CRYAB

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CRYAB topic overview

The analysis highlights Art, Interactions and Structure as prominent areas in the source structure around CRYAB.

Related topics: 14
Source areas: 5
Connected nodes: 19
Extracted relationships: 144
Concept neighborhoods: 8
Bridge connections: 19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 7 topics

Clinical significance · 2 topics

Overview · 2 topics

Structure · 2 topics

Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2, crystallin alpha B
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07
Band: 11q23.1 · 9 A5.3|9 27.75 cM
Bgee: myocardium of left ventricle · middle frontal gyrus · right auricle of heart · C1 segment · olfactory bulb
BioGPS: More reference expression data
Chr.: Chromosome 11 (human) · Chromosome 9 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Crystallins Crystallin
Alpha crystallins Alpha crystallin

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CRYAB connects Entity context

The extracted context around CRYAB shows recurring relationship patterns in the source. For example, CRYAB → actin filament bundle, ageing, amyloid-beta binding, apoptotic process involved in morphogenesis, axon, camera-type eye development, cardiac myofibril, cell surface, cellular response to gamma radiation, contractile fiber, cytoplasm, cytoskeletal protein binding, cytosol, dendritic spine, extracellular exosome, Golgi apparatus, I band, identical protein binding, lens development in camera-type eye, M band Another extracted example is CRYAB → apex of heart, C1 segment, ciliary body, epithelium of lens, gastrula, inferior ganglion of vagus nerve, intercostal muscle, iris, masseter muscle, middle frontal gyrus, muscle of thigh, myocardium of left ventricle, myocardium of ventricle, olfactory bulb, optic nerve, retinal pigment epithelium, right auricle of heart, right ventricle, sciatic nerve, soleus muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 61

CRYAB → actin filament bundle, ageing, amyloid-beta binding, apoptotic process involved in morphogenesis, axon, camera-type eye development, cardiac myofibril, cell surface, cellular response to gamma radiation, contractile fiber, cytoplasm, cytoskeletal protein binding, cytosol, dendritic spine, extracellular exosome, Golgi apparatus, I band, identical protein binding, lens development in camera-type eye, M band

Bgee · 20

CRYAB → apex of heart, C1 segment, ciliary body, epithelium of lens, gastrula, inferior ganglion of vagus nerve, intercostal muscle, iris, masseter muscle, middle frontal gyrus, muscle of thigh, myocardium of left ventricle, myocardium of ventricle, olfactory bulb, optic nerve, retinal pigment epithelium, right auricle of heart, right ventricle, sciatic nerve, soleus muscle

RNA expression pattern · 20

related to Clinical significance · 10

CRYAB → Although, Alzheimer’s, ER, ER-anchored, HNSCC, Mutations, Parkinson’s, The, Though, Thus

related to Interactions · 5

CRYAB → CRYAA, CRYBB2, CRYGC, Hsp27, HSPB2

Band · 2

CRYAB → 11q23.1, 9 A5.3|9 27.75 cM

Chr. · 2

CRYAB → Chromosome 11 (human), Chromosome 9 (mouse)

End · 2

CRYAB → 111,923,722 bp, 50,667,936 bp

Aliases · 1

CRYAB → CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2, crystallin alpha B

Available structures · 1

CRYAB → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

protein gene crystallins bp chr human band alpha lens αbc also chaperone chromosome 11 heat proteins disease expression molecular intracellular

CRYAB relationships Subject–Predicate–Object triples

TTTA extracted 144 structured relationships around CRYAB. Examples in this analysis include CRYAB → Aliases → CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2, crystallin alpha B and CRYAB → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CRYAB	Aliases	CRYAB, CMD1II, CRYA2, CTPP2, CTRCT16, HEL-S-101, HSPB5, MFM2, crystallin alpha B	1.00	infobox
CRYAB	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KLR, 2N0K, 2WJ7, 2Y1Y, 2Y1Z, 2Y22, 2YGD, 3L1G, 3SGM, 3SGN, 3SGO, 3SGP, 3SGR, 3SGS, 4M5S, 4M5T, 3J07	1.00	infobox
CRYAB	Band	11q23.1	1.00	infobox
CRYAB	Band	9 A5.3\|9 27.75 cM	1.00	infobox
CRYAB	Bgee	myocardium of left ventricle	1.00	infobox
CRYAB	Bgee	middle frontal gyrus	1.00	infobox
CRYAB	Bgee	right auricle of heart	1.00	infobox
CRYAB	Bgee	C1 segment	1.00	infobox
CRYAB	Bgee	olfactory bulb	1.00	infobox
CRYAB	Bgee	apex of heart	1.00	infobox
CRYAB	Bgee	muscle of thigh	1.00	infobox
CRYAB	Bgee	optic nerve	1.00	infobox
CRYAB	Bgee	inferior ganglion of vagus nerve	1.00	infobox
CRYAB	Bgee	right ventricle	1.00	infobox
CRYAB	Bgee	epithelium of lens	1.00	infobox
CRYAB	Bgee	ciliary body	1.00	infobox
CRYAB	Bgee	iris	1.00	infobox
CRYAB	Bgee	myocardium of ventricle	1.00	infobox
CRYAB	Bgee	soleus muscle	1.00	infobox
CRYAB	Bgee	sciatic nerve	1.00	infobox
CRYAB	Bgee	gastrula	1.00	infobox
CRYAB	Bgee	intercostal muscle	1.00	infobox
CRYAB	Bgee	retinal pigment epithelium	1.00	infobox
CRYAB	Bgee	masseter muscle	1.00	infobox
CRYAB	BioGPS	More reference expression data	1.00	infobox
CRYAB	Chr.	Chromosome 11 (human)	1.00	infobox
CRYAB	Chr.	Chromosome 9 (mouse)	1.00	infobox
CRYAB	Databases	NCBI: entry; OMA: entry	1.00	infobox
CRYAB	End	111,923,722 bp	1.00	infobox
CRYAB	End	50,667,936 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CRYAB bring nearby vocabulary together. In this analysis, examples include Function, Gene and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CRYAB
- Function
- Gene
- Location
- Chromosome
- Human
- Also
- Bp
- Chr
- External
- Mouse
- Protein
- Activity
cryab
- Function
- Gene
- Location
- Chromosome
- Human
- Also
- Bp
- Chr
- External
- Mouse
- Protein
- Activity
protein
- Molecular
- Disease
- Crystallins
- Activity
- Development
- Diseases
- Intracellular
- Shock
- Proteins
- Αbc
- Cancer
- Function
gene
- Location
- Chromosome
- Human
- Bp
- Chr
- Function
- Mouse
- Alpha-a
- Expressed
- Two
- Alpha-b
- Band
alpha crystallins
- Crystallins
- Two
- Lens
- Development
- Intracellular
- Also
- Heat
- Protein
- Gene
- External
- Function
- Activity
heat shock protein
- Shock
- Family
- Intracellular
- Molecular
- Expression
- Αbc
- Disease
- Protein
- Well
- Crystallins
- Cells
- Function
crystallins
- Two
- Lens
- Development
- Intracellular
- Heat
- Protein
- Gene
- Function
- Mouse
- Alpha-a
- Cells
- Expressed
function
- Location
- Chromosome
- Human
- Bp
- Chr
- Mouse
- Gene
- Activity
- Development
- Expressed
- Eye
- Formation

Connections between topic areas Semantic bridges

For CRYAB, one of the stronger structural bridges in this analysis connects CRYAB with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CRYAB — Interactions · splits 12 ⟂ 8

CRYAB — Overview · splits 17 ⟂ 3

CRYAB — Structure · splits 17 ⟂ 3

CRYAB — Clinical significance · splits 17 ⟂ 3

Map overview Semantic statistics

CRYAB

Nodes20

Edges19

Triples144

Avg. degree1.9

Density0.1

Components1

Source & methodology

TTTA analyzes the structure around CRYAB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interactions & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CRYAB · EN edition · Analysis: TopicsToTalkAbout