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Cdc25

Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle proteins or genes such as Cdc2 and Cdc4, the "cdc" in its name refers to "cell division cycle". Dual-specificity phosphatases are considered a sub-class of protein tyrosine phosphatases. By removing…

Standards, Evolution and species distribution & Function in activating Cdk1

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Evolution and species distribution

FungiYeastsMetazoansPlantsIbp1
11 related topics

Function in activating Cdk1

Cyclin dependent kinasesCdk1Cyclin BWee1
4 related topics

In human disease

OncogenesCancerPharmaceuticalChemotherapeutic
4 related topics

Knockout models

Myt1
1 related topics

Key facts & relationships

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Aliases
Cdc25 phosphatase
Databases
n/a
Ensembl
n/a
Entrez
n/a
External IDs
OMIM: 157680; GeneCards:
Location (UCSC)
n/a

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Overview

Function in activating Cdk1

Evolution and species distribution

Knockout models

  • Myt1 Myt1?action=edit&redlink=1

In human disease

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Map overview Semantic statistics

Cdc25

Nodes34
Edges33
Triples67
Avg. degree1.94
Density0.058824
Components1

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Cdc25

Top relations

related to Evolution and species distribution · 14
Cdc25 → An, Caenorhabditis, Cdc-25, Cdc25A, Cdc25B, Cdc25C, Cdc25s, Drosophila, Ibp1, Itsy-bitsy, Most, The, The Cdc25, Yeasts
related to Function in activating Cdk1 · 11
Cdc25 → Cdc25A-C, Cdk, Cdk1, G1, G2, In, M-Cdk, The, The Cdc25, Together, Wee1
related to In human disease · 10
Cdc25 → ADME, Although, Cdc25 Inhibitors, Cdc25A, Cdc25B, Cdc25s, It, The, The Cdc25s, To
related to Knockout models · 9
Cdc25 → Although, Cdc25A, Cdc25B, Cdc25C, Cdc25s, Cdk, Hiroaki Kiyokawa's, Myt1, Wee1
related to Structure · 3
Cdc25 → C-terminal, N-terminal, The
related to Genes · 2
Cdc25 → CDC25A1C25 Human, PDBCDC25BCDC25C
Aliases · 1
Cdc25 → Cdc25 phosphatase
Databases · 1
Cdc25 → n/a
Ensembl · 1
Cdc25 → n/a
Entrez · 1
Cdc25 → n/a

Important terminology Word statistics

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Important terminology

cell cycle cdc25a cdc25s proteins phosphatase cdc25b dual-specificity mitosis genes protein human enzymes phosphate control including cyclin cdc25c knockout species

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cdc25AliasesCdc25 phosphatase1.00infobox
Cdc25Databasesn/a1.00infobox
Cdc25Ensembln/a1.00infobox
Cdc25Entrezn/a1.00infobox
Cdc25External IDsOMIM: 157680; GeneCards:1.00infobox
Cdc25Location (UCSC)n/a1.00infobox
Cdc25OrthologsOrthologsDatabasesn/aSpeciesHumanMouseEntrezn/an/aEnsembln/an/aUniProtn an/aRefSeq (mRNA)n/an/aRefSeq (protein)n/an/aLocation (UCSC)n/an/aPubMed searchn/an/a1.00infobox
Cdc25PubMed searchn/a1.00infobox
Cdc25RefSeq (mRNA)n/a1.00infobox
Cdc25RefSeq (protein)n/a1.00infobox
Cdc25SpeciesHuman1.00infobox
Cdc25UniProtn a1.00infobox
Cdc25is adual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant0.90text

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