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Cdc25: Standards, Evolution and species distribution & Function in activating Cdk1

Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle proteins or genes such as Cdc2 and Cdc4, the "cdc" in its name refers to "cell division cycle". Dual-specificity phosphatases are considered a sub-class of protein tyrosine phosphatases. By removing…

Language: English [EN]
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Cdc25 topic overview

The analysis highlights Standards, Evolution and species distribution and Function in activating Cdk1 as prominent areas in the source structure around Cdc25.

Related topics
28
Source areas
5
Connected nodes
33
Extracted relationships
67
Concept neighborhoods
15
Bridge connections
33

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Evolution and species distribution · 11 topics
Overview · 8 topics
Function in activating Cdk1 · 4 topics
In human disease · 4 topics
Knockout models · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
Cdc25 phosphatase
Databases
n/a
Ensembl
n/a
Entrez
n/a
External IDs
OMIM: 157680; GeneCards:
Location (UCSC)
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function in activating Cdk1

Evolution and species distribution

Knockout models

  • Myt1 Myt1?action=edit&redlink=1

In human disease

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cdc25 connects Entity context

The extracted context around Cdc25 shows recurring relationship patterns in the source. For example, Cdc25 → An, Caenorhabditis, Cdc-25, Cdc25A, Cdc25B, Cdc25C, Cdc25s, Drosophila, Ibp1, Itsy-bitsy, Most, The, The Cdc25, Yeasts Another extracted example is Cdc25 → Cdc25A-C, Cdk, Cdk1, G1, G2, In, M-Cdk, The, The Cdc25, Together, Wee1. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cdc25

Top relations

related to Evolution and species distribution · 14
Cdc25 → An, Caenorhabditis, Cdc-25, Cdc25A, Cdc25B, Cdc25C, Cdc25s, Drosophila, Ibp1, Itsy-bitsy, Most, The, The Cdc25, Yeasts
related to Function in activating Cdk1 · 11
Cdc25 → Cdc25A-C, Cdk, Cdk1, G1, G2, In, M-Cdk, The, The Cdc25, Together, Wee1
related to In human disease · 10
Cdc25 → ADME, Although, Cdc25 Inhibitors, Cdc25A, Cdc25B, Cdc25s, It, The, The Cdc25s, To
related to Knockout models · 9
Cdc25 → Although, Cdc25A, Cdc25B, Cdc25C, Cdc25s, Cdk, Hiroaki Kiyokawa's, Myt1, Wee1
related to Structure · 3
Cdc25 → C-terminal, N-terminal, The
related to Genes · 2
Cdc25 → CDC25A1C25 Human, PDBCDC25BCDC25C
Aliases · 1
Cdc25 → Cdc25 phosphatase
Databases · 1
Cdc25 → n/a
Ensembl · 1
Cdc25 → n/a
Entrez · 1
Cdc25 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cell cycle cdc25a cdc25s proteins phosphatase cdc25b dual-specificity mitosis genes protein human enzymes phosphate control including cyclin cdc25c knockout species

Cdc25 relationships Subject–Predicate–Object triples

TTTA extracted 67 structured relationships around Cdc25. Examples in this analysis include Cdc25 → Aliases → Cdc25 phosphatase and Cdc25 → Databases → n/a. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cdc25AliasesCdc25 phosphatase1.00infobox
Cdc25Databasesn/a1.00infobox
Cdc25Ensembln/a1.00infobox
Cdc25Entrezn/a1.00infobox
Cdc25External IDsOMIM: 157680; GeneCards:1.00infobox
Cdc25Location (UCSC)n/a1.00infobox
Cdc25OrthologsOrthologsDatabasesn/aSpeciesHumanMouseEntrezn/an/aEnsembln/an/aUniProtn an/aRefSeq (mRNA)n/an/aRefSeq (protein)n/an/aLocation (UCSC)n/an/aPubMed searchn/an/a1.00infobox
Cdc25PubMed searchn/a1.00infobox
Cdc25RefSeq (mRNA)n/a1.00infobox
Cdc25RefSeq (protein)n/a1.00infobox
Cdc25SpeciesHuman1.00infobox
Cdc25UniProtn a1.00infobox
Cdc25is adual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cdc25 bring nearby vocabulary together. In this analysis, examples include Phosphatase, Including and Phosphate. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cdc25
    • Phosphatase
    • Including
    • Phosphate
    • Site
    • Proteins
    • Cdk1
    • Isolated
    • Kinases
    • Phase
    • Removing
    • Residues
    • Structure
  • cdc25
    • Phosphatase
    • Including
    • Phosphate
    • Site
    • Proteins
    • Cdk1
    • Isolated
    • Kinases
    • Phase
    • Removing
    • Residues
    • Structure
  • cell cycle
    • Cycle
    • Proteins
    • Cdc25s
    • Entry
    • Isolated
    • Kinases
    • Phase
    • Removing
    • Residues
    • Target
    • Various
    • Control
  • cyclin dependent kinases
    • Removing
    • Residues
    • Human
    • Phosphate
    • External
    • Species
    • Cdk1
    • Entry
    • Phase
    • Structure
    • Target
    • Various
  • cyclin-dependent kinases
    • Removing
    • Residues
    • Phosphate
    • External
    • Species
    • Cdk1
    • Entry
    • Human
    • Phase
    • Structure
    • Target
    • Various
  • knockout models
    • Viable
    • Cdc25a
    • External
    • Species
    • Human
    • Removing
    • Residues
    • Structure
    • Activity
    • Cdc25c
    • Cyclin
    • Family
  • dual-specificity phosphatase
    • Phosphatases
    • Structure
    • Site
    • Isolated
    • Species
    • Protein
    • Removing
    • Residues
    • Activity
    • Cycle
    • Cyclin
    • Known
  • cyclin b
    • Human
    • External
    • Species
    • Kinases
    • Removing
    • Residues
    • Structure
    • Cdc25c
    • Genes
    • Knockout
    • Phosphate
    • Protein

Connections between topic areas Semantic bridges

For Cdc25, one of the stronger structural bridges in this analysis connects Cdc25 with Evolution and species distribution. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cdc25 — Evolution and species distribution · splits 22 ⟂ 12
Cdc25 — Overview · splits 25 ⟂ 9
Cdc25 — Function in activating Cdk1 · splits 29 ⟂ 5
Cdc25 — In human disease · splits 29 ⟂ 5

Map overview Semantic statistics

Cdc25

Nodes34
Edges33
Triples67
Avg. degree1.94
Density0.058824
Components1

Source & methodology

TTTA analyzes the structure around Cdc25 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Evolution and species distribution & Function in activating Cdk1, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cdc25 · EN edition · Analysis: TopicsToTalkAbout

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