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Thrombopoietin receptor

The thrombopoietin receptor also known as the myeloproliferative leukemia protein or CD110 (Cluster of Differentiation 110) is a protein that in humans is encoded by the MPL (myeloproliferative leukemia virus) oncogene.

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Discovery

4 related topics

Clinical relevance

4 related topics

Interactions

3 related topics

Function

1 related topics

Key facts & relationships

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Aliases
MPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR
Band
1p34.2 · 4 D2.1|4 54.61 cM
Bgee
testicle · mononuclear cell · monocyte · right frontal lobe · bone marrow cell
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Discovery

Function

Interactions

Clinical relevance

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Map overview Semantic statistics

Thrombopoietin receptor

Nodes20
Edges19
Triples86
Avg. degree1.9
Density0.1
Components1

How this topic connects Entity context

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Thrombopoietin receptor

Top relations

Gene ontology · 24
Thrombopoietin receptor → basophil homeostasis, cell population proliferation, cell surface, cell surface receptor signaling pathway, cellular response to hypoxia, cytokine receptor activity, cytokine-mediated signaling pathway, eosinophil homeostasis, Golgi apparatus, integral component of membrane, integral component of plasma membrane, membrane, monocyte homeostasis, neuron projection, neutrophil homeostasis, plasma membrane, platelet aggregation, positive regulation of lymphocyte proliferation, positive regulation of platelet formation, protein binding
Bgee · 19
Thrombopoietin receptor → blood, bone marrow cell, Brodmann area 9, bronchial epithelial cell, dorsal aorta, embryo, gastrula, left ovary, monocyte, mononuclear cell, morula, prefrontal cortex, right frontal lobe, spleen, sural nerve, testicle, tibiofemoral joint, vasculature of trunk, yolk sac
RNA expression pattern · 19
Thrombopoietin receptor → blood, bone marrow cell, Brodmann area 9, bronchial epithelial cell, dorsal aorta, embryo, gastrula, left ovary, monocyte, mononuclear cell, morula, prefrontal cortex, right frontal lobe, spleen, sural nerve, testicle, tibiofemoral joint, vasculature of trunk, yolk sac
related to Clinical relevance · 4
Thrombopoietin receptor → In, Inactivating, Specific, These
Band · 2
Thrombopoietin receptor → 1p34.2, 4 D2.1|4 54.61 cM
Chr. · 2
Thrombopoietin receptor → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Thrombopoietin receptor → 118,314,710 bp, 43,354,466 bp
Aliases · 1
Thrombopoietin receptor → MPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR
BioGPS · 1
Thrombopoietin receptor → More reference expression data
Databases · 1
Thrombopoietin receptor → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

thrombopoietin human bp protein gene chr band receptor mpl chromosome c-mpl cd110 leukemia formation location oncogene mutations myeloproliferative encoded virus

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Thrombopoietin receptorAliasesMPL, C-CD110, MPLV, THCYT2, TPOR, MPL proto-oncogene, thrombopoietin receptor, THPOR1.00infobox
Thrombopoietin receptorBand1p34.21.00infobox
Thrombopoietin receptorBand4 D2.1|4 54.61 cM1.00infobox
Thrombopoietin receptorBgeetesticle1.00infobox
Thrombopoietin receptorBgeemononuclear cell1.00infobox
Thrombopoietin receptorBgeemonocyte1.00infobox
Thrombopoietin receptorBgeeright frontal lobe1.00infobox
Thrombopoietin receptorBgeebone marrow cell1.00infobox
Thrombopoietin receptorBgeebronchial epithelial cell1.00infobox
Thrombopoietin receptorBgeesural nerve1.00infobox
Thrombopoietin receptorBgeeleft ovary1.00infobox
Thrombopoietin receptorBgeeBrodmann area 91.00infobox
Thrombopoietin receptorBgeeprefrontal cortex1.00infobox
Thrombopoietin receptorBgeeblood1.00infobox
Thrombopoietin receptorBgeegastrula1.00infobox
Thrombopoietin receptorBgeevasculature of trunk1.00infobox
Thrombopoietin receptorBgeetibiofemoral joint1.00infobox
Thrombopoietin receptorBgeeembryo1.00infobox
Thrombopoietin receptorBgeedorsal aorta1.00infobox
Thrombopoietin receptorBgeemorula1.00infobox
Thrombopoietin receptorBgeeyolk sac1.00infobox
Thrombopoietin receptorBgeespleen1.00infobox
Thrombopoietin receptorBioGPSMore reference expression data1.00infobox
Thrombopoietin receptorChr.Chromosome 1 (human)1.00infobox
Thrombopoietin receptorChr.Chromosome 4 (mouse)1.00infobox
Thrombopoietin receptorDatabasesNCBI: entry; OMA: entry1.00infobox
Thrombopoietin receptorEnd43,354,466 bp1.00infobox
Thrombopoietin receptorEnd118,314,710 bp1.00infobox
Thrombopoietin receptorEnsemblENSG000001174001.00infobox
Thrombopoietin receptorEntrez43521.00infobox

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