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Buformin

Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin. Buformin was marketed by German pharmaceutical company Grünenthal as Silubin.

Companies, Chemistry and animal toxicology & Anticancer properties

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Chemistry and animal toxicology

5 related topics

Anticancer properties

3 related topics

Antiviral properties

3 related topics

Toxicity

2 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
A10BA03 (WHO)
CAS Number
692-13-7 N
ChEBI
CHEBI:3209
ChEMBL
ChEMBL39736 Y
ChemSpider
2374 Y

Topics to explore

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Overview

Chemistry and animal toxicology

Toxicity

Mechanism of action

Anticancer properties

Antiviral properties

Synthesis

Advanced semantic analysis

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Map overview Semantic statistics

Buformin

Nodes30
Edges29
Triples61
Avg. degree1.93
Density0.066667
Components1

How this topic connects Entity context

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Buformin

Top relations

related to Toxicity · 13
Buformin → Another, DIBETOS, Hungary, In, Japan, Ltd, Nichi-Iko Pharmaceutical Co, Romania, Silubin Retard, Taiwan, The, US, Zentiva
related to Chemistry and animal toxicology · 8
Buformin → EST, Henry's, Hg, Its, Its Atmospheric, OH, The, Vapor
related to Pharmacokinetics · 7
Buformin → About, After, Binding, C-buformin, In, Serum, The
related to Anticancer properties · 4
Buformin → AMPK, Metformin, The, Warburg
related to Antiviral properties · 3
Buformin → Biguanides, Further, Middle East
related to Dosage · 3
Buformin → Romania, Silubin Retard, The
is a · 2
Buformin → metabolic antiviral that inhibits the mTOR pathway used by influenza and Middle East respiratory syndrome-related coronavirus, strong base
has effect · 2
Buformin → Its, The
related to Mechanism of action · 2
Buformin → Biguanides, They
3D model (JSmol) · 1
Buformin → Interactive image

Important terminology Word statistics

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Important terminology

mg oral metformin lactic acidosis cancer phenformin antiviral 25 biguanides silubin influenza effects administration renal normal constant rate kg glucose

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Buformin3D model (JSmol)Interactive image1.00infobox
BuforminATC codeA10BA03 (WHO)1.00infobox
BuforminCAS Number692-13-7 N1.00infobox
BuforminChEBICHEBI:32091.00infobox
BuforminChEMBLChEMBL39736 Y1.00infobox
BuforminChemSpider2374 Y1.00infobox
BuforminCompTox Dashboard (EPA)DTXSID60464201.00infobox
BuforminDrugBankDB04830 Y1.00infobox
BuforminECHA InfoCard100.010.6621.00infobox
BuforminExcretionRenal1.00infobox
BuforminFormulaC6H15N51.00infobox
BuforminKEGGD00595 Y1.00infobox
BuforminMolar mass157.221 g·mol−11.00infobox
BuforminPDB ligandBFR (PDBe, RCSB PDB)1.00infobox
BuforminPubChem CID24681.00infobox
BuforminRoutes of administrationOral1.00infobox
BuforminUNIIW2115E9C7B1.00infobox
Buforminis astrong base0.90text
Buforminis ametabolic antiviral that inhibits the mTOR pathway used by influenza and Middle East respiratory syndrome-related coronavirus0.90text

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    Min side: 3
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