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Cycloserine

Cycloserine, sold under the brand name Seromycin, is a broad-spectrum antibiotic used as a second-line treatment for advanced tuberculosis and, rarely, urinary tract infections (UTIs). Specifically, it is used in conjunction with other antituberculosis medications for the treatment of active drug resistant tuberculosis. Cycloserine's use for the…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J04AB01 (WHO)
Bioavailability
~70% to 90%
CAS Number
68-41-7 Y
ChEBI
CHEBI:40009 Y

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Medical uses

Pharmacology

Chemistry

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Map overview Semantic statistics

Cycloserine

Nodes89
Edges88
Triples75
Avg. degree1.98
Density0.022472
Components1

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Cycloserine

Top relations

related to Economics · 14
Cycloserine → August, Chao Center, Contract Manufacturing, Due, Eli Lilly, In, Industrial Pharmacy, NGO, Purdue University, Purdue University Research Foundation, Rodelis, Rodelis Therapeutics, The, US
related to Mechanism of action · 11
Cycloserine → Alr, As, ATP-dependent D-alanine-D-alanine, D-alanine, Ddl, If, L-alanine, NMDA, Psychiatric, The, This
related to Urinary tract infections · 8
Cycloserine → Acinetobacter, Additionally, Consequently, Cycloserine's, Enterobacter, Klebsiella, Pseudomonas, UTIs
related to Psychiatric disorders · 6
Cycloserine → Adding D-cycloserine, Another, Cochrane, Evidence, OCD, Reviews
has effect · 3
Cycloserine → Amanita, GABAA, It
related to Tuberculosis · 3
Cycloserine → Because, MDR-TB, XDR-TB
related to Chemical properties · 2
Cycloserine → D-serine, Under
3D model (JSmol) · 1
Cycloserine → Interactive image
AHFS/Drugs.com · 1
Cycloserine → Monograph
ATC code · 1
Cycloserine → J04AB01 (WHO)

Important terminology Word statistics

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Important terminology

treatment effects tuberculosis used synthesis drug use d-alanine compound utis side depression may research antibiotic found urinary streptomyces psychiatric form

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cycloserine3D model (JSmol)Interactive image1.00infobox
CycloserineAHFS/Drugs.comMonograph1.00infobox
CycloserineATC codeJ04AB01 (WHO)1.00infobox
CycloserineBioavailability~70% to 90%1.00infobox
CycloserineCAS Number68-41-7 Y1.00infobox
CycloserineChEBICHEBI:40009 Y1.00infobox
CycloserineChEMBLChEMBL771 Y1.00infobox
CycloserineChemSpider5998 Y1.00infobox
CycloserineCompTox Dashboard (EPA)DTXSID80228701.00infobox
CycloserineDrug classAntibiotic; Alanine racemase inhibitor; D-Alanine–D-alanine ligase inhibitor; NMDA receptor partial agonist; GABA-T inhibitor1.00infobox
CycloserineDrugBankDB00260 Y1.00infobox
CycloserineECHA InfoCard100.000.6261.00infobox
CycloserineElimination half-life10 hours (normal kidney function)1.00infobox
CycloserineExcretionKidney1.00infobox
CycloserineFormulaC3H6N2O21.00infobox
CycloserineKEGGD00877 Y1.00infobox
CycloserineLegal statusUS: ℞-only1.00infobox
CycloserineLicense dataUS DailyMed: Seromycin1.00infobox
CycloserineMelting point155 to 156 °C (311 to 313 °F) (dec.)1.00infobox
CycloserineMetabolismLiver1.00infobox
CycloserineMolar mass102.093 g·mol−11.00infobox
CycloserineNIAID ChemDB0076541.00infobox
CycloserineOther names.mw-parser-output span.smallcaps{font-variant:small-caps}.mw-parser-output span.smallcaps-smaller{font-size:85%}d-cycloserine, 4-amino-3-isoxazolidinone1.00infobox
CycloserinePubChem CID62341.00infobox
CycloserineRoutes of administrationOral1.00infobox
CycloserineTrade namesSeromycin1.00infobox
CycloserineUNII95IK5KI84Z1.00infobox
Cycloserineis astructural analogue of the amino acid D-alanine and works by inhibiting bacterial cell wall synthesis0.90text

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