Cytochrome c oxidase subunit 2

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Clinical significance

Mitochondrial Heterogeneous Phenotypes Myopathy Multisystem disease

38 related topics

Structure

P arm Amino acids EC Complex Mitochondrial respiratory chain

18 related topics

Function

Reduction Water Catalytic subunit 1 N-terminus Intermembrane space

6 related topics

Interactions

Carboxyl Heme edge

2 related topics

Key facts & relationships

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7.1.1.9: ↗
Aliases: COX2, mitochondrially encoded cytochrome c oxidase II, COII, MTCO2, Cytochrome c oxidase subunit II, CO II
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3VRJ
Band: n/a
Bgee: mucosa of transverse colon · putamen · caudate nucleus · right frontal lobe · nucleus accumbens
BioGPS: n/a

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Overview

Protein
Eukaryotes Eukaryote
Gene
Cytochrome c oxidase
Mitochondrial DNA
MT-CO1
MT-CO3
Respiratory complex IV Electron transport chain

Structure

Function

Reduction Reduction (chemistry)
Water
Catalytic subunit 1 Cytochrome c oxidase subunit I
N-terminus
Intermembrane space
Binuclear copper A center Copper proteins

Interactions

Carboxyl
Heme edge Hemeprotein

Advanced semantic analysis

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Map overview Semantic statistics

Nodes78

Edges77

Triples102

Avg. degree1.97

Density0.025641

Components1

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Cytochrome c oxidase subunit 2

Top relations

Gene ontology · 22

Cytochrome c oxidase subunit 2 → ATP synthesis coupled electron transport, copper ion binding, cytochrome-c oxidase activity, electron transport chain, extracellular exosome, integral component of membrane, lactation, membrane, metal ion binding, mitochondrial electron transport, cytochrome c to oxygen, mitochondrial inner membrane, mitochondrial respiratory chain complex IV, mitochondrion, oxidoreductase activity, positive regulation of ATP biosynthetic process, positive regulation of hydrogen peroxide biosynthetic process, positive regulation of necrotic cell death, protein binding, proton transmembrane transport, respirasome

Bgee · 20

Cytochrome c oxidase subunit 2 → caudate nucleus, dentate gyrus of hippocampal formation granule cell, duodenum, epiblast, esophagus, hippocampus proper, hypothalamus, jejunum, mucosa of transverse colon, muscle layer of sigmoid colon, nucleus accumbens, ovary, proximal tubule, putamen, right frontal lobe, right hemisphere of cerebellum, right kidney, substantia nigra, ventricular zone, zone of skin

RNA expression pattern · 20

Chr. · 2

Cytochrome c oxidase subunit 2 → Mitochondrial DNA (human), Mitochondrial DNA (mouse)

End · 2

Cytochrome c oxidase subunit 2 → 7,696 bp, 8,269 bp

7.1.1.9 · 1

Cytochrome c oxidase subunit 2 → ↗

Aliases · 1

Cytochrome c oxidase subunit 2 → COX2, mitochondrially encoded cytochrome c oxidase II, COII, MTCO2, Cytochrome c oxidase subunit II, CO II

Available structures · 1

Cytochrome c oxidase subunit 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3VRJ

Band · 1

Cytochrome c oxidase subunit 2 → n/a

BioGPS · 1

Cytochrome c oxidase subunit 2 → n/a

Important terminology Word statistics

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Important terminology

mt-co2 mitochondrial cytochrome gene complex oxidase iv dna bp chr human band enzyme subunit respiratory protein deficiency ii encoded oxygen

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Cytochrome c oxidase subunit 2	7.1.1.9	↗	1.00	infobox
Cytochrome c oxidase subunit 2	Aliases	COX2, mitochondrially encoded cytochrome c oxidase II, COII, MTCO2, Cytochrome c oxidase subunit II, CO II	1.00	infobox
Cytochrome c oxidase subunit 2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3VRJ	1.00	infobox
Cytochrome c oxidase subunit 2	Band	n/a	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	mucosa of transverse colon	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	putamen	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	caudate nucleus	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	right frontal lobe	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	nucleus accumbens	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	right hemisphere of cerebellum	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	hippocampus proper	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	substantia nigra	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	muscle layer of sigmoid colon	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	hypothalamus	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	ventricular zone	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	esophagus	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	zone of skin	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	ovary	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	epiblast	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	jejunum	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	right kidney	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	proximal tubule	1.00	infobox
Cytochrome c oxidase subunit 2	Bgee	duodenum	1.00	infobox
Cytochrome c oxidase subunit 2	BioGPS	n/a	1.00	infobox
Cytochrome c oxidase subunit 2	Chr.	Mitochondrial DNA (human)	1.00	infobox
Cytochrome c oxidase subunit 2	Chr.	Mitochondrial DNA (mouse)	1.00	infobox
Cytochrome c oxidase subunit 2	Databases	NCBI: entry; OMA: entry	1.00	infobox
Cytochrome c oxidase subunit 2	End	8,269 bp	1.00	infobox
Cytochrome c oxidase subunit 2	End	7,696 bp	1.00	infobox

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