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CD2

CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor.

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Aliases
CD2, LFA-2, SRBC, T11, CD2 molecule
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CDB, 1GYA, 1HNF, 1L2Z, 1QA9, 2J6O, 2J7I
Band
1p13.1 · 3 F2.2|3 44.17 cM
Bgee
granulocyte · thymus · lymph node · testicle · appendix
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)

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Map overview Semantic statistics

CD2

Nodes21
Edges20
Triples104
Avg. degree1.9
Density0.095238
Components1

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CD2

Top relations

Gene ontology · 32
CD2 → anchored component of plasma membrane, antigen binding, apoptotic process, cell adhesion, cell surface, cell surface receptor signaling pathway, cell-cell adhesion, cell-cell junction, cytoplasmic side of plasma membrane, external side of plasma membrane, extracellular region, heterotypic cell-cell adhesion, integral component of membrane, integral component of plasma membrane, leukocyte migration, membrane, membrane raft, membrane raft polarization, natural killer cell activation, plasma membrane
Bgee · 15
CD2 → ankle joint, appendix, blood, embryo, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, mucosa of ileum, right lung lobe, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, thymus
RNA expression pattern · 15
CD2 → ankle joint, appendix, blood, embryo, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, mucosa of ileum, right lung lobe, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, thymus
related to External links · 7
CD2 → Antigen, CD Antigen ChartHuman CD2, Medicine Medical Subject Headings, MeSH, Mouse CD Antigen ChartHuman, National Library, UCSC Genome Browser
related to Function · 5
CD2 → CD48, In, It, LFA-3/CD58, NK
related to Interactions · 3
CD2 → CD2BP2, Lck, PSTPIP1
Band · 2
CD2 → 1p13.1, 3 F2.2|3 44.17 cM
Chr. · 2
CD2 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
CD2 → 101,195,255 bp, 116,769,229 bp
related to Diagnostic relevance · 2
CD2 → NK, The

Important terminology Word statistics

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Important terminology

bp human chr band antigen chromosome gene location surface cells external mouse cell adhesion molecule nk also differentiation natural killer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CD2AliasesCD2, LFA-2, SRBC, T11, CD2 molecule1.00infobox
CD2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1CDB, 1GYA, 1HNF, 1L2Z, 1QA9, 2J6O, 2J7I1.00infobox
CD2Band1p13.11.00infobox
CD2Band3 F2.2|3 44.17 cM1.00infobox
CD2Bgeegranulocyte1.00infobox
CD2Bgeethymus1.00infobox
CD2Bgeelymph node1.00infobox
CD2Bgeetesticle1.00infobox
CD2Bgeeappendix1.00infobox
CD2Bgeeblood1.00infobox
CD2Bgeeepithelium of nasopharynx1.00infobox
CD2Bgeesuperficial temporal artery1.00infobox
CD2Bgeespleen1.00infobox
CD2Bgeemucosa of ileum1.00infobox
CD2Bgeemesenteric lymph nodes1.00infobox
CD2Bgeeright lung lobe1.00infobox
CD2Bgeesubcutaneous adipose tissue1.00infobox
CD2Bgeeembryo1.00infobox
CD2Bgeeankle joint1.00infobox
CD2BioGPSMore reference expression data1.00infobox
CD2Chr.Chromosome 1 (human)1.00infobox
CD2Chr.Chromosome 3 (mouse)1.00infobox
CD2DatabasesNCBI: entry; OMA: entry1.00infobox
CD2End116,769,229 bp1.00infobox
CD2End101,195,255 bp1.00infobox
CD2EnsemblENSG000001168241.00infobox
CD2Entrez9141.00infobox
CD2External IDsOMIM: 186990; MGI: 88320; GeneCards: CD21.00infobox
CD2Gene location (Human)Gene location (Human)Chr.Chromosome 1 (human)Band1p13.1Start116,754,430 bpEnd116,769,229 bp1.00infobox
CD2Gene location (Mouse)Gene location (Mouse)Chr.Chromosome 3 (mouse)Band3 F2.2|3 44.17 cMStart101,183,215 bpEnd101,195,255 bp1.00infobox

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