Macrophage colony-stimulating factor

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around Macrophage colony-stimulating factor. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Function

Monocytes CSF1R Osteoblasts Endocrine Parathyroid hormone

11 related topics

As a drug target

PD-0360324 MCS110 CSF1R inhibitors

3 related topics

Clinical significance

Atherosclerosis Kidney failure

2 related topics

Interactions

Interact PIK3R2

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CSF1, CSF-1, MCSF, colony stimulating factor 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HMC, 3UEZ, 3UF2, 4ADF, 4FA8, 4WRL, 4WRM
Band: 1p13.3 · 3 F2.3|3 46.83 cM
Bgee: gallbladder · subcutaneous adipose tissue · right coronary artery · apex of heart · left adrenal gland
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 3 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Cytokine
Hematopoietic stem cells
Macrophages
Colony-stimulating factors Colony-stimulating factor
Colony stimulating factor 1 receptor
Placenta

Function

Clinical significance

As a drug target

PD-0360324 PD-0360324?action=edit&redlink=1
MCS110 MCS110?action=edit&redlink=1
CSF1R inhibitors CSF1R inhibitor

Interactions

Interact Protein-protein interaction
PIK3R2

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes30

Edges29

Triples132

Avg. degree1.93

Density0.066667

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Macrophage colony-stimulating factor

Top relations

Gene ontology · 56

Macrophage colony-stimulating factor → branching involved in mammary gland duct morphogenesis, cell differentiation, cell population proliferation, CSF1-CSF1R complex, cytokine activity, cytokine-mediated signaling pathway, developmental process involved in reproduction, endoplasmic reticulum lumen, extracellular region, extracellular space, growth factor activity, hemopoiesis, homeostasis of number of cells within a tissue, identical protein binding, immune system process, inflammatory response, innate immune response, integral component of membrane, macrophage colony-stimulating factor receptor binding, macrophage colony-stimulating factor signaling pathway

Bgee · 20

Macrophage colony-stimulating factor → ankle joint, aortic valve, apex of heart, ascending aorta, calvaria, cartilage tissue, endothelial cell of lymphatic vessel, gallbladder, left adrenal cortex, left adrenal gland, left coronary artery, mesenteric lymph nodes, right adrenal cortex, right adrenal gland, right coronary artery, secondary oocyte, stroma of bone marrow, subcutaneous adipose tissue, supraoptic nucleus, zygote

RNA expression pattern · 20

related to External links · 11

Macrophage colony-stimulating factor → Colony-Stimulating, Factor, Macrophage, Medicine Medical Subject Headings, MeSH, National Library, Overview, P09603, PDB, PDBe-KB, UniProt

Band · 2

Macrophage colony-stimulating factor → 1p13.3, 3 F2.3|3 46.83 cM

Chr. · 2

Macrophage colony-stimulating factor → Chromosome 1 (human), Chromosome 3 (mouse)

End · 2

Macrophage colony-stimulating factor → 107,667,785 bp, 109,930,992 bp

related to Interactions · 2

Macrophage colony-stimulating factor → Macrophage, PIK3R2

Aliases · 1

Macrophage colony-stimulating factor → CSF1, CSF-1, MCSF, colony stimulating factor 1

Available structures · 1

Macrophage colony-stimulating factor → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HMC, 3UEZ, 3UF2, 4ADF, 4FA8, 4WRL, 4WRM

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

m-csf factor also bp macrophage colony-stimulating cell chr human band csf1 receptor involved development csf1r stimulating cells chromosome csf-1 gene

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Macrophage colony-stimulating factor	Aliases	CSF1, CSF-1, MCSF, colony stimulating factor 1	1.00	infobox
Macrophage colony-stimulating factor	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HMC, 3UEZ, 3UF2, 4ADF, 4FA8, 4WRL, 4WRM	1.00	infobox
Macrophage colony-stimulating factor	Band	1p13.3	1.00	infobox
Macrophage colony-stimulating factor	Band	3 F2.3\|3 46.83 cM	1.00	infobox
Macrophage colony-stimulating factor	Bgee	gallbladder	1.00	infobox
Macrophage colony-stimulating factor	Bgee	subcutaneous adipose tissue	1.00	infobox
Macrophage colony-stimulating factor	Bgee	right coronary artery	1.00	infobox
Macrophage colony-stimulating factor	Bgee	apex of heart	1.00	infobox
Macrophage colony-stimulating factor	Bgee	left adrenal gland	1.00	infobox
Macrophage colony-stimulating factor	Bgee	left coronary artery	1.00	infobox
Macrophage colony-stimulating factor	Bgee	cartilage tissue	1.00	infobox
Macrophage colony-stimulating factor	Bgee	right adrenal gland	1.00	infobox
Macrophage colony-stimulating factor	Bgee	right adrenal cortex	1.00	infobox
Macrophage colony-stimulating factor	Bgee	left adrenal cortex	1.00	infobox
Macrophage colony-stimulating factor	Bgee	stroma of bone marrow	1.00	infobox
Macrophage colony-stimulating factor	Bgee	aortic valve	1.00	infobox
Macrophage colony-stimulating factor	Bgee	ascending aorta	1.00	infobox
Macrophage colony-stimulating factor	Bgee	mesenteric lymph nodes	1.00	infobox
Macrophage colony-stimulating factor	Bgee	calvaria	1.00	infobox
Macrophage colony-stimulating factor	Bgee	endothelial cell of lymphatic vessel	1.00	infobox
Macrophage colony-stimulating factor	Bgee	ankle joint	1.00	infobox
Macrophage colony-stimulating factor	Bgee	zygote	1.00	infobox
Macrophage colony-stimulating factor	Bgee	secondary oocyte	1.00	infobox
Macrophage colony-stimulating factor	Bgee	supraoptic nucleus	1.00	infobox
Macrophage colony-stimulating factor	BioGPS	More reference expression data	1.00	infobox
Macrophage colony-stimulating factor	Chr.	Chromosome 1 (human)	1.00	infobox
Macrophage colony-stimulating factor	Chr.	Chromosome 3 (mouse)	1.00	infobox
Macrophage colony-stimulating factor	Databases	NCBI: entry; OMA: entry	1.00	infobox
Macrophage colony-stimulating factor	End	109,930,992 bp	1.00	infobox
Macrophage colony-stimulating factor	End	107,667,785 bp	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3