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Ciliary neurotrophic factor: Applications & Regions

Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene.

Language: English [EN]
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Ciliary neurotrophic factor topic overview

The analysis highlights Applications and Regions as prominent areas in the source structure around Ciliary neurotrophic factor.

Related topics
45
Source areas
3
Connected nodes
48
Extracted relationships
106
Concept neighborhoods
9
Bridge connections
48

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 22 topics
Therapeutic applications · 21 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CNTF, Hciliary neurotrophic factor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CNT
Band
11q12.1 · 19 A|19 8.73 cM
Bgee
testicle · tibial nerve · C1 segment · sural nerve · gastrocnemius muscle
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Therapeutic applications

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Ciliary neurotrophic factor connects Entity context

The extracted context around Ciliary neurotrophic factor shows recurring relationship patterns in the source. For example, Ciliary neurotrophic factor → astrocyte activation, axon, cell differentiation, ciliary neurotrophic factor receptor binding, ciliary neurotrophic factor-mediated signaling pathway, CRLF-CLCF1 complex, cytokine activity, cytokine-mediated signaling pathway, cytoplasm, extracellular region, extracellular space, growth, growth factor activity, interleukin-6 receptor binding, multicellular organism development, muscle organ morphogenesis, negative regulation of neuron apoptotic process, negative regulation of photoreceptor cell differentiation, nervous system development, neuron development Another extracted example is Ciliary neurotrophic factor → blastocyst, bone marrow, C1 segment, embryo, gastrocnemius muscle, hair, lens, monocyte, morula, muscle of thigh, olfactory zone of nasal mucosa, pallidum of neuraxis, salivary gland, substantia nigra, sural nerve, tail of embryo, testicle, tibial nerve. Use these groups to spot repeated connection types before inspecting the individual relationships.

Ciliary neurotrophic factor

Top relations

Gene ontology · 29
Ciliary neurotrophic factor → astrocyte activation, axon, cell differentiation, ciliary neurotrophic factor receptor binding, ciliary neurotrophic factor-mediated signaling pathway, CRLF-CLCF1 complex, cytokine activity, cytokine-mediated signaling pathway, cytoplasm, extracellular region, extracellular space, growth, growth factor activity, interleukin-6 receptor binding, multicellular organism development, muscle organ morphogenesis, negative regulation of neuron apoptotic process, negative regulation of photoreceptor cell differentiation, nervous system development, neuron development
Bgee · 18
Ciliary neurotrophic factor → blastocyst, bone marrow, C1 segment, embryo, gastrocnemius muscle, hair, lens, monocyte, morula, muscle of thigh, olfactory zone of nasal mucosa, pallidum of neuraxis, salivary gland, substantia nigra, sural nerve, tail of embryo, testicle, tibial nerve
RNA expression pattern · 18
Ciliary neurotrophic factor → blastocyst, bone marrow, C1 segment, embryo, gastrocnemius muscle, hair, lens, monocyte, morula, muscle of thigh, olfactory zone of nasal mucosa, pallidum of neuraxis, salivary gland, substantia nigra, sural nerve, tail of embryo, testicle, tibial nerve
related to External links · 9
Ciliary neurotrophic factor → Ciliary, Medicine Medical Subject Headings, MeSH, National Library, Overview, P26441, PDB, PDBe-KB, UniProt
related to NT-501 · 4
Ciliary neurotrophic factor → CNTF, In, Neurotech, NT-501
Band · 2
Ciliary neurotrophic factor → 11q12.1, 19 A|19 8.73 cM
Chr. · 2
Ciliary neurotrophic factor → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
Ciliary neurotrophic factor → 12,742,996 bp, 58,625,733 bp
related to Interactions · 2
Ciliary neurotrophic factor → Human, Interleukin
see also · 2
Ciliary neurotrophic factor → Ciliary, YancopoulosPeptide

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

factor cntf neurotrophic gene human ciliary bp protein chr band subjects chromosome 11 axokine also location cells weight may encoded

Ciliary neurotrophic factor relationships Subject–Predicate–Object triples

TTTA extracted 106 structured relationships around Ciliary neurotrophic factor. Examples in this analysis include Ciliary neurotrophic factor → Aliases → CNTF, Hciliary neurotrophic factor and Ciliary neurotrophic factor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CNT. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Ciliary neurotrophic factorAliasesCNTF, Hciliary neurotrophic factor1.00infobox
Ciliary neurotrophic factorAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CNT1.00infobox
Ciliary neurotrophic factorBand11q12.11.00infobox
Ciliary neurotrophic factorBand19 A|19 8.73 cM1.00infobox
Ciliary neurotrophic factorBgeetesticle1.00infobox
Ciliary neurotrophic factorBgeetibial nerve1.00infobox
Ciliary neurotrophic factorBgeeC1 segment1.00infobox
Ciliary neurotrophic factorBgeesural nerve1.00infobox
Ciliary neurotrophic factorBgeegastrocnemius muscle1.00infobox
Ciliary neurotrophic factorBgeesubstantia nigra1.00infobox
Ciliary neurotrophic factorBgeemonocyte1.00infobox
Ciliary neurotrophic factorBgeemuscle of thigh1.00infobox
Ciliary neurotrophic factorBgeeolfactory zone of nasal mucosa1.00infobox
Ciliary neurotrophic factorBgeebone marrow1.00infobox
Ciliary neurotrophic factorBgeelens1.00infobox
Ciliary neurotrophic factorBgeemorula1.00infobox
Ciliary neurotrophic factorBgeeembryo1.00infobox
Ciliary neurotrophic factorBgeetail of embryo1.00infobox
Ciliary neurotrophic factorBgeeblastocyst1.00infobox
Ciliary neurotrophic factorBgeesalivary gland1.00infobox
Ciliary neurotrophic factorBgeehair1.00infobox
Ciliary neurotrophic factorBgeepallidum of neuraxis1.00infobox
Ciliary neurotrophic factorBioGPSMore reference expression data1.00infobox
Ciliary neurotrophic factorChr.Chromosome 11 (human)1.00infobox
Ciliary neurotrophic factorChr.Chromosome 19 (mouse)1.00infobox
Ciliary neurotrophic factorDatabasesNCBI: entry; OMA: entry1.00infobox
Ciliary neurotrophic factorEnd58,625,733 bp1.00infobox
Ciliary neurotrophic factorEnd12,742,996 bp1.00infobox
Ciliary neurotrophic factorEnsemblENSG000002426891.00infobox
Ciliary neurotrophic factorEntrez12701.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Ciliary neurotrophic factor bring nearby vocabulary together. In this analysis, examples include Neurotrophic, Factor and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Ciliary neurotrophic factor
    • Neurotrophic
    • Factor
    • Receptor
    • Protein
    • Gene
    • Human
    • P26441
    • Region
    • Results
    • Uniprot
    • Cntf
    • Cells
  • ciliary neurotrophic factor
    • Neurotrophic
    • Factor
    • Gene
    • Receptor
    • Protein
    • Cntf
    • Human
    • P26441
    • Region
    • Results
    • Uniprot
    • Encoded
  • gene
    • Location
    • Neurotrophic
    • Chromosome
    • Protein
    • Bp
    • Chr
    • Mouse
    • Nervous
    • System
    • Human
    • Also
    • Band
  • neurotrophic factor
    • Neurotrophic
    • Gene
    • Protein
    • Cntf
    • Human
    • Receptor
    • Encoded
    • Nervous
    • P26441
    • Pdb
    • Region
    • Results
  • bone
    • Activity
    • Expressed
    • Mouse
    • Nervous
    • P26441
    • Region
    • System
    • Uniprot
    • Cells
    • Location
    • Loss
    • Receptor
  • protein
    • Region
    • System
    • Activity
    • Bone
    • Expressed
    • Mouse
    • P26441
    • Results
    • Transcript
    • Uniprot
    • Location
    • Loss
  • coding region
    • Activity
    • Bone
    • Expressed
    • Mouse
    • P26441
    • Results
    • System
    • Transcript
    • Uniprot
    • Location
    • Loss
    • Receptor
  • cells
    • Cntf
    • Activity
    • Bone
    • Expressed
    • May
    • Modified
    • Nt-501
    • Neurotrophic
    • Factor
    • Human
    • Ciliary

Connections between topic areas Semantic bridges

For Ciliary neurotrophic factor, one of the stronger structural bridges in this analysis connects Ciliary neurotrophic factor with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Ciliary neurotrophic factorOverview · splits 26 ⟂ 23
Ciliary neurotrophic factorTherapeutic applications · splits 27 ⟂ 22
Ciliary neurotrophic factorInteractions · splits 46 ⟂ 3

Map overview Semantic statistics

Ciliary neurotrophic factor

Nodes49
Edges48
Triples106
Avg. degree1.96
Density0.040816
Components1

Source & methodology

TTTA analyzes the structure around Ciliary neurotrophic factor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Ciliary neurotrophic factor · EN edition · Analysis: TopicsToTalkAbout

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