA)DTXSID80228701.00infobox
CycloserineDrug classAntibiotic; Alanine racemase inhibitor; D-Alanine–D-alanine ligase inhibitor; NMDA receptor partial agonist; GABA-T inhibitor1.00infobox
CycloserineDrugBankDB00260 Y1.00infobox
CycloserineECHA InfoCard100.000.6261.00infobox
CycloserineElimination half-life10 hours (normal kidney function)1.00infobox
CycloserineExcretionKidney1.00infobox
CycloserineFormulaC3H6N2O21.00infobox
CycloserineKEGGD00877 Y1.00infobox
CycloserineLegal statusUS: ℞-only1.00infobox
CycloserineLicense dataUS DailyMed: Seromycin1.00infobox
CycloserineMelting point155 to 156 °C (311 to 313 °F) (dec.)1.00infobox
CycloserineMetabolismLiver1.00infobox
CycloserineMolar mass102.093 g·mol−11.00infobox
CycloserineNIAID ChemDB0076541.00infobox
CycloserineOther names.mw-parser-output span.smallcaps{font-variant:small-caps}.mw-parser-output span.smallcaps-smaller{font-size:85%}d-cycloserine, 4-amino-3-isoxazolidinone1.00infobox
CycloserinePubChem CID62341.00infobox
CycloserineRoutes of administrationOral1.00infobox
CycloserineTrade namesSeromycin1.00infobox
CycloserineUNII95IK5KI84Z1.00infobox
Cycloserineis astructural analogue of the amino acid D-alanine and works by inhibiting bacterial cell wall synthesis0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cycloserine bring nearby vocabulary together. In this analysis, examples include Treatment, Depression and Tuberculosis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cycloserine
    • Treatment
    • Depression
    • Tuberculosis
    • Used
    • Effects
    • Antibiotic
    • Urinary
    • Research
    • Found
    • Utis
    • D-alanine
    • Use
  • cycloserine
    • Treatment
    • Depression
    • Tuberculosis
    • Used
    • Effects
    • Antibiotic
    • Urinary
    • Research
    • Found
    • Utis
    • D-alanine
    • Use
  • second-line treatment
    • Tuberculosis
    • Utis
    • Urinary
    • Used
    • Research
    • Drug
    • Tract
    • Acute
    • Depression
    • Use
    • Effects
    • Kidney
  • drug resistant tuberculosis
    • Used
    • Tract
    • Urinary
    • Utis
    • Treatment
    • Research
    • Drug
    • Tuberculosis
    • Kidney
    • Merck
    • Recommended
    • Acute
  • cycloserine/lurasidone
    • Treatment
    • Depression
    • Tuberculosis
    • Used
    • Effects
    • Antibiotic
    • Urinary
    • Research
    • Found
    • Utis
    • D-alanine
    • Use
  • broad-spectrum antibiotic
    • Infections
    • Name
    • Seromycin
    • Tract
    • Urinary
    • Tuberculosis
    • Kidney
    • Used
    • Chemical
    • Due
    • Psychiatric
    • Receptor
  • tuberculosis
    • Used
    • Tract
    • Urinary
    • Utis
    • Drug
    • Kidney
    • Merck
    • Recommended
    • Acute
    • Chemical
    • Due
    • Eli
  • antibiotic
    • Infections
    • Name
    • Seromycin
    • Tract
    • Urinary
    • Tuberculosis
    • Kidney
    • Used
    • Chemical
    • Due
    • Psychiatric
    • Receptor

Connections between topic areas Semantic bridges

For Cycloserine, one of the stronger structural bridges in this analysis connects Cycloserine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cycloserine — Overview · splits 53 ⟂ 36
Cycloserine — Research · splits 72 ⟂ 17
Cycloserine — Medical uses · splits 74 ⟂ 15
Cycloserine — Pharmacology · splits 76 ⟂ 13
Cycloserine — Chemistry · splits 85 ⟂ 4
Cycloserine — History · splits 86 ⟂ 3

Map overview Semantic statistics

Cycloserine

Nodes89
Edges88
Triples75
Avg. degree1.98
Density0.022472
Components1

Source & methodology

TTTA analyzes the structure around Cycloserine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cycloserine · EN edition · Analysis: TopicsToTalkAbout

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