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Casdatifan is an investigational new drug that is being evaluated by Arcus Biosciences and AstraZeneca for the treatment of renal cell carcinoma. It is an inhibitor of endothelial PAS domain-containing protein 1 (HIF‑2α).
Science, Pharmacology & Clinical trials
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inhibitor treatment renal cell carcinoma hif 2α clinical trials astrazeneca investigational new drug evaluated arcus biosciences endothelial pas domain-containing protein
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Casdatifan | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Casdatifan | CAS Number | 2709069-30-5 | 1.00 | infobox |
| Casdatifan | ChEBI | CHEBI:760136 | 1.00 | infobox |
| Casdatifan | ChEMBL | ChEMBL6068220 | 1.00 | infobox |
| Casdatifan | DrugBank | DB21701 | 1.00 | infobox |
| Casdatifan | Formula | C21H17F4NO3S | 1.00 | infobox |
| Casdatifan | IUPHAR/BPS | 13981 | 1.00 | infobox |
| Casdatifan | KEGG | D13257 | 1.00 | infobox |
| Casdatifan | Molar mass | 439.42 g·mol−1 | 1.00 | infobox |
| Casdatifan | Other names | AB-521 | 1.00 | infobox |
| Casdatifan | PubChem CID | 156859185 | 1.00 | infobox |
| Casdatifan | UNII | DP73UWL6LE | 1.00 | infobox |
| Casdatifan | is a | investigational new drug that is being evaluated by Arcus Biosciences and AstraZeneca for the treatment of renal cell carcinoma | 0.90 | text |
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