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Buformin: Companies, Chemistry and animal toxicology & Anticancer properties

Buformin (1-butylbiguanide) is an oral antidiabetic drug of the biguanide class, chemically related to metformin and phenformin. Buformin was marketed by German pharmaceutical company Grünenthal as Silubin.

Language: English [EN]
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Buformin topic overview

The analysis highlights Companies, Chemistry and animal toxicology and Anticancer properties as prominent areas in the source structure around Buformin.

Related topics
22
Source areas
7
Connected nodes
29
Extracted relationships
61
Concept neighborhoods
15
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Chemistry and animal toxicology · 5 topics
Overview · 5 topics
Anticancer properties · 3 topics
Antiviral properties · 3 topics
Mechanism of action · 2 topics
Synthesis · 2 topics
Toxicity · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
A10BA03 (WHO)
CAS Number
692-13-7 N
ChEBI
CHEBI:3209
ChEMBL
ChEMBL39736 Y
ChemSpider
2374 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Chemistry and animal toxicology

Toxicity

Mechanism of action

Anticancer properties

Antiviral properties

Synthesis

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Buformin connects Entity context

The extracted context around Buformin shows recurring relationship patterns in the source. For example, Buformin → Another, DIBETOS, Hungary, In, Japan, Ltd, Nichi-Iko Pharmaceutical Co, Romania, Silubin Retard, Taiwan, The, US, Zentiva Another extracted example is Buformin → EST, Henry's, Hg, Its, Its Atmospheric, OH, The, Vapor. Use these groups to spot repeated connection types before inspecting the individual relationships.

Buformin

Top relations

related to Toxicity · 13
Buformin → Another, DIBETOS, Hungary, In, Japan, Ltd, Nichi-Iko Pharmaceutical Co, Romania, Silubin Retard, Taiwan, The, US, Zentiva
related to Chemistry and animal toxicology · 8
Buformin → EST, Henry's, Hg, Its, Its Atmospheric, OH, The, Vapor
related to Pharmacokinetics · 7
Buformin → About, After, Binding, C-buformin, In, Serum, The
related to Anticancer properties · 4
Buformin → AMPK, Metformin, The, Warburg
related to Antiviral properties · 3
Buformin → Biguanides, Further, Middle East
related to Dosage · 3
Buformin → Romania, Silubin Retard, The
is a · 2
Buformin → metabolic antiviral that inhibits the mTOR pathway used by influenza and Middle East respiratory syndrome-related coronavirus, strong base
has effect · 2
Buformin → Its, The
related to Mechanism of action · 2
Buformin → Biguanides, They
3D model (JSmol) · 1
Buformin → Interactive image

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

mg oral metformin lactic acidosis cancer phenformin antiviral 25 biguanides silubin influenza effects administration renal normal constant rate kg glucose

Buformin relationships Subject–Predicate–Object triples

TTTA extracted 61 structured relationships around Buformin. Examples in this analysis include Buformin → 3D model (JSmol) → Interactive image and Buformin → ATC code → A10BA03 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Buformin3D model (JSmol)Interactive image1.00infobox
BuforminATC codeA10BA03 (WHO)1.00infobox
BuforminCAS Number692-13-7 N1.00infobox
BuforminChEBICHEBI:32091.00infobox
BuforminChEMBLChEMBL39736 Y1.00infobox
BuforminChemSpider2374 Y1.00infobox
BuforminCompTox Dashboard (EPA)DTXSID60464201.00infobox
BuforminDrugBankDB04830 Y1.00infobox
BuforminECHA InfoCard100.010.6621.00infobox
BuforminExcretionRenal1.00infobox
BuforminFormulaC6H15N51.00infobox
BuforminKEGGD00595 Y1.00infobox
BuforminMolar mass157.221 g·mol−11.00infobox
BuforminPDB ligandBFR (PDBe, RCSB PDB)1.00infobox
BuforminPubChem CID24681.00infobox
BuforminRoutes of administrationOral1.00infobox
BuforminUNIIW2115E9C7B1.00infobox
Buforminis astrong base0.90text
Buforminis ametabolic antiviral that inhibits the mTOR pathway used by influenza and Middle East respiratory syndrome-related coronavirus0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Buformin bring nearby vocabulary together. In this analysis, examples include Oral, Acidosis and Lactic. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Buformin
    • Oral
    • Acidosis
    • Lactic
    • Mg
    • Inhibits
    • Patients
    • Phenformin
    • Renal
    • Silubin
    • Sold
    • Antiviral
    • Metformin
  • buformin
    • Oral
    • Acidosis
    • Lactic
    • Mg
    • Inhibits
    • Patients
    • Phenformin
    • Renal
    • Silubin
    • Sold
    • Antiviral
    • Metformin
  • synthesis
    • Action
    • Anticancer
    • Side
    • Administration
    • Cells
    • Effects
    • Glucose
    • Inhibits
    • Normal
    • Renal
    • Antiviral
    • Oral
  • mechanism of action
    • Anticancer
    • Side
    • Synthesis
    • Administration
    • Effects
    • Glucose
    • Normal
    • Renal
    • Antiviral
    • Biguanides
    • Oral
    • Buformin
  • anticancer properties
    • Normal
    • Side
    • Synthesis
    • Administration
    • Cells
    • Effect
    • Effects
    • Renal
    • Antiviral
    • Cancer
    • Oral
    • Buformin
  • lactic acidosis
    • Lactic
    • Patients
    • Renal
    • Buformin
    • Mg
    • Dose
    • Ml
    • Normal
    • Sold
    • Μg
    • Oral
  • antiviral properties
    • Influenza
    • Mtor
    • Side
    • Synthesis
    • Administration
    • Effects
    • Inhibits
    • Normal
    • Renal
    • Buformin
    • Oral
  • phenformin
    • Metformin
    • Chemically
    • Cancer
    • Antidiabetic
    • Effect
    • Inhibits
    • Buformin
    • Oral

Connections between topic areas Semantic bridges

For Buformin, one of the stronger structural bridges in this analysis connects Buformin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BuforminOverview · splits 24 ⟂ 6
BuforminChemistry and animal toxicology · splits 24 ⟂ 6
BuforminAnticancer properties · splits 26 ⟂ 4
BuforminAntiviral properties · splits 26 ⟂ 4
BuforminToxicity · splits 27 ⟂ 3
BuforminMechanism of action · splits 27 ⟂ 3
BuforminSynthesis · splits 27 ⟂ 3

Map overview Semantic statistics

Buformin

Nodes30
Edges29
Triples61
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around Buformin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Companies, Chemistry and animal toxicology & Anticancer properties, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Buformin · EN edition · Analysis: TopicsToTalkAbout

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