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CACNG2: Measurement, Function & Interactions

Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin, is a protein that in humans is encoded by the CACNG2 gene.

Language: English [EN]
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CACNG2 topic overview

The analysis highlights Measurement, Function and Interactions as prominent areas in the source structure around CACNG2.

Related topics
11
Source areas
4
Connected nodes
15
Extracted relationships
115
Related term clusters
7
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Interactions · 3 topics
Overview · 2 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CACNG2, MRD10, calcium voltage-gated channel auxiliary subunit gamma 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3JXT
Band
22q12.3 · 15 E1|15 36.92 cM
Bgee
right hemisphere of cerebellum · postcentral gyrus · Brodmann area 46 · superior frontal gyrus · prefrontal cortex
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How CACNG2 connects Entity context

The extracted context around CACNG2 shows recurring relationship patterns in the source. For example, CACNG2 → AMPA glutamate receptor complex, calcium channel activity, calcium ion transmembrane transport, calcium ion transport, cardiac conduction, cell junction, cell surface, cerebellar mossy fiber, channel regulator activity, cytosol, endocytic vesicle membrane, eye blink reflex, glutamatergic synapse, hippocampal mossy fiber to CA3 synapse, integral component of membrane, integral component of postsynaptic density membrane, ion transport, ionotropic glutamate receptor binding, membrane, membrane depolarization Another extracted example is CACNG2 → anterior cingulate cortex, anterior horn of spinal cord, Brodmann area 46, Brodmann area 9, cerebellar vermis, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, medulla oblongata, postcentral gyrus, prefrontal cortex, primary motor cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

CACNG2

Top relations

Gene ontology · 48
CACNG2 → AMPA glutamate receptor complex, calcium channel activity, calcium ion transmembrane transport, calcium ion transport, cardiac conduction, cell junction, cell surface, cerebellar mossy fiber, channel regulator activity, cytosol, endocytic vesicle membrane, eye blink reflex, glutamatergic synapse, hippocampal mossy fiber to CA3 synapse, integral component of membrane, integral component of postsynaptic density membrane, ion transport, ionotropic glutamate receptor binding, membrane, membrane depolarization
Bgee · 20
CACNG2 → anterior cingulate cortex, anterior horn of spinal cord, Brodmann area 46, Brodmann area 9, cerebellar vermis, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, medulla oblongata, postcentral gyrus, prefrontal cortex, primary motor cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus
RNA expression pattern · 20
CACNG2 → anterior cingulate cortex, anterior horn of spinal cord, Brodmann area 46, Brodmann area 9, cerebellar vermis, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, lobe of cerebellum, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, medial vestibular nucleus, medulla oblongata, postcentral gyrus, prefrontal cortex, primary motor cortex, right frontal lobe, right hemisphere of cerebellum, superior frontal gyrus
related to Interactions · 3
CACNG2 → DLG4, GRIA4, MAGI2
Band · 2
CACNG2 → 15 E1|15 36.92 cM, 22q12.3
Chr. · 2
CACNG2 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
CACNG2 → 36,703,752 bp, 78,004,228 bp
Aliases · 1
CACNG2 → CACNG2, MRD10, calcium voltage-gated channel auxiliary subunit gamma 2
Available structures · 1
CACNG2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3JXT
BioGPS · 1
CACNG2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene human calcium bp channel protein chr band chromosome 22 gamma subunit location also mouse stargazin membrane ampa ucsc function

CACNG2 relationships Subject–Predicate–Object triples

TTTA extracted 115 structured relationships around CACNG2. Examples in this analysis include CACNG2 → Aliases → CACNG2, MRD10, calcium voltage-gated channel auxiliary subunit gamma 2 and CACNG2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3JXT. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CACNG2AliasesCACNG2, MRD10, calcium voltage-gated channel auxiliary subunit gamma 21.00infobox
CACNG2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3JXT1.00infobox
CACNG2Band22q12.31.00infobox
CACNG2Band15 E1|15 36.92 cM1.00infobox
CACNG2Bgeeright hemisphere of cerebellum1.00infobox
CACNG2Bgeepostcentral gyrus1.00infobox
CACNG2BgeeBrodmann area 461.00infobox
CACNG2Bgeesuperior frontal gyrus1.00infobox
CACNG2Bgeeprefrontal cortex1.00infobox
CACNG2Bgeeright frontal lobe1.00infobox
CACNG2Bgeedorsolateral prefrontal cortex1.00infobox
CACNG2Bgeeentorhinal cortex1.00infobox
CACNG2BgeeBrodmann area 91.00infobox
CACNG2Bgeeanterior cingulate cortex1.00infobox
CACNG2Bgeeanterior horn of spinal cord1.00infobox
CACNG2Bgeelumbar subsegment of spinal cord1.00infobox
CACNG2Bgeecerebellar vermis1.00infobox
CACNG2Bgeelobe of cerebellum1.00infobox
CACNG2Bgeemedulla oblongata1.00infobox
CACNG2Bgeemedial dorsal nucleus1.00infobox
CACNG2Bgeeprimary motor cortex1.00infobox
CACNG2Bgeemedial vestibular nucleus1.00infobox
CACNG2Bgeefacial motor nucleus1.00infobox
CACNG2Bgeemedial geniculate nucleus1.00infobox
CACNG2BioGPSMore reference expression data1.00infobox
CACNG2Chr.Chromosome 22 (human)1.00infobox
CACNG2Chr.Chromosome 15 (mouse)1.00infobox
CACNG2DatabasesNCBI: entry; OMA: entry1.00infobox
CACNG2End36,703,752 bp1.00infobox
CACNG2End78,004,228 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around CACNG2 bring nearby vocabulary together. In this analysis, examples include Human, Gene and Calcium. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CACNG2
    • Human
    • Gene
    • Calcium
    • Channel
    • Ucsc
    • Location
    • Protein
    • Function
    • Search
    • Voltage-dependent
    • Voltage-gated
    • Chromosome
  • cacng2
    • Human
    • Gene
    • Calcium
    • Channel
    • Ucsc
    • Location
    • Protein
    • Function
    • Search
    • Voltage-dependent
    • Voltage-gated
    • Chromosome
  • protein
    • Encoded
    • Integral
    • Voltage-dependent
    • Membrane
    • Mouse
    • Stargazin
    • Gene
    • Subunit
    • Human
    • Cortex
    • E1
    • End
  • gene
    • Human
    • Location
    • Subunit
    • Ucsc
    • Chromosome
    • Bp
    • Chr
    • Protein
    • E1
    • End
    • Function
    • Search
  • l-type calcium channels
    • Channel
    • Protein
    • Gamma
    • Subunit
    • Cacng2
    • Gene
    • Function
    • Integral
    • Search
    • Voltage-dependent
    • Voltage-gated
    • Human
  • integral membrane protein
    • Membrane
    • Receptor
    • Encoded
    • Integral
    • Protein
    • Search
    • Voltage-dependent
    • Voltage-gated
    • Mouse
    • Stargazin
    • Gene
    • Subunit
  • function
    • Search
    • Voltage-gated
    • Chromosome
    • Location
    • Bp
    • Chr
    • Cortex
    • E1
    • End
    • Expressed
    • Integral
    • Receptor

Connections between topic areas Semantic bridges

For CACNG2, one of the stronger structural bridges in this analysis connects CACNG2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CACNG2 — Function · splits 10 ⟂ 6
CACNG2 — Interactions · splits 12 ⟂ 4
CACNG2 — Overview · splits 13 ⟂ 3

Map overview Semantic statistics

CACNG2

Nodes16
Edges15
Triples115
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around CACNG2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CACNG2 · EN edition · Analysis: TopicsToTalkAbout

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